Navigation Links
Enzyme promotes fat formation
Date:10/11/2007

The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in causing obesity.

The team found that TPPII actually stimulated the formation of fat cells in worms and mammalian cells and that by reducing it, fat stores decreased. Mice with lower levels of TPPII were thinner than their wild type littermates, although their food intake was comparable.

The authors hope that TPPII could be exploited as a drug target to help fight increasing levels of obesity; inhibiting the enzyme would both increase feelings of fullness after eating and decrease build up of fat cells.

Around 40 million Americans are obese and the UK Government predicts that 12 million adults in the UK will be obese by 2010 if nothing is done. Obesity is responsible for 70% of cardiovascular diseases and 80% of type II diabetes and represents a serious health risk and financial drain.


'/>"/>

Contact: Jonathan Graff
jon.graff@utsouthwestern.edu
214-648-1481
European Molecular Biology Organization
Source:Eurekalert

Page: 1

Related biology technology :

1. The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature
2. Comparing Fidelity and Performance of Proofreading PCR Enzymes
3. pfuturbo DNA Polymerase: A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning
4. Greater Amplification Specificity with New Hot Start PCR Enzyme
5. Enzyme Immunoassay for Studying Intracellular Levels of cAMP
6. Improve Amplification Specificity with Hot Start PCR Enzyme
7. Choice of RT-PCR Enzymes
8. Properties of PCR Enzymes
9. Select the Optimal Enzyme for RT-PCR
10. Enzyme Purification With the Econo-Pac Q Cartridge
11. Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3, 5 monophosphate and its validation for pharmacological screening at G protein-coupled receptors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... -- According to a new market research report "Top 10 ... Development, Flow Cytometry, Single-Use Bioprocessing, Biologics Safety Testing, Tangential Flow Filtration, Virus ... market is expected to reach USD 71.03 Billion by 2021 from USD ... 2021. Continue Reading ... ...
(Date:1/24/2017)... Pa. , Jan. 24, 2017   Bracket ... provider, today announced the addition of Jennifer Peters ... Senior Vice President and General Manager for the Scientific ... responsible for Bracket,s work in Rater Training, Quality Assurance, ... Bracket with a strong skillset and demonstrated record building ...
(Date:1/24/2017)... , Jan. 24, 2017  Asterias Biotherapeutics, ... the field of regenerative medicine, today announced positive ... 1/2a clinical trial that showed additional motor function ... 10 million AST-OPC1 cells in AIS-A patients with ... "Recovery of upper extremity motor function is critically ...
(Date:1/24/2017)... (PRWEB) , ... January 24, 2017 , ... ... instrument solutions, announces the appointment of Steven F. McAllister as Executive Vice President ... experience in both the U.S. and international markets. Beginning his career at Howmedica, ...
Breaking Biology Technology:
(Date:1/18/2017)... MINNETONKA, Minn. , Jan. 18, 2017 /PRNewswire/ ... eClinical technology company that supports the entire spectrum ... 2016 has been another record-breaking year for the ... and market interest in MedNet,s eClinical products and ... to the tremendous marketplace success of ...
(Date:1/12/2017)... PUNE, India , January 12, 2017 A new ... - 2022," projects that the global biometric technology market is expected to generate revenue ... 2022. Continue Reading ... ...      (Logo: http://photos.prnewswire.com/prnh/20140911/647229) ...
(Date:1/6/2017)... 2017  SomaLogic announced today that it has ... by iCarbonX, the China -based ... Digital Health Ecosystem that can define each person,s ... biological, behavioral and psychological data, the Internet and ... SomaLogic will provide proteomics data and applications expertise ...
Breaking Biology News(10 mins):