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Exelixis Announces Senior Management Promotions
Date:1/4/2008

-Pamela A. Simonton Promoted to Executive Vice President and General

Counsel- -Gisela M. Schwab Promoted to Executive Vice President and Chief Medical

Officer-

SOUTH SAN FRANCISCO, Calif., Jan. 4 /PRNewswire-FirstCall/ -- Exelixis, Inc. (Nasdaq: EXEL) today announced promotions for two members of its senior management team. Pamela A. Simonton, Senior Vice President of Patents and Licensing, has been promoted to Executive Vice President and General Counsel and Dr. Gisela M. Schwab, Senior Vice President and Chief Medical Officer, has been promoted to Executive Vice President and Chief Medical Officer.

"I am happy to promote both Pamela and Gisela. Both have played key roles in Exelixis' accomplishments, and both promotions are well-deserved. Pamela will now have responsibility for all corporate legal matters and legal services in support of Exelixis' business and corporate objectives," said George Scangos, Ph.D., President and Chief Executive Officer of Exelixis. "Pamela has been responsible for all of the patent and licensing activity since her arrival in 2000 and has played a major role in our partnering activities as well. Dr. Schwab will continue to lead the Development Organization as we plan to move 3 compounds into pivotal trials in the first half of 2008."

Ms. Simonton has served as Senior Vice President, Patents and Licensing, since January 2004. Previously, she served as Vice President of Corporate Technology Development from April 2000 through December 2003. From July 1996 to April 2000, she served as Vice President, Licensing and Acquisitions for Bayer Corporation's Pharmaceutical Division. From September 1994 to July 1996, Ms. Simont
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SOURCE Exelixis, Inc.
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