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Flagship Biosciences Expands Digital Pathology with Pharmaceutical Biostatistics Services
Date:8/1/2013

e quantitation will be expected. “Where previously we relied on a pathologist to give a manual subjective score, there were limits to what a statistician could do with the data, said Dr. Steven Potts, CEO of Flagship Biosciences. “With the newer techniques that Flagship Biosciences is developing, there is a greater need for biostatistics, and also an emerging discipline of pathology statistics. This growth is a natural expansion as the discipline of tissue-based pathology develops towards a more quantitative discipline. Our expansion of in-house biostatistics capabilities will also strengthen our ongoing tissue-based companion diagnostics programs.”

With new approaches to multiple measures of tissue markers which are rich in quantitative data, multivariate statistics becomes central. Even with single-value measurements in immunohistochemistry or immunofluorescence, the correct approach to determining a therapeutic cut-point requires statistics expertise. A statistician must fully understand the process of a pathology study in order to provide advice on critical decisions like sample size, adequate power, outlier analysis, and bias.

Flagship Biosciences is a fast-growing histopathology services firm that works with over one hundred drug and medical device clients and fourteen of the largest fifteen global pharmaceutical companies. Flagship supports discovery and CLIA/GCP clinical trials in quantitative pathology. Flagship’s biostatistics services improve upon their industry-leading digital pathology knowledge and expertise.

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