Navigation Links
Enzyme promotes fat formation
Date:10/11/2007

The enzyme TPPII may contribute to obesity by stimulating the formation of fat cells, suggests a study in EMBO reports this week. The enzyme, TPPII, has previously been linked to making people feel hungry, but Jonathan Graff and colleagues now show that it may be even more deeply involved in causing obesity.

The team found that TPPII actually stimulated the formation of fat cells in worms and mammalian cells and that by reducing it, fat stores decreased. Mice with lower levels of TPPII were thinner than their wild type littermates, although their food intake was comparable.

The authors hope that TPPII could be exploited as a drug target to help fight increasing levels of obesity; inhibiting the enzyme would both increase feelings of fullness after eating and decrease build up of fat cells.

Around 40 million Americans are obese and the UK Government predicts that 12 million adults in the UK will be obese by 2010 if nothing is done. Obesity is responsible for 70% of cardiovascular diseases and 80% of type II diabetes and represents a serious health risk and financial drain.


'/>"/>

Contact: Jonathan Graff
jon.graff@utsouthwestern.edu
214-648-1481
European Molecular Biology Organization
Source:Eurekalert

Page: 1

Related biology technology :

1. The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature
2. Comparing Fidelity and Performance of Proofreading PCR Enzymes
3. pfuturbo DNA Polymerase: A High-Performance, High-Fidelity Enzyme Ideal for PCR Cloning
4. Greater Amplification Specificity with New Hot Start PCR Enzyme
5. Enzyme Immunoassay for Studying Intracellular Levels of cAMP
6. Improve Amplification Specificity with Hot Start PCR Enzyme
7. Choice of RT-PCR Enzymes
8. Properties of PCR Enzymes
9. Select the Optimal Enzyme for RT-PCR
10. Enzyme Purification With the Econo-Pac Q Cartridge
11. Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3, 5 monophosphate and its validation for pharmacological screening at G protein-coupled receptors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... (PRWEB) January 15, 2014 2013 was ... Scottsdale’s Brain State Technologies®. They saw continued independent research ... Center who were awarded a $1 million grant from ... in “Brain and Behavior” a peer reviewed journal, Amy ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... AUSTIN, Texas , Jan. 14, 2014 ... analyze and research medicinal plants and therapeutic derivatives ... industry, health professionals, and researchers about the challenges ... (Logo: http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The ...
(Date:1/14/2014)... 2014 Global Record Systems, LLC, ... technology solutions for patients, physicians, the biopharmaceutical industry, ... today the signing of a three-year Research Collaboration ... Administration (FDA). This initiative is designed to ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... retains ownership of Pain Management business, NATICK, ... BSX ) today announced that it has completed ... business and drug pump,development program to former principals ... Bionics in 2004. The sale,coincides with the closing ...
... International,Associates, Inc., administrator for the HealthShares(TM) Indexes, a ... Funds,today announced that effective at the opening of ... MAXY ) will replace Aspreva Pharmaceutical,Inc. (Nasdaq: ... Inc. (NYSE: ALO ) will also replace ...
... with modest growth in the,traditional life science ... in agricultural, biodefense and molecular diagnostics. To,help ... and,advisory firm BioInformatics, LLC today released its ... of scientists working in,these dynamic markets. The ...
Cached Biology Technology:Boston Scientific Completes Sale of Auditory Business and Drug Pump Development Program 2Boston Scientific Completes Sale of Auditory Business and Drug Pump Development Program 3QED International Associates Announces Changes to the HealthShares(TM) Autoimmune-Inflammation and Neuroscience Indexes 2Study Examines Media Preferences of Life Scientists in Applied Markets 2Study Examines Media Preferences of Life Scientists in Applied Markets 3
(Date:4/24/2014)... It,s broadly understood that the world,s oceans play ... exchange of carbon between Earth,s ecosystems and atmosphere. ... UC San Diego have taken a leap forward ... , When phytoplankton use carbon dioxide to make ... material is released into the sea as a ...
(Date:4/24/2014)... COLUMBIA, Mo. When bacteria attack plants, they ... cells to weaken and suppress natural defenses. However, ... the plant cells as a potential host. Now, ... and replicated the process that allows the bacteriaknown ... discovery could lead to natural anti-infective treatments that ...
(Date:4/24/2014)... April 24, 2014GEN Publishing recently introduced ... focusing on the application of OMICs technologies in ... sequencing, are beginning to transform medical care just ... the past decade-and-a-half. , "GEN,s editors and reporters ... genomics, metabolomics, transcriptomics, etc. etc. for years," said ...
Breaking Biology News(10 mins):Microscopic organism plays a big role in ocean carbon cycling, Scripps scientists discover 2Microscopic organism plays a big role in ocean carbon cycling, Scripps scientists discover 3Plants send out signals attracting harmful bacteria, MU study finds 2
... at Rice University bolster the case for costly and ... in small populations of endangered species. , Worldwide, zoos ... thousands of miles in order to breed them with ... need for such programs, which can stress rare animals, ...
... challenges , Chemists have discovered details about how the tadpole-shaped ... into the top-most surface of water, an insight expected ... environmental hazards. The findings of a team led by ... on the cover of the Sept. 8 issue of the ...
... at the University of Pennsylvania have demonstrated that morphine ... enhancing virus replication. The paper by Wang et al., ... appears in the November issue of The American Journal ... , Hepatitis C virus (HCV) is common among ...
Cached Biology News:Costly breeding programs for endangered species pay off 2Costly breeding programs for endangered species pay off 3Scientists discover new way to look at how molecules twist and turn on water 2Hepatitis C complicated by morphine withdrawal 2
Application: for RNase- decontamination , Registered Trademark of Ambion. ,Special grade: for molecular biology Density: 1.00 g/mL (20 C) Suitab tst: RNase decontamination in accordance...
With L-glutamine and potassium bicarbonate. Sterile, Insect cell culture tested...
... meet the needs of the ... medium supports fast cell growth ... while maintaining high cell viability ... using the Baculovirus Expression Vector ...
Mol wt: average mol wt12,360.96 Da by calculation...
Biology Products: