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Epizyme, Inc. Reports Second Quarter 2013 Financial Results
Date:7/31/2013

ith genetically defined cancers. Epizyme has built a proprietary product platform that the company uses to create small molecule inhibitors of a 96-member class of enzymes known as histone methyltransferases, or HMTs. HMTs are part of the system of gene regulation, referred to as epigenetics, that controls gene expression. Genetic alterations can result in changes to the activity of HMTs, making them oncogenic (cancer-causing). By focusing on the genetic drivers of cancers, Epizyme's targeted science seeks to match the right medicines with the right patients for a personalized approach to cancer treatment.

For more information, visit www.epizyme.com and connect with us on Twitter at @EpizymeRx.EPIZYME, INC. CONSOLIDATED BALANCE SHEET DATA (UNAUDITED)(Amounts in thousands)June 30,December 31,20132012Cash and cash equivalents

$
48,689$
97,981Total assets

162,044103,511Deferred revenue

56,93769,445Redeemable convertible preferred stock (Series A, B and C)

-76,156Stockholders' equity (deficit):

96,127(51,126) EPIZYME, INC.CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)(Amounts in thousands except per share data)Three Months Ended June 30,Six Months Ended June 30,2013201220132012Collaboration revenue

$
4,839$
5,342$
23,721$
20,996Operating expenses:Research and development

13,9378,89927,29818,127General and administrative

3,0791,6386,0773,545Total operating expenses

17,01610,53733,37521,672(Loss) income from operations

(2,177)4,805(9,654)(676)Other (expense) income, net

(35)51(55)64Net (loss) income

$
(2,212)$
4,856$
(9,709)$
(612)Less: accretion of redeemable convertible preferred stockto redemption value

107156264167Less: income allocable to participating securities

-4,354--(Loss) income allocable to common stockhold
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SOURCE Epizyme, Inc.
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