Navigation Links
Exosome Diagnostics and DxS Diagnostic Innovations Collaborate to Develop Blood-Based Tests for Key Cancer Mutations
Date:6/22/2009

NEW YORK, June 22 /PRNewswire/ -- Exosome Diagnostics, Inc. ("ExosomeDX") and DxS Ltd. ("DxS") today announced that they will collaborate on the development of blood-based companion diagnostics for key cancer gene mutations, such as KRAS, BRAF and EGFR. The collaboration will use DxS' industry leading Scorpions(R) real-time PCR Mutation Test Kits in conjunction with ExosomeDX's xOS(TM) technology which harvests high-quality nucleic acids from blood exosomes.

The collaboration will initially focus on developing blood-based measurement of KRAS, BRAF, EGFR and other key mutations for predicting patient response to targeted therapies. Blood-based mutation measurement is particularly valuable in circumstances where tissue bioavailability is limited such as in lung, pancreatic and ovarian cancers.

Exosomes are small microvesicles precipitously shed by all solid tumors into blood. They contain virtually the entire cancer tumor transcriptome. In studies, ExosomeDX has identified most mRNA and miRNA in circulating tumor derived exosomes, all protected in the exosome lipid bi-layer from any blood-based RNase. Initial findings were published in the December 2008 issue of Nature Cell Biology.

"There are over 180 companies investigating over 370 different molecular targeted cancer therapies, many of which will require high-quality, molecular companion diagnostics," said James McCullough, Chief Executive Officer Exosome Diagnostics. "Teaming with the world leader in this space is a critical step in providing a solution for pharmaceutical companies, researchers and clinicians to measure the key mutations DxS Scorpion probes target directly from blood."

"Combining the ability to pull high-quality mutations from a simple blood draw with the unparalleled sensitivity and specificity of our Scorpion assays will provide our pharmaceutical and research customers with an ideal solution in personalize
'/>"/>

SOURCE Exosome Diagnostics, Inc.; DxS Diagnostic Innovations
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Exosome Diagnostics Announces Additions to Management Team
2. Exosome Diagnostics Appoints Johan Skog, Ph.D., as Director of Genetics Research
3. Strategic Diagnostics to Present at Two Upcoming Investor Conferences
4. Strategic Diagnostics Updates Roth Conference Presentation Time
5. Alliance for Medical Devices, Instrumentation and Diagnostics formed between Fraunhofer Center for Manufacturing Innovation and Boston University
6. Rosetta Genomics to Present at the American Association of Cancer Research (AACR) "Molecular Diagnostics in Cancer Therapeutic Development" Conference
7. Indivumed Supports Roche Diagnostics With Immunohistochemistry Services and Clinical Specimens for Biomarker Discovery and Drug Development
8. Quest Diagnostics to Speak at the 2007 UBS Global Life Sciences Conference
9. BoVir(R) Named Best New Veterinary Diagnostics Product in International Animal Pharm Awards
10. Enigma Diagnostics Announces a European Commission Award of EUR3 Million to Fund the Development of a Point of Care Platform for the Rapid Diagnosis of Influenza Infections
11. MedAssets Supply Chain Systems Selects Siemens Medical Solutions Diagnostics for Chemistry, Automation and Immunoassay Solutions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2015)... , July 24, 2015 ... equities: PDL BioPharma Inc. (NASDAQ: PDLI ), Arena ... STEM ), Northwest Biotherapeutics Inc. (NASDAQ: NWBO ... Free research report on PDL BioPharma can be accessed ... the NASDAQ Composite ended at 5,146.41, down 0.49%, the ...
(Date:7/24/2015)... 24, 2015 Orexigen Therapeutics, Inc. (Nasdaq: ... the second quarter 2015 on Thursday, August 6 before ... a business update and discuss the financial results in ... Eastern Time (5:00 a.m. Pacific Time). The ... (800) 447-0521 (domestic) or (847) 413-3238 (international), participant code ...
(Date:7/24/2015)... 24, 2015 The global ... USD 27.8 billion by 2022, growing at an estimated ... a new study by Grand View Research, Inc. Development ... to result in significant reduction in cost of sequencing ... and usage rates of next generation sequencing throughout the ...
(Date:7/24/2015)... ... July 24, 2015 , ... ... any modern scientific or pharmaceutical laboratory. FreezerPro® is an intuitive, fast, reliable ... where a sample is located even before opening the freezer door! Popular ...
Breaking Biology Technology:Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 2Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 3Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 4Biotechnology Stocks in Motion -- PDL BioPharma, Arena Pharma, StemCells, Northwest Biotherapeutics, and Acorda Therapeutics 5Next Generation Sequencing (NGS) Market To Reach $27.8 Billion By 2022: Grand View Research, Inc. 2Next Generation Sequencing (NGS) Market To Reach $27.8 Billion By 2022: Grand View Research, Inc. 3Next Generation Sequencing (NGS) Market To Reach $27.8 Billion By 2022: Grand View Research, Inc. 4Next Generation Sequencing (NGS) Market To Reach $27.8 Billion By 2022: Grand View Research, Inc. 5RURO, Inc. Partners with Integrated Systems Engineering to Provide Comprehensive LIMS Software to Biobanks 2RURO, Inc. Partners with Integrated Systems Engineering to Provide Comprehensive LIMS Software to Biobanks 3RURO, Inc. Partners with Integrated Systems Engineering to Provide Comprehensive LIMS Software to Biobanks 4
... THE WOODLANDS, Texas, June 17 ... an Orphan Product Development Grant by the FDA,to support ... Pediatric Ventricular Assist Device (VAD). Dr. Christopher Almond of,the ... of,Clinical Affairs for Berlin Heart Inc. will serve as ...
... for liquid culture tests will accelerate access to improved ... BD (Becton, Dickinson and Company; NYSE: BDX ... (Foundation for Innovative New Diagnostics), a Swiss foundation that ... tools for poverty-related diseases, today announced a significant price ...
... OSLO, Norway, June 17 , ... to Improve Remission Rates and,Reduce Short-Term Mortality Compared to ... ASA (OSE: CLAVIS) today announces positive final results,from a ... elacytarabine,(CP-4055), in patients with late-stage acute myeloid leukaemia (AML). ...
Cached Biology Technology:Berlin Heart Inc. Receives FDA Orphan Product Development Grant 2BD and FIND Achieve Milestone in Global Battle Against MDR-TB 2BD and FIND Achieve Milestone in Global Battle Against MDR-TB 3BD and FIND Achieve Milestone in Global Battle Against MDR-TB 4Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia 2Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia 3Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia 4Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia 5Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia 6Phase II Trial Demonstrates Elacytarabine May Increase Survival Threefold in Patients With Late-Stage Leukaemia 7
(Date:7/23/2015)... , July 23, 2015 Research and ... of the "Global Outlook of the Biometrics ... The global biometrics market is ... and commercial applications owing to the uptake of ... a transformation that enhances the growth of biometrics ...
(Date:7/20/2015)... July 20, 2015  Acuity Market Intelligence,s latest ... Convergence of Commerce and Privacy" forecasts that between ... apps will be downloaded to smart mobile devices ... biometrics market is projected to generate more than ... the seven-year forecast period.    "Biometrics ...
(Date:7/9/2015)... 07, 2015 Research ... of the "Biometrics for Banking; Market & ... report to their offering. The adoption ... this growth and the forecast is that by ... for companies involved in delivering biometric systems to ...
Breaking Biology News(10 mins):Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3Biometrics on Smart Mobile Devices to Redefine Digital Identity with 12.9 Billion Biometric App Downloads between 2014 and 2020 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3
... studies could lead to a radical re-thinking about how ... "Six of the adult females that we followed ... far out on the Arctic sea ice," said Universit ... Professor Gilles Gauthier as part of an International Polar ...
... Michigan State University chemist could eventually lead to a ... are key to treating a number of diseases, including ... manufacture and research often are made within genetically modified ... tends to collect into what scientists call inclusion bodies. ...
... the Faculty of Life Sciences (LIFE) at the University of ... than milk chocolate, lessening our craving for sweet, salty and ... an efficient way to keep your weight down over Christmas. ... it is healthier to eat dark chocolate, but now scientists ...
Cached Biology News:Snowy owl -- a marine species? 2The dark chocolate version of Father Christmas is most filling 2
... • Enzyme concentration - 5 units/µL ... in higher yields ,• Leaves an 'A' ... DNA polymerase which exhibits very high activity ... applications. To ensure the quality of the ...
Our original highly-purified, robust Taq Polymerase which delivers consistently high yields and minimal background...
... DNA Polymerase is the most thoroughly characterized ... testimony to its overall utility and efficacy. ... ideal for PCR applications. , It ... ,, AmpliTaq DNA Polymerase is a ...
... DNA Polymerase is a versatile and easy-to ... PCR applications. GCpro Taq DNA Polymerase is ... E. coli, containing the DNA polymerase I ... a highly processive 5'-3' DNA polymerase activity. ...
Biology Products: