Navigation Links
EpiVax, Inc. forms Collaborative Research Agreement with Roche to Develop Tregitope Technology
Date:12/1/2009

a>, animal health and chronic infectious disease.

About Tregitopes
Tregitope is a set of regulatory T-cell epitopes found in the Fc region of IgG that induce the activity of the body’s own natural regulatory T cells. When administered in conjunction with other antigens or protein immunogens, the response to these immunogens is diminished and altered if the antigen/immunogens are co-administered with Tregitopes. Preliminary in vitro and in vivo studies indicate that the modification of the immune response is due to the induction of natural T reg cells.

Examples of potentially immunogenic protein therapeutics include erythropoietin and alpha interferon, as well as antibodies that have immunosuppressive and anti-inflammatory properties such as humira and rituximab. Like vaccines, protein therapeutics can engender both cellular and humoral immune responses. Anti-drug antibodies (ADA) may neutralize the therapeutic effects of the drug and/or alter its pharmacokinetics. Since the impact of immunogenicity can be quite severe, regulatory agencies are developing new guidelines for monitoring immunogenicity and drug developers are seeking to reduce immune responses through other means such as by inducing tolerance. The Tregitope technology induces the human body’s natural tolerance mechanisms, reducing the immunogenicity of co-administered proteins. The initial discovery was published in 2008, in the journal Blood, by EpiVax CEO and CIO De Groot and Martin.

About EpiVax
EpiVax, Inc. is dedicated to merging in silico, in vitro and in vivo immunology research to generate new therapeutics as well as new vaccines for infectious diseases. T cell epitope mapping, the selection of target peptides from any protein sequence, is a powerful resource for the development of novel protein therapeutics. EpiVax rese
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Page: 1 2 3

Related biology technology :

1. DSM Pharmaceutical Products Forms Manufacturing Alliance With Galenix
2. WaferGen Names Christopher Sears, Ph.D., Architect of High-Value Molecular Diagnostics and Computational Biology Platforms, to Companys Scientific Advisory Board
3. Bio-Organic Catalyst, Inc. Forms Joint Venture With SIF ICAP Mexico S.A. de C.V. as Exclusive Distribution Hub for Central America, Mexico and Caribbean.
4. MAQUET Cardiovascular Announces Leading Robotic Heart Surgeon Performs First Beating Heart Fully Endoscopic Bypass Surgery Using Miniaturized Cardiopulmonary Bypass System
5. Boston Scientifics Urology/Gynecology Business Forms Marketing Alliance with Bladder Health Network
6. Santaris Pharma A/S Forms Strategic Alliance With Shire plc to Develop RNA-Based Medicines for the Treatment of Rare Genetic Disorders
7. Laser technology creates new forms of metal and enhances aircraft performance
8. Surgeon Performs First Single Incision Peri-Umbilical Laparoscopic Surgery in the State of Missouri
9. Penguin Computing Forms OEM Agreement with Applied Biosystems for Scyld ClusterWare
10. Aesthera Announces ANVISA Clearance to Market Photopneumatic Platforms in Brazil
11. DATATRAK International, Inc. Forms Strategic Partnership with Inclinix, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
EpiVax, Inc. forms Collaborative Research Agreement with Roche to Develop Tregitope Technology
(Date:11/22/2014)... MA (PRWEB) November 21, 2014 ... key investors will gather on December 3rd at ... Biotech Conferences series. GeneticRx will take place at ... Medical School and will discuss the present and ... therapy, exon skipping, and gene editing—as well as ...
(Date:11/22/2014)... November 21, 2014 RURO, Inc., ... provider, has released Limfinity® version 5.1.4. , RURO’s ... of Limfinity® than ever in RURO’s 8 year ... minority framework enhancement. Limfinity® version 5.1.4 is the ... and beyond bug fixes! , Limfinity® 5.1.4 release ...
(Date:11/22/2014)... 2014 The “Chiral Chromatography Columns ... Material (Metal, Glass, Plastic), by Application [GC, LC ... Forecast to 2018” analyses and studies the major ... America, Europe, Asia, and Rest of the World. ... figures spread through 135 pages and in-depth TOC ...
(Date:11/22/2014)... 2014  The element of surprise has been a ... strike without warning. Until now, epidemiologists had nothing to ... outbreak, resulting in suboptimal responses to both the H1N1 ... Photo - http://photos.prnewswire.com/prnh/20141121/160242 ... because virus gene structural changes have been found that ...
Breaking Biology Technology:Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2RURO Announces Limfinity® version 5.1.4 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5Viruses' Advantage of Surprise is Lost 2
... Quanterix Corporation, a company enabling a new generation of ... ngle Mo lecule A rray (SiMoA ™ ... of its Prostate Specific Antigen (PSA) test, a fifth-generation ... predictor of five-year biochemical recurrence (BCR)-free survival following radical ...
... to make a highly efficient and yet cheaper silicon ... the cost of solar energy can be halved. ... Institute of Microelectronics (IME), the new thin-film silicon solar ... grade silicon. However it is able to generate electricity ...
... deCODE genetics today ... with Pfizer Inc., the objective of which is to ... to Systemic Lupus Erythematosis by utilizing deCODE,s expertise in ... extensive population and genetic resources, including DNA samples and ...
Cached Biology Technology:Quanterix PSA Test Found to be a Reliable Predictor of Prostate Cancer Recurrence Following Surgery 2Quanterix PSA Test Found to be a Reliable Predictor of Prostate Cancer Recurrence Following Surgery 3NTU and A*STAR Institute of Microelectronics develop cheaper yet efficient thin film solar cells 2deCODE Announces Agreement With Pfizer to Search for Variants in the Human Genome That Confer Risk of Systemic Lupus Erythematosis 2
(Date:11/10/2014)... U.S. store shelves in early 2010, and people have ... packets can be tossed into a washing machine without ... The convenience, though, has come with risks for young ... Children,s Hospital found that from 2012 through 2013, U.S. ... than 6 years of age swallowing, inhaling, or otherwise ...
(Date:11/7/2014)... CORAL SPRINGS, Florida , November 6, 2014 ... improved secure authentication for better mobile security revolutionizing online transactions. ... NXTD ), Alibaba Holdings Ltd. (NYSE: BABA ), ... MSFT ), eBay Inc. (NASDAQ: EBAY ... (NASDAQ: NXTD and NXTDW), a biometric authentication ...
(Date:11/6/2014)... is an asset for a predator. Except when that predator ... tiger beetle, relative to its size, is the fastest creature ... body lengths per second (at about five miles per hour). ... take the sprinting gold from the tiger beetle, a person ... The tiger beetle has a problem. At peak speeds, everything ...
Breaking Biology News(10 mins):Study finds laundry detergent pods, serious poisoning risk for children 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6The tiger beetle: Too fast to see 2
... in a virtual reality forest, will anyone hear an environmental message? ... cut down the make-believe redwood. New findings from Stanford researchers ... and told to saw through a towering sequoia until it crashed ... world than people who only imagined what it,s like to cut ...
... ST. LOUIS Saint Louis University researchers have identified ... fluid from tissues to lymphatic vessels. It may be possible ... organ to another organ and improve the effectiveness of vaccines. ... consisting of vessels in the body. It defends the body ...
... research by scientists at The Scripps Research Institute and collaborating ... that may provide a target for obesity and diabetes drugs. ... Cell Metabolism , the scientists describe a protein called ... signals that stimulate fat cell formation and turn off those ...
Cached Biology News:Stanford's virtual reality lab focuses on conservation 2Stanford's virtual reality lab focuses on conservation 3Outsmarting cancer cells: SLU scientists learn how they spread 2Scripps Research scientists find 'dual switch' regulates fat formation 2Scripps Research scientists find 'dual switch' regulates fat formation 3