Navigation Links
First high-resolution images of bone, tooth and shell formation
Date:3/12/2009

Researchers at Eindhoven University of Technology (TU/e) have for the first time made high-resolution images of the earliest stages of bone formation. They used the world's most advanced electron microscope to make three-dimensional images of the nano-particles that are at the heart of the process. The results provide improved understanding of bone, tooth and shell formation. For industrial applications, they promise better materials and processes based on nature itself. The findings form the cover story of Science magazine's Friday 13 March edition.

Led by dr. Nico Sommerdijk, the researchers imaged small clusters with a cross-section of 0.7 nanometer in a solution of calcium carbonate (the basic material of which shells are made). They showed for the first time that these clusters, each consisting of only about ten ions, are the beginning of the growth process through which the crystalline biomineral is ultimately formed.

To do this they used the very high resolution of a special electron microscope: the cryoTitan (of FEI Company). This enabled them, as the first in their field of research, to make three-dimensional images of very rapidly frozen samples. These showed how the clusters in the solution nucleate into larger, unstructured nano-particles with an average diameter of around thirty nanometers.

An organic surface applied by the researchers ensures that these nano-particles can grow into larger particles, in which crystalline regions can later form by ordering of the ions. The TU/e researchers also demonstrated a second function of the organic layer: it controls with great precision the direction in which the mineral can grow into a fully fledged biomineral. They now hope to show that the mechanism they have identified also applies to the formation of other crystalline biominerals, and perhaps even to other, inorganic materials.

This is important for research into bone growth and bone-replacement materials.
'/>"/>

Contact: Nico Sommerdijk
N.Sommerdijk@tue.nl
31-651-627-482
Eindhoven University of Technology
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Reclast(R) Receives US FDA Approval as First and Only Once-Yearly Treatment for Women With Postmenopausal Osteoporosis
2. GlaxoSmithKline Recognizes University of Michigans Dr. Daniel F. Hayes as the First Recipient of the Gianni Bonadonna Breast Cancer Award
3. Kewaunee Scientific Announces First Quarter Results and Quarterly Dividend
4. Genmab Announces 2007 First Half Year Results
5. Pharsight Achieves First License Sale for Public-Source Database
6. Novare Announces First Ever Single Port Laparoscopic Kidney Removal (Nephrectomy) Using RealHand(TM) HD Instruments
7. ExonHit Therapeutics: Allergan and ExonHits First Collaboration Compound to Begin Human Clinical Trials
8. China Medical Technologies Reports First Quarter Financial Results
9. Pressure BioSciences, Inc. Issued First Patent in Canada
10. Peregrine Pharmaceuticals to Announce First Quarter FY 2008 Financial Results
11. Exelixis Reports Encouraging Interim Data From a Phase 2 Trial of XL647 as First-Line Therapy for Non-Small Cell Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
First high-resolution images of bone, tooth and shell formation
(Date:9/19/2014)... (Nasdaq: ITMN ) today announced that it ... litigation in the Delaware Court of Chancery relating to ... August 22, 2014, among Roche Holdings, Inc., Klee Acquisition ... Memorandum of Understanding, the Company agreed to make certain ... the amendment to the Company,s Schedule 14D-9 to be ...
(Date:9/19/2014)... that use light, rather than electricity, to move ... energy efficiency is a growing concern as chips, ... components of optical circuits light emitters, modulators, ... build. One promising light source for optical chips ... properties when deposited as a single, atom-thick layer. ...
(Date:9/19/2014)... , September 19, 2014 Biotech ... development of emerging drug systems and advanced Laboratory Instrumentation. ... and Company (NYSE: BDX ), Thermo Fisher ... Inc. (NASDAQ: RGDO ), Sangamo Biosciences Inc. ... HOLX) Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI" ...
(Date:9/19/2014)... , September 19, 2014 BioTech ... developments, patents and results of studies and trials.  Companies ... and Company (NYSE: LLY ), Gilead Sciences ... CELG ) and Arena Pharmaceuticals Inc. (NASDAQ: ... in developing prodrug therapeutics for the treatment of cancer, ...
Breaking Biology Technology:InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 2InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 3InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 4InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 5InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 6InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 7InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 8InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 9InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 10InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 11InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 12InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 13InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 14InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 15InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 16InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 17InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 18InterMune Reports Memorandum of Understanding in Connection with Consolidated Delaware Action 19Toward optical chips 2Toward optical chips 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 2Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 4Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 5Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 6Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 7Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7
... and pharmaceutical firms are developing a host of ... discovery process, reports Genetic Engineering and Biotechnology ... rely on a combination of high-throughput screening methods, ... an article in the July issue ( http://www.genengnews.com/articles/chitem.aspx?aid=2527 ...
... Lilly,s Structure-Based Drug Discovery Capabilities, INDIANAPOLIS, and SAN ... LLY ) and SGX Pharmaceuticals, Inc. (Nasdaq: SGXP ... merger agreement,providing for the acquisition of SGX in an ... biotechnology company focused on drug,discovery and development in the ...
... , ... St. Louis, MO (PRWEB) July 8, 2008 -– In a new ... describes the process of food biotechnology, as well as the safety and ... on a daily basis make numerous decisions about the food they eat. ...
Cached Biology Technology:Lilly to Acquire SGX Pharmaceuticals 2Lilly to Acquire SGX Pharmaceuticals 3Lilly to Acquire SGX Pharmaceuticals 4Lilly to Acquire SGX Pharmaceuticals 5Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 2Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 3Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 4
(Date:9/18/2014)... A sleep-promoting circuit located deep in the primitive brainstem ... by researchers at Harvard School of Medicine and the ... this is only the second "sleep node" identified in ... necessary and sufficient to produce deep sleep. , Published ... study demonstrates that fully half of all of the ...
(Date:9/18/2014)... Worcester, Mass. A novel robotic system that can ... currently being tested as part of a biomedical research ... with the aim of determining if the robot, in ... biopsies faster, more accurate, less costly, and less discomforting ... potential to deliver prostate cancer therapies with greater precision. ...
(Date:9/18/2014)... many times it,s demonstrated, it,s still hard to ... But by using a signaling system called "quorum ... to suit their population. In short, some bacteria ... act accordingly. , Once the population of quorum-sensing ... innocuous to pathogenic, or from unhelpful to helpful. ...
Breaking Biology News(10 mins):No sedative necessary: Scientists discover new 'sleep node' in the brain 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3
... at the University of Liverpool have discovered that the ... million years old and took its present shape about ... in collaboration with the University of Amsterdam and Petrobras, ... taken from two boreholes near the mouth of the ...
... well-fed, clonal organisms in the Caribbean Sea as the ... Pacific, report researchers from the Smithsonian Tropical Research Institute ... shows that if a species could shift from clonal ... for extinction, millions of years later. Closure of the ...
... A study conducted by researchers at Ben-Gurion University of the ... indicates that approximately 16 percent of public health care workers ... regardless of the severity. The study,just published in the ... 1,835 public health workers in Minnesota, Ohio and West Virginia ...
Cached Biology News:Sex in the Caribbean: Environmental change drives evolutionary change -- eventually 21 in 6 health workers won't report in flu pandemic -- study by Ben-Gurion U. researchers 21 in 6 health workers won't report in flu pandemic -- study by Ben-Gurion U. researchers 3
... G bind specifically to Fc regions of ... G conjugates are commonly used as affinity ... subtypes from serum, hybridoma ascites fluids, tissue ... reagents are also commonly used to capture ...
... (10 min) assay can detect H2O2 or ... (ADHP). H2O2 oxidizes ADHP in a 1:1 ... (excitation at 530-571 nm, emission at 590-600 ... in a one-step, homogeneous, no wash assay ...
... The Reverse-iT™ One-Step Kit is ... reproducibility in RT-PCR. It has been ... process. The Reverse-iT™ One-Step Kit ... RTases and ABgene®s Thermoprime Plus DNA ...
... for protein pull-down experiments to ... proteins. An order of Sphingobeads ... beads with 10 nmol of ... of the alkyl chain; enough ...
Biology Products: