Navigation Links
FDA Grants Priority Review for Schering-Plough's Peginterferon Alfa-2b for the Adjuvant Treatment of Patients With Stage III Melanoma
Date:1/31/2008

growths. Interferon alfa-2b has similar actions to natural interferon. Pegylated interferon alfa-2b is a longer-acting form of interferon made by attaching an inert molecule called polyethylene glycol, or PEG, to the alpha interferon molecule. This modification increases the size of the interferon molecule and results in slower elimination from the body, allowing for less frequent dosing than required for standard interferon.

Peginterferon alfa-2b is not approved for treatment of melanoma. In the United States, peginterferon alfa-2b, marketed as PEGINTRON(TM), is indicated for use alone or with ribavirin for the treatment of chronic hepatitis C in patients with compensated liver disease who have not been previously treated with interferon alpha and who are at least 18 years of age.

In the EU, peginterferon alfa-2b and ribavirin combination therapy is approved for the treatment of chronic hepatitis C who have elevated transaminases without liver decompensation and who are positive for serum HCV-RNA or anti-HCV, including naive patients with clinically stable HIV co-infection and in patients who have failed previous treatment with interferon alpha (pegylated or nonpegylated) and ribavirin combination therapy or interferon alpha monotherapy. Peginterferon alfa-2b had previously received centralized marketing authorization and is marketed as a monotherapy in cases of intolerance or contraindication to ribavirin for the treatment of adult patients with chronic hepatitis C.

In the malignant melanoma trial and other clinical studies, patients receiving peginterferon alfa-2b experienced mild-to-moderate or severe/life-threatening side effects. The most common side effects of peginterferon alfa-2b are: flu-like symptoms, including headache, fatigue, aches and pains, fevers and chills; depression, nausea, loss of appetite and diarrhea; insomnia; alopecia (hair loss); a reaction at the site of injection; changes in blood liver function tests and in blood c
'/>"/>

SOURCE Schering-Plough Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Mirus Bio Awarded Grants & Contracts of Over $5 Million
2. FDA Grants Orphan Drug Designation to TREANDA, an Investigational Treatment for Chronic Lymphocytic Leukemia
3. Anesiva Grants Specific-Use License of Its Needle-Free Drug Delivery Technology to Particle Therapeutics for Diabetes Drug
4. NIH grants $750,000 to develop device to determine temperature of neonates brain
5. Edwards Lifesciences Grants UC Irvine $5 Million to Establish the Edwards Lifesciences Center for Advanced Cardiovascular Technology
6. Radius Grants Major Pharmaceutical Company Exclusive Option to License BA058 for Osteoporosis
7. Poniard Pharmaceuticals Announces European Commission Grants Orphan Medicinal Product Designation to Picoplatin for Treatment of Small Cell Lung Cancer
8. CV Therapeutics Reports Option Grants Under Nasdaq Marketplace Rule 4350
9. NASDAQ Panel Grants Merge Technologies Additional Time to Regain Compliance
10. FDA Grants Resverlogix Approval to Commence a Phase 1 Clinical Trial for RVX-208
11. Maryland Stem Cell Commission Issues Nationwide Request for Applications for New Post-Doctoral Fellowship Grants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... July 28, 2014 Research and Markets ... Synthetic Biology Market 2014-2018" report to their offering. ... The term synthetic biology covers the designing and engineering ... well as the redesigning of natural biological systems that ... be a form of extreme genetic engineering because it ...
(Date:7/28/2014)... 28, 2014 According ... Market by Products (Consumables, Instruments, Services), Methods (Phenotypic, Genotypic), Applications (Pharmaceutical, ... (Detection, Characterization) - Global Forecasts to 2019" ... is estimated at $896.5 Million in 2014 ... by 2019, growing at a CAGR of ...
(Date:7/28/2014)... Boston, MA (PRWEB) July 28, 2014 ... with two researchers to further develop potential treatments for ... brain tumor, in combination with their patented vaccine platform, ... and Duke University, are based on the work of ... of Neurosurgery at The Preston Robert Tisch Brain Tumor ...
(Date:7/28/2014)... St Louis, MO (PRWEB) July 28, 2014 ... tools, software, and services that bring the power of ... for the inaugural Appistry Pipeline Challenge . ... Callum Bell, president of the National Center for Genome ... Children’s Mercy Hospitals and Clinics of Kansas City. Rounding ...
Breaking Biology Technology:Global Synthetic Biology Market 2014-2018 2Microbial Identification Market worth $1,194.1 Million by 2019 2Microbial Identification Market worth $1,194.1 Million by 2019 3String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 2String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 3String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 4Appistry Names Industry Experts from the National Center for Genome Resources and Mercy Children's, Kansas City, to Judge Pipeline Challenge Competition 2
... Because I used to be a corporate HR person, people ask me ... question that I get asked is: Can my company actually do that? ... did anyway. , ,Im not a lawyer. I dont send people off ... so far). Life is long. So many of these errors are clueless ...
... moved to speed up information access for officers, with the ... Aladdin Knowledge Systems . , ,It has proven to provide ... officers, who are now free to focus on protecting the ... information, said Neil Sullivan, the companys enterprise security regional manager. ...
... Stem Cell MADISONIn the first debate of Wisconsin's ... scientific research using human embryonic stem cells as little ... the 99 percent of stem cell research that uses ... the 1 percent that uses human embryonic stem cells. ...
Cached Biology Technology:Illegal business tricks: Can my company do that? 2Illegal business tricks: Can my company do that? 3Madison police adopt digital lock and key 2It's 99 percent certain: Research cannot rely on adult stem cells alone 2It's 99 percent certain: Research cannot rely on adult stem cells alone 3
(Date:7/28/2014)... of the top 10 U.S. cities that have seen ... inconveniences as frequent road closures, overwhelmed storm drains and ... new NOAA technical report. , This nuisance flooding, caused ... U.S. coasts, between 300 and 925 percent since the ... Flood Frequency Changes around the United States, also finds ...
(Date:7/28/2014)... Jude Children,s Research Hospital study found that 73 percent ... their risk of developing metabolic syndrome and related health ... results appear in the current issue of the journal ... 1,598 adult survivors of childhood cancer in the study ... factors like high blood pressure, abdominal obesity, elevated triglyceride ...
(Date:7/28/2014)... body,s natural virus killers to prevent and treat HIV ... strong inflammatory response these molecules can arouse as they ... by scientists at the Weizmann Institute and the National ... activity of these molecules interferons around the ... course of the disease. Their research appeared in ...
Breaking Biology News(10 mins):NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 2Unhealthy habits more than double risk of metabolic syndrome in childhood cancer survivors 3Interfering with interferon 2
... of the biological effects of Antarctic icebergs shows that they ... take up carbon dioxide from the atmosphere and then, through ... process is detailed in 19 new research papers published electronically ... Research Part II: Topical Studies in Oceanography . The ...
... Applied Ecology received EPA funding to develop a design-feasibility ... The study, being done in collaboration with Clemson,s ... Development and the city of Charleston, will evaluate the ... farm, powering it with solar and wind energy and ...
... marine species at or near the top of their ... bodies when they live and feed in waters near ... Marine Laboratory (HML), a government-university collaboration in Charleston, S.C. ... Environmental Science & Technology , one research team ...
Cached Biology News:Antarctic icebergs help the ocean take up carbon dioxide 2Antarctic icebergs help the ocean take up carbon dioxide 3Clemson University institute to study 'vertical farming' feasibility in Charleston, S.C. 2Clemson University institute to study 'vertical farming' feasibility in Charleston, S.C. 3Marine lab research tracks pollutants in dolphins and beluga whales 2Marine lab research tracks pollutants in dolphins and beluga whales 3