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FDA Clears New Applicators for Endometrial Cancer Treatment With Xoft's Axxent(R) Electronic Brachytherapy System
Date:5/21/2008

ndorsed the recommendations made by the National Comprehensive Cancer Network for the use of brachytherapy in the treatment of endometrial cancer and has issued specific guidelines for technique as well as the application of brachytherapy.

"Accelerated treatment of breast cancer using Electronic Brachytherapy has been very well received by our patients and we are very excited to be able to offer the benefits of this non-radioactive treatment for endometrial cancer," said Adam Dickler, MD, radiation oncologist at Little Company of Mary Hospital in Evergreen Park, Illinois. "The ability to deliver electronic X-ray based therapy directly to the tissue at risk, spares surrounding organs and gives us the ability to provide that therapy in a broader spectrum of clinical settings, making it safer and more accessible."

The performance of Electronic Brachytherapy to deliver non-radioactive therapy directly to cancer sites with minimal radiation exposure to surrounding healthy tissue, was the focus of five research studies recently presented at the 2008 World Congress of Brachytherapy hosted by the ABS. The studies bolster a growing body of research supporting use of Electronic Brachytherapy in the treatment of early stage breast cancer and gynecologic applications in which non isotope-based brachytherapy could be used to precisely deliver dose to targeted tissue.

In one study, "A Dosimetric Comparison of Xoft Axxent EB and Ir-192 HDR Brachytherapy in the Treatment of Endometrial Cancer," Dr. Dickler of Little Company of Mary Hospital compared treatment results using iridium-based brachytherapy and Electronic Brachytherapy. Results suggested equivalent target volume coverage for Electronic Brachytherapy while offering increased sparing of healthy bladder and rectum tissue by as much as 54 percent.

As a platform technology, the Axxent Electronic Brachytherapy System is designed to address a variety of oncological and non-oncological indications. Del
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SOURCE Xoft, Inc.
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