Navigation Links
FDA's Oncologic Drugs Advisory Committee to Review Resubmitted Pixantrone New Drug Application on February 9, 2012
Date:1/2/2012

s on anthracycline-like agents that are responsible for the generation of oxygen free radicals and the formation of toxic drug-metal complexes have also been modified in pixantrone in an effort to prevent the binding of iron and perpetuation of superoxide production -- both of which are the putative mechanism for anthracycline induced acute cardiotoxicity. These novel pharmacologic differences may allow re-introduction of anthracycline-like potency in the treatment of relapsed/refractory diffuse large lymphoma without unacceptable rates of cardiotoxicity.

About Cell Therapeutics, Inc.

Headquartered in Seattle, CTI is a biopharmaceutical company committed to developing an integrated portfolio of oncology products aimed at making cancer more treatable. For additional information, please visit www.CellTherapeutics.com http://www.CellTherapeutics.com.

Sign up for email alerts and get RSS feeds at our Web site, http://www.CellTherapeutics.com/investors_alert

This press release includes forward-looking statements that involve a number of risks and uncertainties the outcome of which could materially and/or adversely affect actual future results and the market price of CTI's securities. Specifically, the risks and uncertainties that could affect the development of pixantrone include risks associated with preclinical and clinical developments in the biopharmaceutical industry in general, and with pixantrone in particular, including, without limitation, the potential failure of pixantrone to prove safe and effective for the treatment of relapsed or refractory NHL and/or other tumors as determined by the FDA and/or the EMA, that accelerated approval by the FDA of pixantrone may not occur, that CTI may not be able to address satisfactorily the two key matters raised by the ON
'/>"/>

SOURCE Cell Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. MarketsandMarkets: Lung Cancer Drugs Market in G7 Countries Worth $13 Billion by 2020
2. Malaria discovery gives hope for new drugs and vaccines
3. Permeon reveals discovery of Intraphilins as new approach to intracellular biologic drugs
4. Reportlinker Adds Innovations in Protein Kinase Therapies - Significant Proportion of Protein Kinase Pipeline Contains Small Molecule Drugs That Target Oncology
5. UCLA scientists discover new way to wake up the immune system using nano vaults to deliver drugs
6. Zacharon Pharmaceuticals Announces Research and Development Collaboration With Pfizer to Develop Drugs for Multiple Rare Disorders
7. Ontario Institute for Cancer Research Announces Investment in Microfluidics Technology for the Discovery of Anti-Cancer Drugs
8. Reportlinker Adds Biologic Therapeutic Drugs: Technologies and Global Markets
9. Isis Pharmaceuticals Adds Two New Drugs to Development Pipeline
10. Reportlinker Adds Emerging Opportunities in Biosimilar and Biobetter Drugs Markets
11. Reportlinker Adds Financial Health of Biotechnology and Drugs Industry in India and China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... JH Technologies announces the ... Irvine. JH Technologies, a leader in sales and ... an expanded partnership with Leica Microsystems into the Southern ... analysis solutions will be featured at the grand opening ... showroom facility is located within the JH Technologies office’s ...
(Date:9/17/2014)... 17, 2014 Terracon Corporation has announced ... TerraPure tank . This addition to the company’s ... FDA-compliant linear polyethylene and available in 125 or 250 ... ships in two weeks or less. , The new ... found in Terracon’s existing TerraPure tank line – plus ...
(Date:9/17/2014)... 17, 2014 Alternative Fuels Americas, Inc. (AFAI) announced ... Special Purpose Vehicle in partnership with Jatro Greentech, Inc., a ... company. The SPV shall be called AFAI Jatro Green Ethiopia ... majority shareholder. The SPV shall pursue Jatropha planting and biofuels ... Ethiopia . "Although we have ...
(Date:9/17/2014)... RXi Pharmaceuticals Corporation (NASDAQ: ... developing and commercializing innovative therapies addressing major unmet ... has been granted a patent by the United ... delivery system for delivering its "original" RNAi compounds ... treatment of diseases with an inflammatory component. Potential ...
Breaking Biology Technology:JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 2JH Technologies displays newest microscope imaging technology at Southern California showroom grand opening 3Terracon Introduces Pre-Engineered TerraPure® Tank for Ultrapure Water Applications 2AFAI Signs Joint Venture Agreement With Jatro Greentech Inc. 2AFAI Signs Joint Venture Agreement With Jatro Greentech Inc. 3RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 2RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 3RXi Pharmaceuticals Strengthens Intellectual Property Portfolio 4
... The world,s smallest chess board about the diameter ... were winners in this year,s design contest for, respectively, ... National Laboratories in mid May. The two winning ... facility, one of the most advanced in the world. ...
... Corgenix Medical Corporation (OTC Bulletin Board: CONX), a worldwide developer ... its AspirinWorks® Test June 17-19 at the Pri-Med New York ... Convention Center in New York, N.Y. , ... Corgenix representatives will be on-hand during the conference ...
... New data from a retrospective cohort study showed that up ... (GID) that can have a substantial adverse effect on major PD-related clinical ... Congress of Parkinson,s Disease and Movement Disorders in Buenos Aires, Argentina ... , , ...
Cached Biology Technology:Texas Tech, U of Utah win Sandia microdevice competition 2Texas Tech, U of Utah win Sandia microdevice competition 3Texas Tech, U of Utah win Sandia microdevice competition 4Corgenix to Exhibit AspirinWorks(R) Test at Pri-Med New York 2Corgenix to Exhibit AspirinWorks(R) Test at Pri-Med New York 3New Study Showed the Impact of Gastrointestinal Disorders in Patients With Parkinson's Disease 2New Study Showed the Impact of Gastrointestinal Disorders in Patients With Parkinson's Disease 3New Study Showed the Impact of Gastrointestinal Disorders in Patients With Parkinson's Disease 4
(Date:9/16/2014)... have discovered the "molecular brakes" that time the generation ... mice. These "hair cells" translate sound waves into electrical ... interpreted as sounds. If the arrangement of the cells ... of the research will be published in The ... proteins Hey1 and Hey2 act as brakes to prevent ...
(Date:9/16/2014)... inherit certain traits from our parents that are pre-determined. ... play out by taking certain drugs or better yet, ... team of researchers at the Boston University School of ... research. , Epigenetics regulates gene expression in a ... which prevent permanent mutations or alterations within the gene ...
(Date:9/16/2014)... species has its own bacterial identity. That,s the conclusion ... institutions who studied the genetic fingerprints of bacteria on ... , "This study demonstrates for the first time that ... ecological strategies possess very different microbial communities on their ... postdoctoral researcher in the UO,s Institute of Ecology and ...
Breaking Biology News(10 mins):Hey1 and Hey2 ensure inner ear 'hair cells' are made at the right time, in the right place 2Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 2Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 3Microbiome research shows each tree species has a unique bacterial identity 2
... Future of the Nuclear Industry" will be the Plenary Session topic ... taking place June 28-July 1, 2010, at the Salt Palace Convention ... Chair of the Nuclear Regulatory Commission, will be the lead presenter ... Over 250 presentations between June 28 and July 1 will occur ...
... been established for more than 50 years as one ... termed bipolar disorder. However, scientists have never been ... new research from Cardiff University scientists suggests a possible ... better understanding of the illness and potentially more effective ...
... bacteria lead oil companies to change their methods of harvesting ... reducing the carbon dioxide that burning oil and gasoline discharges ... Larter, professor of geoscience and holder of the ... Calgary, was the keynote speaker today for the 2010 Goldschmidt ...
Cached Biology News:55th annual meeting of the Health Physics Society 2
...
...
... The pCITE-2a-c(+) vectors are designed for enhanced translation ... extracts, e.g. rabbit reticulocyte lysate. The maps for ... with the following exceptions: pCITE-2b(+) is a 3793 ... BstX I and Xcm I sites. Subtract 7 ...
...
Biology Products: