Navigation Links
Etanercept Challenges Cortisone as Treatment for Sciatica
Date:11/7/2013

Los Angeles, California (PRWEB) November 07, 2013

A new randomized clinical trial (RCT) published in the November 1, 2013 issue of the journal Spine (1) provides new evidence for the efficacy of etanercept used off-label for relief of persistent sciatica associated with lumbar disc herniation, a common health problem with significant unmet medical need. Etanercept belongs to the class of potent anti-inflammatory drugs known as TNF inhibitors.

The new etanercept study follows a 2012 comparative effectiveness trial of epidural etanercept versus an epidural steroid injection that found etanercept to be superior to the epidural steroid(cortisone) injection(2).

The new Spine study joins three previous RCTs as the fourth RCT supporting the efficacy of etanercept for treating disc-related pain(1-4). The clinical evidence of the effectiveness of etanercept for this indication has been accumulating for more than a decade(1-9). Increasing basic science and clinical evidence supports the scientific rationale of TNF inhibition for neuroinflammation(10-19).

The first account of the favorable clinical effect of etanercept for sciatica, and the invention of epidural administration of etanercept for this indication, was published in 2001, authored by Edward Tobinick, M.D., the founder of the Institute of Neurological Recovery(INR)(20). Dr. Tobinick and his colleagues have written multiple peer-reviewed articles documenting the clinical effects of perispinal etanercept used at the INR off-label for sciatica, cervical radiculopathy, intractable low back pain and related symptoms associated with lumbar disc herniation(5-9, 21). Perispinal administration of etanercept is a patented invention of Dr. Tobinick(21). Please note that results can vary, not all patients respond, etanercept may have
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Enbrel® (etanercept) Patent Issued
2. Coherus maakt bekend dat CHS-0214 (Proposed Etanercept Biosimilar) het primaire eindpunt in belangrijk farmacokinetisch klinisch onderzoek heeft bereikt
3. Foundation of UMDNJ Receives Grand Challenges Tuberculosis Biomarkers Grant
4. Phigenics Research Challenges Accuracy Of Conventional Legionella Testing Protocol
5. QIAGEN Joins Grand Challenges in Global Health Initiative to Bring Advanced Point-of-Care Diagnostics to Worlds Poorest Countries
6. Functional Circulation LLC Receives Grand Challenges Explorations Grant for Groundbreaking Research in Global Health and Development
7. Biodetection 2012 Conference Brings Together Leading Organizations from Around the World to Address Challenges & Technology Advances in Detection and Identification of Biological Threats in Washington, DC from June 28-29, 2012
8. Healthcare Cloud Computing (Clinical, EMR, SaaS, Private, Public, Hybrid) Market - Global Trends, Challenges, Opportunities & Forecasts (2012 - 2017)
9. Conference Challenges Left-brain, Right-brain Dichotomy
10. Global water sustainability flows through natural and human challenges
11. Bayer Bee Care Center Helps Solve Bee Health’s Toughest Challenges
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... (PRWEB) September 30, 2014 ... solutions for drug discovery and related life ... consortium has chosen Genedata Selector as its ... (NGS) data. FUNGITECT is a European consortium ... fungal diseases via individualized anti-fungal drug therapies. ...
(Date:9/30/2014)... , Sept. 30, 2014  KemPharm, Inc., ... discovery and development of proprietary new molecular entity ... Patent and Trademark Office (USPTO) issued U.S. Patent ... entitled, "Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl ... Making and Use Thereof." The patent, ...
(Date:9/30/2014)... MAR, Calif. , Sept. 30, 2014 ... for women,s health announces its receipt of a patent ... FemmyCycle menstrual cup has also received FDA clearance in ... Canada, and the CE in Europe. This patent is related ... conjunction with this issuance, the company is releasing FemmyCycle ...
(Date:9/30/2014)... The overall research objective was to ... and use. Most researchers outsource NGS technologies; however, ... within the next 12 months. Data accuracy and ... sequencing instruments. Disease-related research is the dominant use ... to surge, with half of the respondents planning ...
Breaking Biology Technology:FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 2FUNGITECT Consortium Adopts Genedata Selector as Data Analysis Platform for Anti-fungal R 3KemPharm, Inc. Receives Patent from the USPTO for Novel Prodrug of Hydromorphone, KP511 2The FemmyCycle 2Global Next-generation Sequencing Trends 2
... GeneGo, Inc., the leading,systems biology tools company, announced ... Center of Excellence. MD Anderson researchers will have,institution-wide ... advanced support. MD Anderson specializes in cancer treatment ... clinical trials programs.,MetaCore will be used throughout many ...
... and VANCOUVER, Sept. 2 /PRNewswire-FirstCall/ - OncoGenex,Pharmaceuticals, ... the "Company") has,announced today that it has ... rights to develop and commercialize TOCOSOL(R),Paclitaxel. Under ... entitled to,receive royalty payments from future TOCOSOL ...
... EDISON, N.J., Sept. 1 PSKW, LLC, a ... the pharmaceutical,industry, announced today that it has significantly ... last year in the Supreme Court of the ... McKesson Specialty Arizona Inc.,("McKesson"), a wholly-owned subsidiary of ...
Cached Biology Technology:MD Anderson Becomes a GeneGo Center of Excellence Using MetaCore for Oncology Research 2OncoGenex Pharmaceuticals announces out-license of TOCOSOL Paclitaxel to Eagle Pharmaceuticals 2OncoGenex Pharmaceuticals announces out-license of TOCOSOL Paclitaxel to Eagle Pharmaceuticals 3PSKW Expands Its Lawsuit Against McKesson to Seek Assignment of McKesson's Patent Application 2
(Date:9/30/2014)... a suite of perilous threats in today,s ocean. ... climate change, fragile coral ecosystems are disappearing at ... some species of corals surrounding the island of ... in their tropical environment: coral guard-crabs. New research ... Marine Station scientist Seabird McKeon and the museum,s ...
(Date:9/29/2014)... species of gut bacteria called Clostridium ramosum , coupled ... The work is published this week in mBio , ... , A research team from the German Institute of ... gut bacteria including C. ramosum gained weight when ... C. ramosum were less obese even when consuming a ...
(Date:9/29/2014)... 1970 and 2010 populations of mammals, birds, reptiles, ... percent, says the 2014 Living Planet Report released ... loss occurs disproportionately in low-income countriesand correlates with ... In addition to the precipitous decline in wildlife ... signs about the overall health of the planet. ...
Breaking Biology News(10 mins):Smithsonian scientists discover coral's best defender against an army of sea stars 2Gut bacteria promote obesity in mice 2Half of global wildlife lost, says new WWF report 2
... chemotherapy for the treatment of skin cancer is one ... researchers successfully synthesized a natural substance that shows exceptional ... U of A chemistry professor Dennis Hall said after ... produced the substance called Palmerolide A. "The potency ...
... DigitalPersona, Inc., a leader in fingerprint identity ... a leading supplier of point-of-sale (POS) software for ... NextGen POS and Classic POS solutions. WAND,s quick-service ... cashier accountability and deter unauthorized manager overrides. ...
... the blink of a geologic eye global temperatures were ... come by. Today, the largest island in the world is covered ... hot spot for climate scientists. Why? Because tiny bubbles ... about global warming: how fast and how much will ice ...
Cached Biology News:WAND Point-of-Sale Solutions Integrate U.are.U(R) Fingerprint Biometrics From DigitalPersona for Quick-Service Restaurants 2WAND Point-of-Sale Solutions Integrate U.are.U(R) Fingerprint Biometrics From DigitalPersona for Quick-Service Restaurants 3As Greenland melts 2
...
N,N'-Methylene-bis-acrylamide, Ultra Pure...
... Serum; U.S. sourced, ideal for ... quality; Low hemoglobin; Endotoxin: < ... of US origin; U.S. sourced, ... an uncompromising quality. Low hemoglobin ...
NEWBORN CALF SERUM AND PLASMA...
Biology Products: