Navigation Links
Enzyme promotes fat formation
Date:10/11/2007

The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in causing obesity.

The team found that TPPII actually stimulated the formation of fat cells in worms and mammalian cells and that by reducing it, fat stores decreased. Mice with lower levels of TPPII were thinner than their wild type littermates, although their food intake was comparable.

The authors hope that TPPII could be exploited as a drug target to help fight increasing levels of obesity; inhibiting the enzyme would both increase feelings of fullness after eating and decrease build up of fat cells.

Around 40 million Americans are obese and the UK Government predicts that 12 million adults in the UK will be obese by 2010 if nothing is done. Obesity is responsible for 70% of cardiovascular diseases and 80% of type II diabetes and represents a serious health risk and financial drain.


'/>"/>

Contact: Jonathan Graff
jon.graff@utsouthwestern.edu
214-648-1481
European Molecular Biology Organization
Source:Eurekalert

Page: 1

Related biology technology :

1. The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature
2. Comparing Fidelity and Performance of Proofreading PCR Enzymes
3. pfuturbo DNA Polymerase: A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning
4. Greater Amplification Specificity with New Hot Start PCR Enzyme
5. Enzyme Immunoassay for Studying Intracellular Levels of cAMP
6. Improve Amplification Specificity with Hot Start PCR Enzyme
7. Choice of RT-PCR Enzymes
8. Properties of PCR Enzymes
9. Select the Optimal Enzyme for RT-PCR
10. Enzyme Purification With the Econo-Pac Q Cartridge
11. Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3, 5 monophosphate and its validation for pharmacological screening at G protein-coupled receptors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2017)... , ... June 22, 2017 , ... The first human ... 20 years until the first data on cross-contamination of human cell lines with HeLa ... an increasing issue in cell culture labs and is associated with dramatic consequences for ...
(Date:6/20/2017)... (PRWEB) , ... June 20, 2017 , ... ... to immediately determine the adulterants which pose the most likely threat to their ... 28 of this year. , IFT's annual food expo attracts over 20,000 ...
(Date:6/19/2017)... , ... June 19, 2017 , ... ... all service activities supporting EDETEK’s products including training, implementation, support, and client process ... his new role. He has previously held leadership roles for service providers and ...
(Date:6/16/2017)... ... June 16, 2017 , ... Cambridge Semantics ... that its Anzo Smart Data Lake® (Anzo SDL) solution was named a ... 2017 Software & Information Industry Association (SIIA) CODiE Awards. , Finalists represent ...
Breaking Biology Technology:
(Date:4/11/2017)... 2017 Research and Markets has announced the ... to their offering. ... eye tracking market to grow at a CAGR of 30.37% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
(Date:4/11/2017)... 2017 NXT-ID, Inc. (NASDAQ:   NXTD ... the appointment of independent Directors Mr. Robin D. Richards ... of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief ... to their guidance and benefiting from their considerable expertise as ...
(Date:4/5/2017)... -- The Allen Institute for Cell Science today announces the ... and dynamic digital window into the human cell. The ... of deep learning to create predictive models of cell ... growing suite of powerful tools. The Allen Cell Explorer ... available resources created and shared by the Allen Institute ...
Breaking Biology News(10 mins):