Navigation Links
First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU
Date:3/18/2011

e to a PKU treatment plan."  

To measure neuropsychiatric impairment, patients already treated at PKU clinics were screened for psychiatric distress and cognitive impairment using standard neuropsychiatric assessment tools.  Individual test results were then correlated to patients' blood Phe levels.  The study found that patients who screened positive for psychiatric deficiencies had significantly higher blood Phe levels than patients who screened negative.

"Up until now, lowering blood Phe levels has been the only success measure in the treatment of PKU.  We believe ADAPT study results are an important step toward improving the overall care of PKU patients.  The data indicate that physicians have the opportunity to more easily identify those patients with neuropsychiatric and cognitive impairments, and better understand the impact of the link between Phe and these deficits, by simply incorporating mental health screening into the current standard of care," said Hank Fuchs, M.D., Chief Medical Officer of BioMarin.

Additional KUVAN Poster Presentations at ACMGOther presentations at ACMG describe ongoing studies designed to further examine the use of KUVAN® (sapropterin dihydrochloride) Tablets for PKU, with endpoints of neuropsychiatric effects and long-term safety in children. KUVAN is the first and only FDA approved treatment to reduce blood Phe levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin (BH4-) responsive PKU, and is to be used in conjunction with a Phe-restricted diet.

  • PKU-016 / ASCEND Outcomes Study: Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in PKU Subjects – Clinical Study Design (S Stahl, et al, University of California, San Diego, Calf.)  [Poster 189 – March 18, 10:30-11:30 am]. The ongoing double-blind, placebo-controlled, randomized (1:1) 26-week outcomes study is evaluating the safety and efficacy of S
    '/>"/>

  • SOURCE BioMarin Pharmaceutical Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7 8

    Related biology technology :

    1. FDA Approves First-of-Its-Kind HIV Test Which Can Detect HIV Days Earlier Than Current U.S. Tests
    2. InNexus Biotechnology Announces Launch of Large Scale Primate Study of DXL625
    3. RAND study finds increase in piracy and terrorism at sea
    4. Merrimack Pharmaceuticals Initiates Enrollment in a Phase 1 Study of MM-121, an ErbB3 Antagonist
    5. Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure
    6. Logical Therapeutics Inc. Announces Results of Phase 1b Clinical Study of its Naproxen Prodrug
    7. Video: CSL Behring Provides $1.2M Grant for Worlds First Study of Postpartum Women with VWD, Common Bleeding Disorder
    8. RainDance and Scripps to Collaborate on Targeted Sequencing for Wellderly Study
    9. Preliminary Report of American Biotech Labs HIV Study Featured in Inaugural Issue of Journal of the Science of Healing Outcomes
    10. Pharmasset Reports Preliminary Results of a 4-week Proof-of-Concept Combination Study of R7128 for the Treatment of Chronic Hepatitis C in Genotype 2 or 3 Non-Responders
    11. ESBATech Announces Successful Completion of Phase I Clinical Study for Lead Antibody Fragment in Ophthalmic Indications
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:1/22/2015)... The laboratory information management systems market ... number of technological advancements due to factors such as ... to integrate healthcare systems, and increasing government support for ... integration. Key players in the market focus on technological ...
    (Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently was ... Pre-Conference seminar on probiotics in San Diego, CA. , ... conference for health care professionals. This year’s pre-conference seminar was ... in health. Dr. Leyer spoke about the emerging topics and ...
    (Date:1/22/2015)... DIEGO , Jan. 22, 2015   Cypher ... and Sequenom, Inc. (NASDAQ: SQNM ), ... development agreement for next generation noninvasive prenatal tests ... genome interpretation technology, called Mantis™, to advance analysis ...
    (Date:12/24/2014)... 24, 2014  United Therapeutics Corporation (NASDAQ: UTHR ... MDT ) has submitted a pre-market approval application to ... use of Medtronic,s SynchroMed ® II implantable drug ... with United Therapeutics, Remodulin ® (treprostinil) Injection delivered ...
    Breaking Biology Technology:Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4
    ... SCOTTSDALE, Ariz., March 17, 2011 Delta Point, Inc., ... and developing business relationships, has named Ed Weimer as ... numerous awards for his ability to highly motivate, develop ... providing the strategic vision to contribute to the organization,s ...
    ... 2011 Genesis Biopharma, Inc. (OTC Bulletin ... targeted cancer therapies, today announced it has appointed William ... Andrews has three decades experience in biotechnology research and ... of Sierra Sciences, LLC, a company he founded in ...
    ... 2011 A first-of-its-kind study of gene therapy in ... all patients who received the treatment had "clinically meaningful ... "The study demonstrates that the promise of ... says study lead author and co-principal investigator Peter LeWitt, ...
    Cached Biology Technology:Ed Weimer Joins Delta Point, Inc. as Executive Account Director 2Genesis Biopharma Appoints William H. Andrews Ph.D. to Board of Directors 2Study: 'Meaningful improvements' Using Gene Therapy in Parkinson's Disease 2Study: 'Meaningful improvements' Using Gene Therapy in Parkinson's Disease 3
    (Date:12/22/2014)... (NASDAQ: NXTD and NXTDW) ("NXT-ID" or the ... commerce market, announces it has retained famous pickpocket, entertainer and ... CES debut of the Wocket™ biometric smart wallet.  ... booth January 6th and 7 th , 2015, demonstrating some ...
    (Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & ... http://photos.prnewswire.com/prnh/20130307/600769 ... introduced the fingerprint reading feature with the iPhone 5S. ...
    (Date:12/19/2014)... , Dec. 18, 2014   LaunchKey , the ... the post-password and Internet of Things era, today announced ... The venture round was led by Metamorphic Ventures with ... Venture Partners, VegasTechFund, and others.  LaunchKey has raised $4 ...
    Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3
    ... transmitted diseases (STDs) requires treatment of the sexual partners ... infected men with antibiotics to give their partners is ... the partners, according to an article in the Sept. ... Men with chlamydia or gonorrhea were more likely to ...
    ... into a tumor, seal the exits and detonate a ... cells unscathed. , MIT researchers have designed a nanoparticle ... "nanocell" proved effective and safe, with prolonged survival, against ... mice. , The work will be reported in the ...
    ... A new study released in Science (via Science Express ... in the diversity of fish in the open ocean ... Teasing apart the effects of climate change and fishing ... clear link to overfishing and highlight a surprising global ...
    Cached Biology News:New study: Sexually transmitted disease treatment can be effectively administered by sex partners 2New study: Sexually transmitted disease treatment can be effectively administered by sex partners 3MIT engineers an anti-cancer smart bomb 2Scientists discover global pattern of big fish diversity in open oceans 2Scientists discover global pattern of big fish diversity in open oceans 3Scientists discover global pattern of big fish diversity in open oceans 4Scientists discover global pattern of big fish diversity in open oceans 5
    Detect and measure levels of mouse IgG3 antibody isotypes quickly and easily....
    ... Each vial contains 200 g of ... receptor sequence (C-terminal amino acids 380-402; GLTPSAWEASSLRSSRHSGLSHF. ... an antigen for production of Cayman's EP1 ... can be used in conjunction with this ...
    ... IgG FITC is used as the ... on tissues or culture cells where ... rabbits. It is highly recommended that ... the primary antibody, be included in ...
    TRBP1 Antibody...
    Biology Products: