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ForteBio Launches Two Revolutionary High-Throughput, Label-Free Instruments: The Octet(R) RED384 and the Octet QK384
Date:6/22/2009

out two hours. These analyses have traditionally been conducted using SPR systems, which provide lower throughput and are substantially more expensive than the new Octet 384 series instruments."

The new systems support two 384- or 96-well plate positions and enable a full complement of samples to be run in one plate, while the second plate holds buffers, diluents and controls. The system is also capable of regeneration and re-racking of biosensors. Online biosensor regeneration drives the cost per sample down while conserving valuable ligand. Re-racking of used biosensors allows for optional offline regeneration and flexible assay methods, freeing up valuable instrument time to run more assays. The Octet 384 series instruments enable competitively low running cost in the 10-20 cents range per data point for quantitation and kinetic characterization assays.

The new systems are supported by Version 6 Octet software for data acquisition and analysis, which includes significant enhancements such as a 2:1 heterogeneous ligand binding model, data tracking and processing capabilities that assist in high-throughput screening. The new systems also include hardware and software robotic integration capabilities that support automation and database connectivity and can be licensed with optional 21 CFR Part 11 compliance tools.

ForteBio's Octet biosensors are disposable and are configured in a standard microplate format. Its biosensors simplify quantitation and kinetic characterization by eliminating throughput limitations of traditional SPR-based systems. Octet biosensors are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.

ForteBio also announced that the first batch of systems have been purchased by leading pharmaceutical and biotechnology companies after successful evaluations at customer sites.

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