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Fat droplet nanoparticle delivers tumor suppressor gene to tumor and metastatic cells
Date:4/20/2009

d around the gene simply melts away, unlike non-biodegradable delivery systems.

Clinical trials are now underway at the Mary Crowley Medical Research Center, affiliated with Baylor University at Dallas, under the direction of clinical trial principal investigator Dr. John Nemunaitis. The trial already has enrolled six patients with various cancers and anticipates a total of 14. Early results are promising, says Dr. Chang. In addition to evaluating the safety issues for which phase 1 trials are designed, investigators are seeing anti-tumor efficacy. Dr. Chang says she is hopeful that the gene therapy will become a first line treatment that will significantly reduce the probability of recurrent tumors.


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Contact: Sylvia Wrobel
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Federation of American Societies for Experimental Biology
Source:Eurekalert

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