Navigation Links
Flu jab for bacteria
Date:3/31/2010

Viruses can wreak havoc on bacteria as well as humans and, just like us, bacteria have their own defence system in place, explains Professor John van der Oost, at the Society for General Microbiology's spring meeting. Uncovering the workings of the bacterial "immune system" could be used to keep industrial microbes at peak performance.

Professor van der Oost and his team at Wageningen University in the Netherlands have spent the last three years working out the molecular details of the immune system called CRISPR that is present in bacteria. The recently discovered CRISPR defence system differs from the immune system in higher organisms in that acquired immunity can be passed down future generations. This means bacterial offspring are protected from viral attack even before they are exposed to the invading virus.

Specific bacterial proteins recognise infectious viruses, called bacteriophages, by detecting foreign DNA. These proteins take the viral DNA and insert it into the bacterial genome at very specific locations. "Storing the information in this way gives the bacteria a lasting 'memory' of the harmful virus that subsequently confers immunity much like our own immune systems," said Professor van der Oost. Upon future attack by the same virus, the DNA sequence of the invader is quickly recognised and destroyed by the bacteria.

Understanding the exact mechanisms of the CRISPR defence system could have big economic rewards for industry. "We can exploit this system and expose bacteria to artificial or modified bacteriophages whose DNA could be stored. This would be exactly like giving them a flu jab and protect them against a real attack in the future. For industrially-important bacteria this could be a great cost-saving method to reduce viral infections that may compromise yields of bacterial products. It's a classic example of vaccinating the workforce to increase its productivity."


'/>"/>

Contact: Laura Udakis
l.udakis@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert  

Page: 1

Related biology technology :

1. How immune cells sniff out bacteria
2. Advanced Life Sciences Receives FDA Guidance on Approval Pathway for Restanza in Community Acquired Bacterial Pneumonia and Biodefense Indications
3. Bacteria toxic to wound-treating maggots
4. Rock-breathing bacteria could generate electricity and clean up oil spills
5. Argonne Scientists Use Bacteria to Power Simple Machines
6. Broad-Spectrum Antibacterial Activity is the Most Important Driver of Antibiotic Selection for Nosocomial Pneumonia In Europe
7. EUCODIS Bioscience to Explore Novel Enzymatic Activities in Antarctic Bacteria Library From Bio Sidus
8. New biosensor can detect bacteria instantaneously
9. NovaBay(R) Presents Data Confirming Its Aganocide(R) Compounds Are Effective In Killing Bacteria That Have Developed Multidrug-Resistance
10. Making bacteria make useful proteins
11. Building better bone replacements with bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Flu jab for bacteria
(Date:9/30/2014)... 30, 2014 BioHealth Innovation, Inc. ... biohealth innovations and increasing access to early-stage funding in ... venture capitalist, Tania Fernandez , Ph.D., has joined ... will be a member of the management team for ... to $50 million in seed and early-stage equity investments ...
(Date:9/30/2014)... 2014 The custom stainless steel fabrication ... Show 2014. The Boston Area Chapter of ISPE (International ... day-long event for Wed., Oct. 1 at Gillette Stadium ... the largest in ISPE Boston’s long history, with more ... attendees expected. , HOLLOWAY AMERICA President David Simpson ...
(Date:9/30/2014)... 30, 2014 On September 11, Pharma IQ ... in anticipation of a session that he will lead on ... scheduled for February 17-18, 2015 in London. In the ... asked Dr. Sherley to respond to several questions on the ... to evaluating stem cell toxicity, and future trends in the ...
(Date:9/30/2014)... September 30, 2014 The ... IACRN), a non-profit organization based in Pittsburgh, Pennsylvania, ... and Safety (ACRES), a Massachusetts non-profit charitable ... alliance agreement, setting the stage for multiple collaborative ... clinical research quality and safety through specialized nursing ...
Breaking Biology Technology:Seasoned Life Sciences Venture Capitalist Tania Fernandez Joins BHI to Help Manage New BioHealth Gap Fund 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 3Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 2Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 3Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 4IACRN and ACRES to Support Clinical Research Nurses 2IACRN and ACRES to Support Clinical Research Nurses 3
... technologys sake. And yet a visiting space alien that is ... for believing thats what most of us are doing. We ... the technology and almost none of our energy into assessing ... From the way we allocate our energy and attention, it ...
... MADISON, Wis. — With the University of Wisconsin System ... of creating two separate statewide networks, Gov. Jim Doyle ... efforts. , ,"It's more sensible for taxpayers to have ... spokesperson Dan Leistikow. , ,Initial discussions last year about ...
... a new product, behave just like parents jumping in ... of the incubation wing is often replaced by a ... Dilbertish style revolution. Objects do fly, even though they ... Everyone shares the excitement and all fights are well ...
Cached Biology Technology:Why are you buying technology? 2Why are you buying technology? 3Governor tells UW to scrap network plans 2Naming that thing... again? 2Naming that thing... again? 3Naming that thing... again? 4
(Date:9/30/2014)... Institutes of Health (NIH) awarded Lawrence Livermore National ... electrode array system that will enable researchers to ... resolution and scale. , LLNL,s grant-funded project is ... BRAIN (Brain Research through Advancing Innovative Neurotechnologies) ... our understanding of the human mind and uncover ...
(Date:9/30/2014)... of environmental scientists and engineers, led by Clemson ... three-year, $5.25 million grant from the U.S. Department ... to make a direct positive impact on South ... disposal of radioactive contaminants. , "Understanding the scientific ... with environmental aspects of nuclear technologies is imperative ...
(Date:9/30/2014)... New England Journal of Medicine reports positive results ... crizotinib against the subset of lung cancer marked by ... of 50 patients with advanced non-small cell lung cancer ... was 72 percent, with 3 complete responses and 33 ... takes for the disease to resume its growth after ...
Breaking Biology News(10 mins):NIH taps lab to develop sophisticated electrode array system to monitor brain act 2NIH taps lab to develop sophisticated electrode array system to monitor brain act 3Researchers get $5.25 million to advance nuclear technologies in South Carolina 2NEJM: Crizotinib effective in Phase 1 trial against ROS1 lung cancer 2
... Calif. Researchers at Sandia National Laboratories will use ... high-throughput assays as part of a multiproject, $34 ... (ARPA-E) aimed at developing advanced biocatalyst technologies that ... transportation. The ARPA-E program is Reducing Emissions ...
... scientific team has discovered a gene associated with a ... variant may be an actual cause of this form ... children. "Because asthma is a complex disease, with ... recurrent asthma occurring between ages two and six," said ...
... OVERVIEW: Straight from Stockholm: Randy Schekman, Ph.D., ... New Orleans after receiving the 2013 Nobel Prize in ... 2,500 poster presentations about the latest research on cellular ... cell interactions and the proverbial much, much more. ...
Cached Biology News:Converting natural gas to liquid transportation fuels via biological organisms 2Converting natural gas to liquid transportation fuels via biological organisms 3Novel gene variant found in severe childhood asthma 2
... Price (1996) • This issue ... chemistry and the purification and ... on the following procedures is ... amino acid analysis and the ...
Edited by D.M. Gersten (1996) Provides comprehensive descriptions of the techniques available for analytical gel electrophoresis of proteins and offers clear step-by-step protocols for all of the m...
...
All serum is collected from U.S.D.A. fryers and broilers. Pricing: $15/unit for 1 - 10 units; $12/unit for 11 - 50 units...
Biology Products: