Navigation Links
Expert Neurology Panel Weighs Impact of New Reports of PML in Multiple Sclerosis Patients on Tysabri
Date:8/20/2008

SCOTTSDALE, Ariz., Aug. 20 /PRNewswire/ -- MedPredict, a global provider of pharmaceutical competitive intelligence and market research, has published a new report providing critical strategic insight for pharma and biotech companies with a stake in the market for multiple sclerosis (MS) therapies.

Biogen/Elan's Tysabri has been under scrutiny due to two additional reported cases of PML, a rare and potentially fatal brain disease associated with use of the drug. MedPredict recently convened an expert panel of neurologists to assess the significance of the PML cases, and the effect on prescribing and development of new potent immunosurveillants.

"Nobody at the Thought Leader level was surprised that there were more new (PML) events," according to Jeff Berk, MedPredict's president. "At the time of the reinstatement of the US license for Tysabri, the FDA Advisory Committee stated that they expected there to be more events. Our panel discusses whether that sentiment will translate to community-based neurologists."

The report also updates progress on other approaches to treatment of MS, including:

-- New interferons, integrin inhibitors, B-cell inhibitors, S1Ps, fumarates, neuroprotection/neuroregeneration.

-- The potential for vaccine or MAb approaches for the treatment or prevention of multiple sclerosis.

-- Which therapeutics in development to provide symptomatic benefits in MS are the most likely winners.

MedPredict's analysis also provides guidance for clinical trial design in MS. "There have been a number of high-profile failed trials, both in relapsing-remitting and in progressive MS," said Dr. Berk. "The panel talks about strategies for improving the odds of success through better designs and better metrics."

Companies and partnerships discussed in this report include: Acorda, Amgen/Epix, Artielle ImmunoTherapeutics, Avanir, BaroFold, Bayhill, Bayer-Schering, Bayer-Schering/Genzyme, Biogen, Biogen/Elan, Biogen/Genentech/Roche, Biogen/UCB, Daiichi Sankyo, Genentech, GSK, GSK/Genmab, GSK/Mitsubishi Tanabe, Lilly/BioMS, Merck, Merck-Serono, Novartis, Ono, Opexa, PDL/Biogen/Roche, Peptimmune, Roche/Actelion, Roche/Genentech, Sanofi-Aventis, Teva/Merck-Serono, Teva.

This report can be purchased by contacting MedPredict.

About MedPredict

MedPredict (http://www.medpredict.com) maintains a proprietary database of over 1,000 global physician thought leaders, including 40+ specialties in 30+ therapeutic categories. Based on primary interviews with these thought leaders, MedPredict publishes periodic reports in each category to keep clients up-to-date on emerging trends and competitive activity. The reports include thought leader reactions to recent publications and medical conferences, as well as clinical, regulatory and marketing activity.


'/>"/>
SOURCE MedPredict
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. Duff & Phelps Acquires Lumin Expert Group To Build Global Intellectual Property Practice
2. PerkinElmer Expertise and Solutions Integral to Food Safety Monitoring for the Beijing Games : Methods, Applications Expertise and Instrumentation Deployed in Mobile Laboratory
3. Leading AIDS Experts Urge Greater Focus on Behavior-Change Programs to Prevent HIV
4. Cepheid Introduces GeneXpert(R) Infinity-48 System at 2008 American Association of Clinical Chemistry Meeting
5. Informex365.com is Launched for Manufacturers in Search of Chemical Reactions Expertise
6. Pharmacy Students Taught Improved Medication Adherence and Holistic Health Services Through Program Incorporating InforMedixs Med-eXpert(TM) System
7. Online Career Tool Offers Live Expert Advice Component
8. Expert Consensus Panel Recommendation for Incorporating Lp-PLA2 Testing into Cardiovascular Disease Risk Assessment Guidelines
9. PAREXEL Experts to Address Key Industry Topics at the Drug Information Association 44th Annual Meeting
10. Experts From The Peer Group Provide Training on Dialogue-Based Influence at the SPBT Annual Conference
11. PAREXEL Product Development and Regulatory Experts to Attend the 2008 BIO International Convention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... 27, 2016 , ... Rolf K. Hoffmann, former senior vice ... University of North Carolina Kenan-Flagler Business School effective June 27. , ... with a focus on the school’s international efforts, leading classes and participating in ...
(Date:6/24/2016)... Epic Sciences unveiled a liquid biopsy ... PARP inhibitors by targeting homologous recombination deficiency (HRD) ... test has already been incorporated into numerous clinical ... Over 230 clinical trials are investigating ... PARP, ATM, ATR, DNA-PK and WEE-1. Drugs targeting ...
(Date:6/23/2016)... WI (PRWEB) , ... June 23, 2016 , ... ... supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, into ... for over 35 years, is proud to add Target to its list of ...
(Date:6/23/2016)... , June 23, 2016 Houston ... with the Cy-Fair Sports Association to serve as ... the agreement, Houston Methodist Willowbrook will provide sponsorship ... and connectivity with association coaches, volunteers, athletes and ... with the Cy-Fair Sports Association and to bring ...
Breaking Biology Technology:
(Date:5/24/2016)... Ampronix facilitates superior patient care by providing unparalleled technology to leaders of the medical ... premium product recently added to the range of products distributed by Ampronix. ... ... ... Ampronix News ...
(Date:5/12/2016)... May 12, 2016 WearablesResearch.com , a ... the overview results from the Q1 wave of its ... wave was consumers, receptivity to a program where they ... a health insurance company. "We were surprised ... says Michael LaColla , CEO of Troubadour Research, ...
(Date:4/28/2016)... , April 28, 2016 Infosys ... (NYSE: INFY ), and Samsung SDS, a global ... that will provide end customers with a more secure, fast ...      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... but it also plays a fundamental part in enabling and ...
Breaking Biology News(10 mins):