Navigation Links
FDA Approves GlaxoSmithKline's AVODART(R) in Combination with Tamsulosin for the Treatment of Symptomatic Enlarged Prostate
Date:6/19/2008

PHILADELPHIA, June 19 /PRNewswire-FirstCall/ -- GlaxoSmithKline (NYSE: GSK) today announced that the U.S. Food and Drug Administration (FDA) has approved AVODART (dutasteride) in combination with tamsulosin for the treatment of symptomatic enlarged prostate, a disease that affects half of all men over 50 years old. The new indication reflects emerging research showing the combination of the two medicines treats the symptoms of enlarged prostate more effectively than either medicine alone.

"The combination of AVODART and tamsulosin at diagnosis allows doctors to simultaneously treat the patient's prostate on two fronts by reducing prostate size and rapidly improving symptoms," said Steven A. Kaplan, M.D., from Weill Cornell Medical College of Cornell University in New York City.

Common symptoms of enlarged prostate include nocturia, frequent and urgent urination, incomplete emptying, starting and stopping, and weak stream. If left untreated, enlarged prostate can lead to hospitalization for the inability to urinate or prostate surgery.

AVODART already had been approved by the FDA for the treatment of enlarged prostate to improve urinary symptoms, reduce the risk of acute urinary retention (AUR), and reduce the risk of prostate-related surgery. Tamsulosin, an alpha-blocker, already had been indicated for the treatment of the signs and symptoms of enlarged prostate.

The FDA approval was based on two-year results of the CombAT (Combination of Avodart and Tamsulosin) study, one of the largest clinical trials to date of men with enlarged prostate. The CombAT study is the first long-term assessment of the combination of AVODART and an alpha-blocker. Study results were first presented in September 2007 at the 29th annual meeting of the Societe Internationale d'Urologie in Paris. The study was published in the February issue of the Journal of Urology.

The CombAT study results showed that combination therapy with AVODART and tamsulosi
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related biology technology :

1. Arpida Annual General Meeting of Shareholders Approves All Board Proposals
2. FDA Approves MIXJECT(TM), a Convenient, Easy-to-Use Drug Delivery System For Watson Pharmaceuticals TRELSTAR(R) DEPOT and TRELSTAR(R) LA
3. FDA Approves VYVANSE(TM) (lisdexamfetamine dimesylate), the First and Only Once-Daily Prodrug Stimulant to Treat ADHD in Adults
4. Maryland Approves Medicaid Reimbursement for ActiPatch(R)
5. Healthcare Coalition Approves Tools to Improve Patient Safety During Transitions of Care
6. Medicare Approves in Home Sleep Apnea Testing
7. 3SBio Inc. Approves Share Repurchase Program
8. Baxters Board of Directors Approves New Share Repurchase Authorization of $2 Billion
9. FDA Approves PRISTIQ(TM) for the Treatment of Adult Patients with Major Depressive Disorder
10. FDA Approves INTELENCE(TM) (etravirine) for HIV Combination Therapy
11. FDA Approves Additional Dosage Strengths of Shires ADHD Treatment VYVANSE(TM) (lisdexamfetamine dimesylate) Which May Help Physicians Tailor Treatment for Individual Patients

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2009)..., , AMSTERDA... the world,s,leading publisher of scientific, medi...ounced a major re-launch of Embase, its comprehens...n indexed records from more than 7,000,active, pee...ayed a key role in the advancement of new biomedic...
(Date:11/27/2009)..., , PARIS, November 27 /PRNewswire-Fi... approval to market Oralair(R) in both adults and ...ermany, the first country where,Oralair(R) has bee... Oralair(R) is now registered in Austria, Belg..., France, Germany, Greece, Hungary, Ireland, Italy...
(Date:11/25/2009)..., , BOSTON, Nov. 25 ...he H1N1 virus, genomic data from the 1918 pandemic... the current H1N1 pandemic, today issued its lates...shows that the lethality of the H1N1 ("Swine Flu")... during the virus,s current outbreak in the spring...
(Date:11/25/2009)..., , BEIJING, Nov. 25 /PRNewswi... developer and provider of vaccines, announced tod... to establish Sinovac (Dalian) Vaccine,Technology ...develop, produce,and commercialize human-use vacci...erience in developing and commercializing world-cl...
Breaking Biology Technology:Elsevier is Re-Launching "Embase" to be a Powerful Resource Providing Deep Insights and Answers to Biomedical Researchers 2Elsevier is Re-Launching "Embase" to be a Powerful Resource Providing Deep Insights and Answers to Biomedical Researchers 3STALLERGENES is Granted a Marketing Authorization for Oralair(R) in Europe 2STALLERGENES is Granted a Marketing Authorization for Oralair(R) in Europe 3Biological H1N1 Vaccines: Too Little, Too Late 2Biological H1N1 Vaccines: Too Little, Too Late 3Biological H1N1 Vaccines: Too Little, Too Late 4Biological H1N1 Vaccines: Too Little, Too Late 5Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities 2Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities 3
...merly Drug Royalty,Corporation Inc.) announced tod...d has launched a Structured Finance Fund with appr...ity fund is focused on providing,both revenue prod...ice,companies financing for a variety of uses. The...ital and a consortium of existing and new,investor...
...rporated,(Nasdaq: VICL ) today announced that Vij...will participate in a panel discussion on biodefen... 26th Annual JPMorgan Healthcare,Conference (San F...hosted by JP Morgan and McKenna, Long & Aldridge L...a, M.D., Former Special,Assistant to the President...
...atories, L.C., a,privately-owned biotechnology com...M.A.C.P., has joined the Company as Vice President...eeffe served as Professor of Medicine, Chief of,He...rogram at Stanford,University Medical Center. He i...ical Association and the American Society for,Gast...
Other Biology Technology:DRI Capital Launches Structured Finance Fund 2Vical to Participate in Pandemic Influenza Panel at JPMorgan Healthcare Conference 2Romark Laboratories Names Emmet B. Keeffe, M.D. Vice President and Chief Medical Officer 2
(Date:11/26/2009)... using recordings of birdsong to accurately measur...time sound recordings from a microphone array have...pecies, populations. Because the new technique, re...l of Applied Ecology , will also work with whale s...ty to monitor whale and dolphin numbers. , Devel...
(Date:11/26/2009)...head researchers have developed a new type of gene...nes and proteins used by pathogens, according to t...ltures genes are present in two copies: one inheri...inactivation by mutation is therefore inefficient ...opy usually remains active and takes over. , In ...
(Date:11/26/2009)... Aureus ) and other drug-resistant bacteria could ...ype devices have been developed to offer safe, qui... Two prototype devices have been developed: one fo...ds and feet) in hospitals and public spaces where ...shoot bacteria-killing agents into infested chroni...
Breaking Biology News(10 mins):Ecologists sound out new solution for monitoring cryptic species 2Knockouts in human cells point to pathogenic targets 2Plasma produces KO cocktail for MRSA 2Plasma produces KO cocktail for MRSA 3NuAire Laboratory Economic Stimulus Package Free Accessories or Factory Options 13569 1Wine May Shield Breast Cancer Patients From Radiation Side Effects 54558 1Wine May Shield Breast Cancer Patients From Radiation Side Effects 54558 2Violence at Town Hall Meetings Could Escalate 54553 1Violence at Town Hall Meetings Could Escalate 54553 2Violence at Town Hall Meetings Could Escalate 54553 3
...ted company with the last remnants of their legs a...etic event may have crowned an eons-long shrinking...ed by Hans Thewissen, Ph.D., a professor of anatom...icine, has used developmental data from contempora...to try to pinpoint the genetic changes that could ...
...iew of sperm whales, behaviour during their long, ...d electronic "dtags". According to new research pu...l of Animal Ecology, sperm whales ?like bats ?use ... at depth. , Working in the Atlantic, the Gulf o...ds Hole Oceanographic Institution and the Universi...
...ami Rosenstiel School of Marine and Atmospheric Sc...discovered new deepwater reef sites in the Straits...gh May 30, the Rosenstiel School scientists will w...olleagues to explore these areas for the first tim...ch,s Johnson-Se-Link II submersible, will search f...
Other Biology News:How ancient whales lost their legs, got sleek and conquered the oceans 2How ancient whales lost their legs, got sleek and conquered the oceans 3Ecologists home in on how sperm whales find their prey 2Deep-water discovery 2Deep-water discovery 3
BD FACSArray bioanalyzer from BD Biosciences - Immunocytometry Systems
...capability allows detection of SYBR Green I or FAM... in the second channel including TET, HEX, VIC, a...RT-qPCR and allelic discrimination. DNA Engine the... temperature gradient feature permits simultaneous...
SlideHyb Glass Array Hybridization Buffer #2 from Ambion
Fingerprinting II Informatix Dimensioning Techniques from Bio-Rad
Biology Products: