Navigation Links
Following a Good Start to the Year Shire Reaffirms Full Year 2008 Financial Guidance
Date:4/25/2008

nt therapy products, recognizing gains of $9.4 million and $5.0 million respectively, for a total cash consideration of $15.3 million.

Expansion in Massachusetts

- Shire Human Genetic Therapies ("HGT") announced on February 14, 2008, that the Company will invest approximately $400 million over four years through 2011 to expand its Lexington, Massachusetts campus, making Lexington the global centre for HGTs research, development, and production. This will result in the creation of an estimated 680 additional full-time jobs over the next eight years, doubling the existing full time workforce.

Recent developments

VYVANSE approved to treat ADHD in adults

- On April 23, 2008 Shire announced that the FDA had approved the adult indication for VYVANSE, making it the first and only once-daily prodrug stimulant approved to treat adults with ADHD.

Shire acquires clinical candidate, arylsulfatase-A, for Metachromatic Leukodystrophy

- On April 24, 2008 Shire announced that it acquired from Zymenex A/S ("Zymenex") the global rights to the clinical candidate arylsulfatase-A ("ASA"), currently known as METAZYM(TM), being investigated for the treatment of Metachromatic Leukodystrophy ("MLD"). MLD is caused by a deficiency in the enzyme ASA which causes an excess concentration of sufatide in cells and an ensuing breakdown of myelin. There are approximately 2,000 MLD patients in developed world markets.

- The newly acquired ASA product has completed a Phase 1b clinical trial in 12 MLD patients in Europe and an extension to this study is ongoing. The product has received US FDA approval for its IND application to initiate a Phase 2 clinical trial and has been granted Orphan Drug designation in the US and in the EU. Shire will make a payment of US$135 million to Zymenex (which will be substantially expensed to Research & Development ("R&D")) for the acquisition of global rights to the product upon completion of the transaction, whi
'/>"/>

SOURCE Shire plc
Copyright©2008 PR Newswire.
All rights reserved

1

GOOD

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related biology technology :

1. Arena Pharmaceuticals Continues Phase 3 BLOOM Obesity Trial Following Independent Echocardiogaphic Data Safety Monitoring Board Review
2. Arena Pharmaceuticals Continues Phase 3 BLOOM Obesity Trial Following Independent Echocardiographic Data Safety Monitoring Board Review
3. Rosetta Genomics Announces Initiation of In Vivo Studies Following Successful Completion of First Milestone in MicroRNA-based Therapeutic Program for Liver Cancer
4. Sigma-Aldrich Achieves Double Accreditation as a Certified Reference Material Producer Following ISO/IEC 17025 and ISO Guide 34
5. In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement:
6. Velcura Therapeutics, Inc. Can Begin Clinical Trials Following Successful Investigational New Drug Application to U.S. FDA
7. Cardiums Corgentin Preclinical Program Shows High Levels of Targeting to Acutely Ischemic Heart Muscle Following Intracoronary Infusion
8. Nereus Pharmaceuticals Initiates Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer Following Encouraging Phase 1 Data
9. ITSSD: Russia Can Secure Greatest Biotech Market Advances Following US, Not EU Innovation Model
10. Optherion, Inc. Completes $37 Million Start Up Financing
11. Actress Aida Turturro Tells Americans to Start Now to Talk With Their Healthcare Provider About Taking Control of Their Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/16/2009)... by scientists at the University of East Anglia (UEA) ... domestic or agricultural waste to generate clean electricity. , ... of the National Academy of Sciences (PNAS), the ... by which some bacteria survive by ,breathing rocks,. , ... development of new microbe-based technologies such as fuel cells, ...
(Date:12/16/2009)... Martek Biosciences Corporation (Nasdaq: MATK ) today announced ... year ended October 31, 2009. Revenues for the fourth ... in the fourth quarter of fiscal 2008. Net income ... the fourth quarter of fiscal 2009, a 5% increase ... in last year,s fourth quarter. The fourth quarter ...
(Date:12/16/2009)... Blood America, Inc. (OTC Bulletin Board: CBAI), the ... http://www.cordblood-america.com ) focused on bringing the life ... policy, to families nationwide and internationally, said today ... total of $1.4 million so far in the ... for the year now tops $10 million. ,, ...
(Date:12/16/2009)... Sequenom, Inc. (Nasdaq: SQNM ), ... and Mr. David Pendarvis to its board of ... ,, Kenneth F. Buechler, Ph.D., was president, chief ... 1988 to 1994, Dr. Buechler was Biosite,s director ... was a senior research scientist for the diagnostics ...
Breaking Biology Technology:'Rock-breathing' bacteria could generate electricity and clean up oil spills 2Martek Announces Fourth Quarter and FY 2009 Financial Results 2Martek Announces Fourth Quarter and FY 2009 Financial Results 3Martek Announces Fourth Quarter and FY 2009 Financial Results 4Martek Announces Fourth Quarter and FY 2009 Financial Results 5Martek Announces Fourth Quarter and FY 2009 Financial Results 6Martek Announces Fourth Quarter and FY 2009 Financial Results 7Martek Announces Fourth Quarter and FY 2009 Financial Results 8Martek Announces Fourth Quarter and FY 2009 Financial Results 9Martek Announces Fourth Quarter and FY 2009 Financial Results 10Martek Announces Fourth Quarter and FY 2009 Financial Results 11Martek Announces Fourth Quarter and FY 2009 Financial Results 12Martek Announces Fourth Quarter and FY 2009 Financial Results 13Martek Announces Fourth Quarter and FY 2009 Financial Results 14Cord Blood America Says 2009 Debt Reduction Tops $10 Million 2Cord Blood America Says 2009 Debt Reduction Tops $10 Million 3Sequenom Appoints Two New Board Members 2Sequenom Appoints Two New Board Members 3
... Pays Tribute to America,s Top Research Scientists -- Also Featured ... Board -MELBOURNE, Australia, May 18 Dr. Rudy Tanzi, Prana ... the Director of the Genetics and Aging Research Unit at ... featured in a six-page photo spread, in the June issue ...
... 2 Studies Evaluating KRX-0401 in Advanced Renal Cell Carcinoma, ... , NEW YORK, May 18 Keryx Biopharmaceuticals, ... four abstracts on KRX-0401 (Perifosine), the Company,s Akt-inhibitor for ... place at the 45th Annual Meeting of the American ...
... Institut Pasteur and Merieux Alliance,have signed a letter of ... The Institut Pasteur and Merieux Alliance (which ... would like to,pool their resources and efforts to fight ... , , - Clinical diagnostics and ...
Other Biology Technology:ROCK STARS OF SCIENCE: Prana's Co-Founding Scientist, Rudy Tanzi Teams up with Star-Powered Cast in GQ Photoshoot 2ROCK STARS OF SCIENCE: Prana's Co-Founding Scientist, Rudy Tanzi Teams up with Star-Powered Cast in GQ Photoshoot 3Keryx Biopharmaceuticals Announces Poster Presentations Highlighting Clinical Activity of KRX-0401 (Perifosine) at the Upcoming Annual Meeting of the American Society of Clinical Oncology 2Keryx Biopharmaceuticals Announces Poster Presentations Highlighting Clinical Activity of KRX-0401 (Perifosine) at the Upcoming Annual Meeting of the American Society of Clinical Oncology 3Keryx Biopharmaceuticals Announces Poster Presentations Highlighting Clinical Activity of KRX-0401 (Perifosine) at the Upcoming Annual Meeting of the American Society of Clinical Oncology 4The Institut Pasteur and Merieux Alliance Take First Step Towards a Long-Term Research Partnership in the Field of Infectious Diseases 2The Institut Pasteur and Merieux Alliance Take First Step Towards a Long-Term Research Partnership in the Field of Infectious Diseases 3
(Date:12/16/2009)... SHORES, Calif. and PALM HARBOR, Fla., Dec. ... (OTC Bulletin Board: CICI), a leading supplier ... automation in the financial industry* and the ... Docubase Systems Inc. ("Docubase"), a leading International ... today that they have entered an agreement ...
(Date:12/16/2009)... -- BIO-key International, Inc. (OTC Bulletin Board: ... solutions, today announced that SC Magazine, one ... named BIO-key International the 2009 Innovator of ... Biometrics. ,, (Logo: http://www.newscom.com/cgi-bin/prnh/20050509/BIOKEYLOGO ) ... SC Magazine, "Biometric providers have been trying ...
(Date:12/15/2009)... As soon as babies are born, they are susceptible ... For up to a month, their immune systems aren,t ... often minor, they can lead to serious problems if ... of Missouri researchers have pinpointed a group of depleted ... vaccine. , "We,re trying to improve the immune system ...
Breaking Biology News(10 mins):CIC Teams with Docubase Systems to Deliver eSignature Enabled Document Management Solutions 2CIC Teams with Docubase Systems to Deliver eSignature Enabled Document Management Solutions 3CIC Teams with Docubase Systems to Deliver eSignature Enabled Document Management Solutions 4BIO-key(R) Selected as 2009 Industry Innovator in Biometrics by SC Magazine 2BIO-key(R) Selected as 2009 Industry Innovator in Biometrics by SC Magazine 3Researchers work on vaccine to improve immune system in newborns 2Bipolar Disorder May Be Tied to Body Clock 62199 1Bipolar Disorder May Be Tied to Body Clock 62199 2New USB technology adds accountability and convenience to wellness programs 62196 1New USB technology adds accountability and convenience to wellness programs 62196 2Why Some Vaccines May Require A Booster 62192 1Why Some Vaccines May Require A Booster 62192 2Why Some Vaccines May Require A Booster 62192 3
... oxygen concentration in the earth's atmosphere shows that a sharp ... the evolutionary boost they needed to dominate the planet, according ... author of a paper published Sept. 30 in the ... the abundance of carbon 13, a byproduct of photosynthesis, ...
... male, the female North American barn swallow still comparison-shops for ... their looks -- the reddish color of the males' breast ... not as dark as other males in the population, the ... copulate with another male, according to a Cornell University study ...
... Sinai School of Medicine researchers first to discover that a ... discovery of the structure of DNA by James Watson and ... stated that the DNA itself codes for the appropriate pairings ... is on the original strand of DNA then its partner, ...
Other Biology News:Oxygen increase caused mammals to triumph, researchers say 2Looks matter to female barn swallows 2Looks matter to female barn swallows 3
Rabbit polyclonal to XTP4 ( Abpromise for all tested applications). entrezGeneID: 84299 SwissProtID: Q9BRT3...
Sold individually or included in the MasterAmp™ PCR Optimization Kit without ammonium sulfate. Includes dNTPs, buffer, and varying amounts of MgCl2 and the MasterAmp™ PCR Enhancer (with be...
Quinolinate phosphoribosyltransferase...
Mouse monoclonal [4C4] to Y14 ( Abpromise for all tested applications). entrezGeneID: 9939 SwissProtID: Q9Y5S9...
Biology Products: