Navigation Links
FDA Grants Soligenix Orphan Drug Designation for SGX94 for Treatment of Acute Radiation Syndrome
Date:9/16/2013

ng exclusivity that orphan drug designation imparts adds significantly to the existing patent estate surrounding SGX94." 

About ARS

ARS occurs after toxic radiation exposure and involves several organ systems, notably the skin, the bone marrow and the gastrointestinal (GI) tract.   In the event of a nuclear disaster or terrorist detonation of a nuclear bomb, casualties exposed to >2 Gy are at high risk for development of clinically significant ARS. The chance of survival for people with ARS decreases with increasing radiation dose, with doses of 10-12 Gy causing death within 15 days and lower doses potentially causing death within a few months. The cause of death within 15 days of radiation exposure is usually damage to the GI tract whereas after 15 days death usually is a consequence of bone marrow (hematopoietic) injury. Symptoms of cutaneous (skin) radiation injury are recurring phenomena after ARS.  For the survivors, the recovery process may last from several weeks up to two years. Although the hematopoietic syndrome may be rescued by bone marrow transplantation or growth factor administration, the risk of death due to infection remains very high.  There is currently no established treatment or preventive measure for the GI damage that occurs after high-dose radiation.

About SGX94

SGX94 is an IDR, a new class of short, synthetic peptides that has a novel mechanism of action in that it has simultaneous anti-inflammatory and anti-infective activity.  IDRs have no direct antibiotic activity but modulate host responses, increasing survival after infections with a broad range of bacterial Gram-negative and Gram-positive pathogens, as well as accelerating resolution of tissue damage following exposure to a variety of agents including bacterial pathogens, trauma and chemo- and/or radiation-therapy.  SGX94 has demonstrated safety in a Phase 1 clinical study in healthy human volunteers and efficacy in n
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Crowdfunding Expert Kendall Almerico Discusses Scientists Using Crowdfunding to Replace Research Grants
2. Hovione: EPO Grants a New Inhaler Patent
3. Proposals Now Being Accepted for the 2014 Pittsburgh Conference Memorial National College Grants (PCMNCG)
4. Transposagen Receives Over $4.3M in Grants and Investment
5. Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants
6. U.S. FDA Grants Fast-Track Designation to Sanofi Pasteur and KaloBios Novel Biologic Candidate for Pseudomonas aeruginosa
7. R&D Systems is Offering Travel Grants to Attend the 15th International Congress of Immunology
8. Cellular Dynamics and Coriell Institute for Medical Research Awarded Multi-Million Dollar Grants from California Institute for Regenerative Medicine to Manufacture and Bank Stem Cell Lines
9. Hadasit Bio-Holdings Ltd. Portfolio Companies - ProtAb Ltd. and KAHR Medical Ltd. to Receive NIS 10.7 Million (Over $2.8 Million USD) in Additional Government Grants
10. Immunology 2013™ Travel Grants Available from R&D Systems
11. SomaGenics Announces Issue of Key Patent for Its sshRNA Technology and Receipt of Two New Small Business Innovation NIH Grants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... A new research platform uses a laser ... structures undergoing stress and heating, an approach ... for microelectronics and batteries., This new technique, ... how heating and the surface stress of ... have discussed the merits of surface-stress influence ...
(Date:8/28/2014)... --  SunTrust Robinson Humphrey (STRH) today announced ... equity research team in biotechnology and oilfield services.  ... research demonstrates our commitment to providing our valued ... investment decision making," said Biff Woodruff , ... make significant investments in differentiated content at a ...
(Date:8/28/2014)... Woodstock, Vt. (PRWEB) August 28, 2014 ... microbiology testing around the world is available from ... industrial diagnostics companies. “ Industrial Microbiology Market Review, ... the Industrial Market ” (IMMR—4) tracks and compares ... in in North America, Europe and Asia, and ...
(Date:8/27/2014)... Lake City, Utah (PRWEB) August 27, 2014 ... construction that will expand its current Salt Lake City ... currently underway outside of Utah to ultimately create 1,000 ... next 20 years. , “Utah is home to ... of whom can be credited with Varian’s success in ...
Breaking Biology Technology:New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 2SunTrust Robinson Humphrey Expands Equity Research in Healthcare and Energy 32 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 3
... Impact on Families of von ... Willebrand Disease, NEW YORK, ... most common hereditary bleeding disorder, von,Willebrand disease (VWD), most don,t even know ... Centers for Disease Control and,Prevention (CDC) it takes a woman an average ...
... DIEGO, Sept. 23 Halozyme Therapeutics,Inc. (Nasdaq: ... targeting the extracellular matrix, today,announced that Douglas B. ... Endocrinology Clinical Development., "I am thrilled to ... achievement to the Halozyme leadership team. He is ...
... 85,000 Expected to Enroll in Phase 4 Study ... Wyeth Pharmaceuticals, a,division of Wyeth (NYSE: WYE ... Pneumonia Immunization Trial in Adults a major study ... to help,prevent pneumococcal pneumonia -- the leading cause ...
Cached Biology Technology:Video: Moms Raise 'Red Flag' About the Dangers of Widely Undiagnosed Bleeding Disorder 2Video: Moms Raise 'Red Flag' About the Dangers of Widely Undiagnosed Bleeding Disorder 3Video: Moms Raise 'Red Flag' About the Dangers of Widely Undiagnosed Bleeding Disorder 4Halozyme Therapeutics Appoints Head of Endocrinology Clinical Development 2Halozyme Therapeutics Appoints Head of Endocrinology Clinical Development 3Halozyme Therapeutics Appoints Head of Endocrinology Clinical Development 4Major Adult Vaccine Clinical Trial for Pneumonia Prevention Begins 2Major Adult Vaccine Clinical Trial for Pneumonia Prevention Begins 3Major Adult Vaccine Clinical Trial for Pneumonia Prevention Begins 4Major Adult Vaccine Clinical Trial for Pneumonia Prevention Begins 5
(Date:8/28/2014)... A Mayo Clinic researcher and his collaborators have developed ... enhance the process of re-engineering cells for biomedical investigation. ... biology methods to aid stem cell engineering. Details of ... described in two back-to-back papers in the journal ... range of uses for all types of cell-based investigations ...
(Date:8/28/2014)... , Aug. 28, 2014  Privacy Advocate and ... Jennifer Lynch , joins the lineup of biometric ... second annual Biometrics UnPlugged Executive Summit in ... Previously announced speakers include Steven Rahman, Director, Technology ... Public Sector at Experian. The theme of this year,s ...
(Date:8/28/2014)... the most commonly diagnosed learning disability in the ... occurs when the regions of the brain that ... use of non-invasive functional neuroimaging tools has helped ... However, most prior work has focused on only ... gap in our understanding of how multiple brain ...
Breaking Biology News(10 mins):New tool aids stem cell engineering for medical research 2Biometrics UnPlugged Welcomes the Electronic Frontier Foundation's Jennifer Lynch to the Mobility at the Crossroads of Commerce and Privacy Summit 2Dyslexic readers have disrupted network connections in the brain 2
... clams to flying creatures like hummingbirds and bats, many ... flow. When the 61st Annual Meeting of the American ... from November 23-25 at the San Antonio Convention Center, ... with applications in astronomy, engineering, alternative energy, biology, and ...
... University] Imagine yourself swimming in a pool: It,s the ... the water, that mostly dictates the speed and direction that ... Microbes, speed and direction are subjected more to the physical ... swim in water," explained Jay Tang, associate professor of physics ...
... land use patterns and increasing pressures on water ... management focuses on regulating the flow of runoff ... the hydrologic cycle disrupted by extensive pavement and ... of infiltration opportunities affects groundwater recharge and has ...
Cached Biology News:Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 2Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 3Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 4Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 5Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 6Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 7Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25 8How do bacteria swim? Brown physicists explain 2Urban trees enhance water infiltration 2
... GenomePlex Single Cell Whole Genome Amplification ... on random fragmentation of genomic DNA ... fragments to PCR-amplifiable library molecules flanked ... achieved by PCR amplification of the ...
...
From formula-fed bovine calves Sterile, Cell culture tested...
Collected at a certified USDA establishment located within the United States. All final processing is done by Quad Five employees....
Biology Products: