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Exelixis and GlaxoSmithKline Agree to Successfully Conclude Six-Year Discovery and Development Collaboration
Date:6/27/2008

s' compounds to demonstrate safety and efficacy in clinical testing; Exelixis' ability to conduct and complete a phase 3 clinical trial for XL184 at the referenced time; Exelixis' ability to conduct clinical trials sufficient to achieve positive completion; Exelixis' ability to successfully advance and develop additional compounds; the therapeutic and commercial value of Exelixis' compounds; and Exelixis' ability to enter into new collaborations, continue existing collaborations and receive milestones and royalties under Exelixis' collaborative agreements. These and other risk factors are discussed under "Risk Factors" and elsewhere in Exelixis' quarterly report on Form 10-Q for the quarter ended March 28, 2008, and other filings with the Securities and Exchange Commission. Exelixis expressly disclaims any duty, obligation or undertaking to release publicly any updates or revisions to any forward- looking statements contained herein to reflect any change in Exelixis' expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.

Exelixis and the Exelixis logo are registered U.S. trademarks.


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