Navigation Links
FDA Grants Priority Review for Schering-Plough's Peginterferon Alfa-2b for the Adjuvant Treatment of Patients With Stage III Melanoma
Date:1/31/2008

e mild (44%) or moderate (4%) and no patient discontinued, and included injection site inflammation and reaction (ie, bruise, itchiness, irritation). Injection site pain was reported in 2% of patients receiving PEGINTRON(TM). Alopecia (thinning of the hair) is also often associated with alpha interferons including PEGINTRON(TM).

Psychiatric adverse events, which include insomnia, were common (57%) with PEGINTRON(TM) but similar to INTRON(R) A (58%). Depression was most common at 29%. Suicidal behavior including ideation, suicidal attempts, and completed suicides occurred in 1% of patients during or shortly after completing treatment with PEGINTRON(TM).

The following serious or clinically significant adverse events have been reported at a frequency less than or equal to 1% with PEGINTRON(TM) or interferon alpha: Severe decreases in neutrophil or platelet counts, hypothyroidism, hyperglycemia, hypotension, arrhythmia, ulcerative and hemorrhagic colitis, development or exacerbation of autoimmune disorders including thyroiditis, RA, systemic lupus erythematosus, psoriasis, pulmonary disorders (dyspnea, pulmonary infiltrates, pneumonitis and pneumonia, some resulting in patient deaths), urticaria, angioedema, bronchoconstriction, anaphylaxis, retinal hemorrhages, and cotton wool spots.

Additional Safety Information

Relapse of drug addiction/overdose has occurred in patients on PEGINTRON(TM) therapy. Aggressive behavior sometimes directed towards others has occurred in patients with and without a previous psychiatric disorder during PEGINTRON(TM) and/or INTRON(R) A treatment and follow-up.

If patients develop psychiatric problems, including clinical depression, it is recommended that patients be carefully monitored during treatment and in the 6-month follow-up period. If psychiatric symptoms persist or worsen, or suicidal ideation or aggressive behavior towards others is identified, it is recommended that treatment with PEGINTRON(TM) and
'/>"/>

SOURCE Schering-Plough Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Mirus Bio Awarded Grants & Contracts of Over $5 Million
2. FDA Grants Orphan Drug Designation to TREANDA, an Investigational Treatment for Chronic Lymphocytic Leukemia
3. Anesiva Grants Specific-Use License of Its Needle-Free Drug Delivery Technology to Particle Therapeutics for Diabetes Drug
4. NIH grants $750,000 to develop device to determine temperature of neonates brain
5. Edwards Lifesciences Grants UC Irvine $5 Million to Establish the Edwards Lifesciences Center for Advanced Cardiovascular Technology
6. Radius Grants Major Pharmaceutical Company Exclusive Option to License BA058 for Osteoporosis
7. Poniard Pharmaceuticals Announces European Commission Grants Orphan Medicinal Product Designation to Picoplatin for Treatment of Small Cell Lung Cancer
8. CV Therapeutics Reports Option Grants Under Nasdaq Marketplace Rule 4350
9. NASDAQ Panel Grants Merge Technologies Additional Time to Regain Compliance
10. FDA Grants Resverlogix Approval to Commence a Phase 1 Clinical Trial for RVX-208
11. Maryland Stem Cell Commission Issues Nationwide Request for Applications for New Post-Doctoral Fellowship Grants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2015)... BerGenBio AS ("BerGenBio" or the ... abstract on the latest data on BGB324, the Company,s ... tyrosine kinase, and BGB10C9, an Axl function-blocking monoclonal antibody ... conjunction with the 2015 American Society of Clinical Oncology ... May 29 - June 2, 2015. The ...
(Date:5/29/2015)... The Academy of Model Aeronautics has ... graduates from across the nation. , The Academy of ... AMA Youth Members with scholarships to pursue technical careers. ... has awarded nearly $900,000 to college-bound aero-modelers. The scholarships ... and individuals, AMA member donations, a portion of AMA ...
(Date:5/29/2015)... May 29, 2015 Market Publishers ... ) signed a partnership agreement for quality market ... to distribute and sell research reports worked out ... Partners Department, commented upon the agreement: “Chem-Report is ... key petroleum and chemical markets on global and ...
(Date:5/29/2015)... When a leading manufacturer of ... to design an industrial oven that ... being produced using a 3D-printing process, Gruenberg engineers ... gantry, heat-saving windows, and internal actuators and sensors ... pills to exact specifications. , To ensure the ...
Breaking Biology Technology:BGB324 and BGB10C9 Show Promise in Models of Pancreatic Cancer 2BGB324 and BGB10C9 Show Promise in Models of Pancreatic Cancer 3Academy of Model Aeronautics Awards $46,500 in Scholarships to College-Bound Model Aviation Pilots 2Market Publishers Ltd and Chem-Report Sign Partnership Agreement 2Market Publishers Ltd and Chem-Report Sign Partnership Agreement 3New industrial oven with “pill pushing” robotic gantry precisely removes excess moisture from 3D-printed pharmaceuticals 2
... Technology Can Solve Pressing Food, Fuel Problems of ... ON, Dec. 3 /PRNewswire/ - Dr. David Dennis, FRSC, CEO of ... at a side event at the United Nations Climate Change Conference ... solved global problems in the 20th Century and the role it ...
... DEERFIELD, Ill., Dec. 3 Today, the International Society,for ... stem cell researchers, released new guidelines for the responsible,development ... A,Commentary article that summarizes the Guidelines for the ... Press in the December issue of Cell,Stem Cell, the ...
... VIENNA, Va., Dec. 3 In response to numerous,shareholder ... it has added updated pictures of it new manufacturing ... CEL-SCI,s homepage,( http://www.cel-sci.com ) by clicking on the link ... , CEL-SCI is ...
Cached Biology Technology:Leading Canadian Scientist to speak at UN Climate Change Conference 2The International Society for Stem Cell Research Releases New Guidelines to Shape Future of Stem Cell Therapy 2The International Society for Stem Cell Research Releases New Guidelines to Shape Future of Stem Cell Therapy 3The International Society for Stem Cell Research Releases New Guidelines to Shape Future of Stem Cell Therapy 4
(Date:5/11/2015)... 11, 2015 Curemark LLC, a privately held ... a new Phase III double blind, randomized, placebo-controlled clinical ... CM-AT, on all children ages 3-8 with Autism. Previously, ... III double blinded clinical trial for CM-AT in children ... the digestive enzyme chymotrypsin. This new trial will help ...
(Date:5/5/2015)... , May 5, 2015, NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, reminds investors ... Chief Technology Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA ... 5-7, 2015. The three-day conference is organized ... is speaking in is themed Global Fraud: Where is ...
(Date:4/20/2015)... 2015 Huntington Memorial Hospital is the first ... new miniaturized, wireless monitoring sensor to manage heart failure ... only FDA-approved heart failure monitoring device that has been ... physicians to manage heart failure. The CardioMEMS ... the pulmonary artery (PA) during a non-surgical procedure to ...
Breaking Biology News(10 mins):Curemark, LLC, Launches New Phase III Trial in Expanded Population of Children with Autism 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3
... - Coding variants in immune disease-related genes play only ... psoriasis, according to a new study led by Anhui ... by their investigation on the contribution of functional coding ... a large-scale investigation, researchers only discovered two independent low-frequency ...
... Baltimore, MD November 9, 2013 New research ... Americans with chronic kidney disease contribute to a more ... The research, led by investigators from the University of ... help explain, in part, why even after accounting for ...
... other devices that can change shape or move with ... may be possible through research led by the University ... when triggered by light, thereby converting light energy into ... machine components such as switches and power sources. ...
Cached Biology News:The contribution of coding variants to psoriasis much smaller than thought 2Genetic variation increases risk of kidney disease progression in African-Americans 2Genetic variation increases risk of kidney disease progression in African-Americans 3Genetic variation increases risk of kidney disease progression in African-Americans 4Snap to attention: Polymers that react and move to light 2
Sheep polyclonal to Quinolone ( Abpromise for all tested applications). Antigen: Norfloxacin(N)conjugated to BSA...
DONOR BOVINE SERUM AND PLASMA...
The Magnetic Separation Rack is designed to be used for small-scale separations using magnetic particles. ,Capacity: 6 microcentrifuge tubes....
5(S)-HETE-d8 is used as an internal standard for the quantification of 5(S)-HETE by stable isotope dilution mass spectrometry....
Biology Products: