Navigation Links
Free shopping in a virtual bazaar of gene regulation data
Date:10/3/2007

An international team has opened a virtual bazaar, called PAZAR, which allows biologists to share information about gene regulation through individually managed 'boutiques' (data collections). According to research published in the online open access journal, Genome Biology, customers can access data without any charge from any boutique or extract information from the 'superstores' that aggregate data of similar types.

In deciphering the human genome sequence, researchers hope to understand the when and where of gene expression because this could speed development of novel cancer therapies or stem cell treatments for degenerative disease, and explain complex diseases such as diabetes.

Much of the information gathered in costly studies of gene regulation is poorly accessible if available at all. Individual research teams often generate databases or post files on the internet, but these data are fragmented and can be lost over time. The research team, led by Wyeth Wasserman at the University of British Columbia and Child & Family Research Institute, Vancouver, Canada, and colleagues from Bulgaria, Canada, France, and the USA, describe a novel approach to managing this information by bringing it together for the first time using PAZAR.

PAZAR is, explain the researchers, "an open-access and open-source database of transcription factor and regulatory sequence annotation". As such, it fulfils a longstanding need for a large data collection of regulatory sequences unrestricted by commercial concerns. Its novel shopping-mall-like structure (pazar is Bulgarian for shopping mall) will allow researchers to share data collections and computational predictions in an organized and accessible manner.

In order to demonstrate the advantages and features of PAZAR and its depth of annotation, the researchers used the Pleiades Promoter Project collection of brain-linked regulatory sequences as a show case. They have been working internationally with boutique operators and are currently expanding the data represented, and improving the curation tools. By bringing small data collections together Wasserman and colleagues are aiming to bring the data to international scientific customers and are encouraging other researchers to open new boutiques in this genomic mall.


'/>"/>

Contact: Charlotte Webber
press@biomedcentral.com
44-020-763-19980
BioMed Central
Source:Eurekalert

Related biology technology :

1. Jellyfish launches comparative shopping website
2. Checking out or getting out? Reasons for shopping cart abandonment
3. Virtual communities make online connections
4. Virtual-reality welding simulator an opportunity for Chippewa Valley college
5. Wisconsin Virtual Academy holds info sessions for new year
6. ZoomAlbum operates virtually
7. Wisconsin Virtual School selects eClassroom to power its program
8. Lands End Debuts Updated Virtual Model
9. Waukesha to Offer Virtual High School
10. Sex Steroid Regulation of Vasopressin Levels Secreted by hNT Neurons*
11. Reagents for Up and Down-Regulation of miRNA Activity in Mammalian Cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... ... February 22, 2017 , ... ... Spyker, PhD, MD former Acting Deputy Director in the FDA CDRH Division of ... Staff has joined the company as an Expert Consultant. , In Dr. Spyker’s ...
(Date:2/21/2017)... , Feb. 21, 2017 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or ... operational results for the three months ended December 31, 2016. ... -based life sciences and diagnostics company that develops and commercializes ... ... to build on the commercial milestones achieved in fiscal 2016," ...
(Date:2/21/2017)... ... February 21, 2017 , ... The medical potential of stem cells is both ... of medicine, due to their differentiating characteristics. Stem cells are unique as the have ... be induced to become tissue or organic-specific cells with special functions. , Stem ...
(Date:2/21/2017)... 2017  Lexus, a returning partner of the Amgen Tour ... exclusive automobile partner of the men,s and women,s events for the ... 2017 Amgen Tour of California will mark ... the best professional cycling teams in the world racing from Northern ... Amgen Breakaway from Heart Disease TM Women,s Race ...
Breaking Biology Technology:
(Date:2/3/2017)... , Feb. 3, 2017 A new independent ... Strategy Partners, LLP (IdSP) . Designed to fill a ... complex identity market, founding partners Mark Crego ... combined years just in identity expertise that span federal ... non-profit leadership. The Crego-Kephart combined expertise has a common ...
(Date:1/31/2017)... 2017  Spero Therapeutics, LLC, a biopharmaceutical company ... of bacterial infections, today announced it has acquired ... Pro Bono Bio Ltd (PBB) to bolster its ... forms of Gram-negative bacteria.   The assets acquired have ... PBB group company. "The acquisition of ...
(Date:1/24/2017)... Jan. 24, 2017 Biopharm Reports has ... laboratory use of nuclear magnetic resonance spectroscopy (NMR). ... and profiled current practices, developments, trends and end-user ... as growth and opportunities. These areas include growth ... instruments, needs and innovation requirements, hyphenated NMR techniques, ...
Breaking Biology News(10 mins):