Navigation Links
Financial Results for Full Year 2008: NicOx in a Unique Position to Deliver Significant Shareholder Value
Date:2/26/2009

cinod's efficacy and achieves target product profile

In 2008, NicOx successfully completed the phase 3 clinical program for naproxcinod in patients with OA of the knee (the 301 and 302 studies) and hip (the 303 study), with all three studies achieving highly statistically significant results on all three co-primary efficacy endpoints (the WOMAC(TM) pain subscale, WOMAC(TM) function subscale and subject's overall rating of disease status), as well as good overall safety and tolerability.

    - In July, the top-line results of the 52-week safety extension of the
      301 study were reported, which revealed no unexpected safety findings
      and showed a good overall long term safety for both doses of
      naproxcinod.

    - The 302 study reported top-line results in 1020 knee-OA
      patients in September 2008. In addition to meeting the three co-primary
      endpoints at 13 weeks (p<0.001), both doses of naproxcinod (750 mg and
      375 bid) were statistically non-inferior to naproxen 500 mg bid at 26
      weeks, in terms of the mean change from baseline in the WOMAC(TM) pain
      and function subscales.

    - Top-line results from the 303 study in 810 patients with OA
      of the hip were reported in November. Naproxcinod 750 mg bid met all
      three co-primary efficacy endpoints with high statistical significance
      (p<0.001).

During 2008, NicOx successfully completed an extensive database describing naproxcinod's blood pressure profile in more than 3,000 patients, using Office Blood Pressure Measurements (OBPM) and Ambulatory Blood Pressure Monitoring (ABPM).

Naproxcinod shows positive blood pressure results in phase 3 pooled analysis

In December 2008, NicOx announced the top-line results of the pooled blood pressure analysis from the phase 3 program (304). OBPM measurements were taken in a rigorous and standardized manner in each of the pha
'/>"/>

SOURCE NicOx
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15

Related biology technology :

1. Arpida Announces Full Year 2008 Financial Results
2. Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results
3. ViroPharma Incorporated Reports Fourth Quarter and Full Year 2008 Financial Results
4. American Oriental Bioengineering, Inc. to Report Fourth Quarter and Full Year 2008 Financial Results on March 9, 2009
5. Frontage Laboratories Continues to Grow Its China Business and Add Corporate Financial, Regulatory and Clinical Pharmacology Talent
6. InterMune to Release Fourth Quarter, Full Year 2008 Financial Results on February 26
7. CV Therapeutics Reports 2008 Fourth Quarter and Full Year Financial Results
8. Human Genome Sciences to Sponsor Conference Call to Discuss Full Year 2008 Financial Results
9. Adolor Corporation to Host Investor Conference Call to Report 2008 Financials and Provide an Update on the Launch of ENTEREG(R) (alvimopan)
10. BioMarin Announces Fourth Quarter and Full Year 2008 Financial Results
11. Senesco Technologies Reports Second Quarter Fiscal 2009 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... China , 22 juli 2014 BGI ... BGI, ,s wereld grootste organisatie op het gebied van ... service ten behoeve van hele menselijke genoomsequentie via het ... In 2013 acquireerde BGI Complete Genomics, ... staat vanwege de in eigen beheer ontwikkelde sequentietechnologieën met ...
(Date:7/22/2014)...  Semler Scientific, Inc. (Nasdaq: SMLR ... that develops patented products that assist healthcare providers ... announced that it will report second quarter 2014 ... markets on July 25, 2014. Doug Murphy-Chutorian, M.D., chief executive ... at 11 a.m. EDT, July 25, 2014. The ...
(Date:7/22/2014)... Los Angeles, CA (PRWEB) July 22, 2014 ... rapid test solutions with the debut of its ... Association of Clinical Chemistry (AACC) meeting in Chicago, ... based or bench top versions, the HRDR-300 is ... patent pending technology to analyze fluorescent lateral flow ...
(Date:7/22/2014)... Dr. Williams says, “Bush has joined the ... the greatest health care system in the world is ... while trying to serve the public. Unfortunately, Bush has ... an enormous system that none of them can first ... series of Open Letters ( http://is.gd/wdU2CM ) provides a ...
Breaking Biology Technology:BGI Tech introduceert service op gebied van hele menselijke exoomsequencing op geavanceerd Complete Genomics-platform 2Semler to Report Second Quarter 2014 Financial Results and Host Conference Call on July 25, 2014 2Holomic to Debut HRDR-300 Fluorescent Immunoassay Reader at the AACC 2014 2Dr. Ira Williams Asks What’s Wrong With Jonathan Bush’s Book, Where Does It Hurt? 2
... , ... changes expected at the FDA, including increased scrutiny of complex medical devices, automating your ... from Full Spectrum Software, one of the leading medical device software engineering and QA ... implement QA automation. , ...
... University (URV) in Tarragona has developed a biosensor that can ... the bacteria that causes typhoid fever. The technique uses carbon ... when they link up with the pathogen. "We have ... of bacteria immediately, easily and reliably", F. Xavier Rius, lead ...
... , , , ... NBIX ) announced today that the Company has entered into a Committed ... Under the terms of the agreement, Kingsbridge has committed to provide up ... discretion, through the purchase of newly-issued shares of Neurocrine common stock. ...
Cached Biology Technology:Implementing QA Automation Tools in an FDA Controlled Software Environment, a Free Webinar 2New biosensor can detect bacteria instantaneously 2Neurocrine Biosciences Secures Committed Equity Financing Facility 2Neurocrine Biosciences Secures Committed Equity Financing Facility 3
(Date:7/22/2014)... recent scientific discovery showed that mutations in prickle ... brain disorder characterized by repeated seizures over time. ... was unknown. , A new University of Iowa ... Proceedings of the National Academy of Sciences , ... epilepsy. UI researchers have identified the basic cellular ...
(Date:7/22/2014)... might not be good for the average steak, but ... they prepare to survive Alaska,s winter cold. , "Alaska ... than a steak does in your freezer and the ... better shape than the steak," said Don Larson, University ... a recent paper demonstrating that freeze tolerance in Alaska ...
(Date:7/22/2014)... that examined the survival rates of 12 different ... longline fishing operations found large differences in survival,rates ... and scalloped hammerhead being the most,vulnerable. The study, ... (UM) Rosenstiel School of,Marine and Atmospheric Science and ... provides,new information to consider for future conservation measures ...
Breaking Biology News(10 mins):UI study finds potential genetic link between epilepsy and neurodegenerative disorders 2Alaska frogs reach record lows in extreme temperature survival 2Alaska frogs reach record lows in extreme temperature survival 3New study reveals vulnerability of sharks as collateral damage in commercial fishing 2
... forms of protozoons, the oocysts from the Cryptosporidium ... one of the greatest public health problems in water supply, ... Jos Antonio Castro Hermida, a scientist at the Galician Institute ... tells SINC. A team led by this researcher took ...
... announced that it has secured a license agreement for ... Energy Lab at Wayne State University. The ... of catalysts that enable biodiesel producers to use cost-effective ... and residual corn oil, and convert them into biodiesel. ...
... new dinosaur named Brontomerus mcintoshi , or "thunder-thighs" after its ... new species is described in a paper recently published in the ... scientists from the U.K. and the U.S. A member ... and Brachiosaurus , Brontomerus may have used ...
Cached Biology News:Parasitic protozoons survive waste water and drinking water treatment plants in Galicia 2NextCAT secures license agreement for advanced biofuel technology from Wayne State 2New 'thunder-thighs' dinosaur discovered 2New 'thunder-thighs' dinosaur discovered 3
Borosilicate Glass. Certified for use with the Beacon 2000 Systems, 1,000 tubes/case...
... Engineered with new technology incorporating ... for unsurpassed flexibility, the new Varian ... advanced spectrometer available today., ,The Varian ... each transmitter and receiver channel, providing ...
Luminometers...
... Dr. P Set from different ... More organs maybe available upon ... two items from the whole set, ... set price. All Dr. P ...
Biology Products: