Navigation Links
Foundation of UMDNJ Receives Grand Challenges Tuberculosis Biomarkers Grant

NEW BRUNSWICK, N.J., March 14, 2012 /PRNewswire-USNewswire/ -- The Foundation of UMDNJ, an affiliate of New Jersey Health Foundation, has received a tuberculosis (TB) biomarkers grant through the Bill & Melinda Gates Foundation's Grand Challenges in Global Health program, an initiative which seeks to overcome persistent bottlenecks in creating new tools that can radically improve health in the developing world.

With the grant, Dr. David Alland, professor of medicine, chief of infectious diseases, and director of the Center for Emerging and Re-Emerging Pathogens at UMDNJ-New Jersey Medical School, will pursue an innovative research project to identify and validate TB biomarkers, titled "Permeable Magnetic Nanoparticles for point-of-care tuberculosis diagnosis".

The Grand Challenges TB biomarkers program provides funding for groundbreaking research into TB biomarkers for the development of a low-cost, simple to use tool that can quickly and accurately diagnose TB in developing countries.

"There is an urgent need to break through barriers in biomarker research in order to develop a highly-sensitive point-of-care diagnostic to improve identification of active TB cases," said Chris Wilson, director of Global Health Discovery at the Bill & Melinda Gates Foundation. "We hope these innovative ideas lead to effective and affordable TB diagnostics that can make an impact on one of the world's deadliest infectious diseases."

Dr. Alland's project is one of ten Grand Challenges TB biomarkers grants awarded by the Bill & Melinda Gates Foundation.

Diagnostic assays are important components of tuberculosis (TB) control programs. Numerous methods exist that can rapidly detect Mycobacterium tuberculosis (MTB) in patient sputum (and potentially in other clinical samples). However, a major limitation common to virtually every one of these methods lies in the difficulty of extracting MTB from the clinical sample. This project will develop a simple, rapid and sensitive method to magnetically extract MTB from any volume of sputum that can reasonably be produced by a patient. MTB extracted with this method will be suitable for detection by many downstream technologies that can be adapted to point of care detection. This project will overcome a major roadblock in TB diagnostics, enabling many innovative diagnostic platforms to be applied to detecting this disease.

About Grand Challenges in Global Health
The Bill & Melinda Gates Foundation recognizes that solving our greatest global health issues is a long-term effort. Through Grand Challenges in Global Health, the foundation is committed to seeking out and rewarding not only established researchers in science and technology, but also young investigators, entrepreneurs and innovators to help expand the pipeline of ideas to fight diseases that claim millions of lives each year. We anticipate that additional grants will be awarded through the Grand Challenges program in the future.

About New Jersey Health Foundation
New Jersey Health Foundation (, established in 2002 as a not-for-profit public charity, is the parent company to the Foundation of UMDNJ (, which solicits private sector support for the University of Medicine and Dentistry of New Jersey and to Foundation Venture Capital Group, LLC,  ( which makes private equity investments in start-up technology companies founded by researchers affiliated with the University of Medicine & Dentistry of New Jersey.

About UMDNJ and the Center for Emerging Pathogens
The University of Medicine and Dentistry of New Jersey (UMDNJ) is New Jersey's only health sciences university with more than 6,000 students on five campuses attending the state's three medical schools, its only dental school, a graduate school of biomedical sciences, a school of health related professions, a school of nursing and New Jersey's only school of public health. UMDNJ operates University Hospital, a Level I Trauma Center in Newark, and University Behavioral HealthCare, which provides a continuum of healthcare services with multiple locations throughout the state.

The Center for the Study of Emerging and Reemerging Pathogens is a collection of interdepartmental laboratories located in the Medical Science Building at the UMDNJ-New Jersey Medical School in Newark.   

These laboratories share a new facility containing many pieces of top of the line/state-of-the-art equipment, used in scientific research. The facility comprises modern rooms dedicated to different purposes such as cell culture equipped with carbon dioxide incubators and a Biological Safety Cabinet, dishwashing and autoclaving (two dishwashers, two drying ovens and two autoclaves for sterilization), darkroom, PCR room, common equipment room containing gel dryers, ultracentrifuges, a lyopholizer, a tabletop centrifuge, & a scintillation counter.

The BSL-3 facility is located in the Medical Sciences Building occupying 725 square feet and has four rooms (3 modules, accessed through the 'common room') used for biohazardous work, plus an anteroom. The common room is a support area, containing freezers, an ELISA reader, a flow cytometer, a fluorescent microscope and a computer along with other standard laboratory equipment including a pass-through autoclave and sink. This facility is open for use by all investigators studying respiratory pathogens and is the location for the Center for BioDefense's research aims.

SOURCE New Jersey Health Foundation
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. John Grisham Joins Focused Ultrasound Surgery Foundation Board, Citing Novel Technologys Potential to Help Millions of Patients
2. ABMAC Foundation Announces Publication of an Historic Volume Documenting the Creation of a National Health Care System in Taiwan
3. Assay Designs(TM), Inc. and the Spinal Muscular Atrophy Foundation Announce Collaboration To Accelerate the Discovery of New Therapeutics for Spinal Muscular Atrophy (SMA)
4. diaDexus, Inc. and Living Heart Foundation Offer the PLAC(R) Test to Detect Hidden Risk for Heart Attack and Stroke in Retired NFL Players
5. Ameristar National Charity Golf Classic Raises More Than $1.1 Million for Buoniconti Fund to Cure Paralysis and Christopher & Dana Reeve Foundation
6. Former Scientific Director at Genomics Institute of Novartis Research Foundation Named President of Cell Therapeutics Europe
7. GBS/CIDP Foundation to Hold 10th International Symposium
8. Mirixa Corporation and the APhA Foundation Form Partnership
9. BIO Ventures for Global Health Receives $7 Million Grant from Gates Foundation to Engage Biotechnology in the Fight Against Neglected Diseases of the Developing World
10. Michael J. Fox Foundation Awards $2 Million Grant From EMD Serono to Research Projects on Cognitive Deficits in Parkinsons Disease
11. Canary Foundations Dr. Sanjiv Sam Gambhir Elected to the National Academies Institute of Medicine
Post Your Comments:
(Date:11/24/2015)... - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ICO) ... quarter ended September 30, 2015. Amounts, unless specified ... under International Financial Reporting Standards ("IFRS"). ... Andrew Rae , President & CEO of iCo ... value enriching for this clinical program, but also ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... the year and one of the premier annual events for pharmaceutical manufacturing: 2015 ... 8–11 November 2015, where ISPE hosted the largest number of attendees in more ...
(Date:11/24/2015)... , Nov. 24, 2015  Clintrax Global, Inc., a worldwide provider ... , today announced that the company has set a new ... 391% quarter on quarter growth posted for Q3 of 2014 to ... and Mexico , with the establishment of an ... 2015. --> United Kingdom and ...
(Date:11/24/2015)... ... November 24, 2015 , ... This fall, global software solutions leader SAP ... states to develop and pitch their BIG ideas to improve health and wellness in ... for votes to win the title of SAP's Teen Innovator, an all-expenses paid trip ...
Breaking Biology Technology:
(Date:11/9/2015)... , Nov. 9, 2015  Synaptics Inc. (NASDAQ: ... today announced broader entry into the automotive market with ... match the pace of consumer electronics human interface innovation. ... are ideal for the automotive industry and will be ... Europe , Japan ...
(Date:10/29/2015)... 29, 2015 Daon, a global leader in ... released a new version of its IdentityX Platform ... North America have already installed IdentityX v4.0 ... a FIDO UAF certified server component as ... activate FIDO features. These customers include some of the ...
(Date:10/27/2015)... In the present market scenario, security is ... industry verticals such as banking, healthcare, defense, electronic gadgets, ... for secure & simplified access control and growing rate ... of bank accounts, misuse of users, , and so ... laptops, and smartphones are expected to provide potential opportunities ...
Breaking Biology News(10 mins):