Navigation Links
EntreMed Presents Interim Results for Phase 2 Carcinoid Tumor Study
Date:1/28/2008

Combination of Panzem(R) NCD and Avastin(R) May Slow Tumor Growth

ROCKVILLE, Md., Jan. 28 /PRNewswire-FirstCall/ -- EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, today announced the presentation of interim results for its Phase 2 multi-center study combining Panzem(R) NCD with Avastin(R) (bevacizumab) in patients with advanced or metastatic carcinoid tumors. The data were presented by principal investigator, Matthew Kulke, M.D., from the Dana-Farber Cancer Institute, during the 2008 Gastrointestinal Cancers Symposium being held in Orlando, Florida.

(Logo: http://www.newscom.com/cgi-bin/prnh/20010620/ENMDLOGO )

Thirty-one patients received oral Panzem(R) NCD daily in combination with Avastin(R) administered intravenously every other week. Of the 29 evaluable patients, 27 patients (87%) had stable disease and 2 patients (7%) had progressive disease as their best response. Fourteen of the 31 patients have been treated for at least six months, and 9 of the 14 have been treated for over one year. Results demonstrate that the combination of Panzem(R) NCD and Avastin(R) is well tolerated in advanced carcinoid tumor patients. The current analysis includes median follow up time over 8 months. Median progression-free survival and overall survival have not yet been reached. Enrollment in the trial is closed and 9 patients remain on study.

Carolyn F. Sidor, M.D., M.B.A., EntreMed's Vice President and Chief Medical Officer, commented on the results, "This study was designed to evaluate the combination of two antiangiogenic agents, Panzem(R)
'/>"/>

SOURCE EntreMed, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related biology technology :

1. EntreMed Announces FDA Acceptance of IND Application for Aurora Kinase/Angiogenesis Inhibitor, ENMD-2076
2. EntreMed Appoints Senior Vice President of Research and Development
3. EntreMed to Present at ThinkEquity Partners 5th Annual Growth Conference
4. ThromboGenics Presents Results of the Phase I Trial of TB-402 at the Prestigious American Society of Hematology Annual Meeting
5. ThromboGenics Presents Results of the Vitreomacular Traction Trial (MIVI IIT) at the American Society of Retina Specialists Annual Meeting
6. BAI Retail Delivery Conference Softpro Presents Next Generation Signature Tablet
7. Arpida Presents Data on Iclaprim at Scientific Congress in Germany
8. Resverlogix Presents Key Apo-Al/HDL Scientific Data at DALM
9. Arpida Presents Preclinical Data on AR-2474 at ICAAC
10. Arpida Presents Preclinical and Clinical Data on Iclaprim at ICAAC
11. Sangamo BioSciences Presents Data Demonstrating In Vivo Protection Against HIV Infection by CCR5-ZFN Therapeutic

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)..., REDWOODCITY,Calif.,Nov.24/PRNewswire-FirstC...cedthatRandyScott,GenomicHealth,sExecutiveChairman...onferenceinNewYorkCityonTuesday,December1,2009at10...hivedwebcastofthepresentation,visittheInvestorRela...stor.genomichealth.com .Pleaseconnecttothewebsitea...
(Date:11/24/2009)... Chemical Abstracts Servic..., reports that China,s patent office is now the wo...tions in chemistry. China trailed Japan,s patent o...n (WIPO), and the United States Patent and Tradema...ed the USPTO in 2005, WIPO in 2006, and exceeded J...
(Date:11/23/2009)... CHAMPAIGN, Ill. You can think of it as origami ...ersity of Illinois have developed a technique for ...silicon structures from thin films by coupling pho... capillary interactions. , The films, only a few ...s not possible with thicker pieces of the same mat...
(Date:11/23/2009)..., INCLINEVILLAGE,Nev.,Nov.23/PRNewswire-First...nnouncedthatNASDAQhasestablishedNovember27,2009ast...ostockholdersresultingfromthesecuritizationtransac...donDecember15,2009toallstockholdersofrecordonthere...pershareamountofthedividendat$1.67pershareofcommon...
Breaking Biology Technology:Genomic Health to Present at Piper Jaffray Health Care Conference 2China Leads All Nations in Publication of Chemical Patents According to CAS, the World's Most Authoritative Publisher of Chemical Information 2China Leads All Nations in Publication of Chemical Patents According to CAS, the World's Most Authoritative Publisher of Chemical Information 3Water droplets direct self-assembly process in thin-film materials 2PDL BioPharma Announces Ex-Dividend Date of November 27 for Special Dividend 2
...nder where their future technologists will come fr...ol students soon will graduate from an intensive i...ough the University of Wisconsin-Madison,s Inform...re-college program that provides hands-on training... color and economically disadvantaged students att...
...ntrepreneurial activity has remained consistent ov... in gender, demographic, geographic and ethnic mak...entrepreneur, according to a national assessment o...uffman Foundation . , ,The Kauffman Index of Entre... Midwest, which had the lowest level of entreprene...
...mation has reached an agreement to acquire Indust...rial controls company, for $218 million. , ,Headqu...siness as ICS Triplex , a global supplier of crit...tries. , ,Keith Nosbusch, chairman and chief exec...es an important strategic fit for Rockwell,s proce...
Other Biology Technology:Kauffman study shows consistent entrepreneurial growth 2
(Date:11/25/2009)...e officers and ambulance workers faced a terrifyin... They battled to save people from the collapsing T...and evacuated as many people as they could in an a...d making their jobs even harder was the problem of... relatives jammed mobile networks with calls and t...
(Date:11/25/2009)...professors recently received funding from the Nati... beneficial to understanding the environment. The ...wood, assistant professor in the Department of Bio...o separate research projects. , His first projec...s and Functions from the Leaf to the Landscape," w...
(Date:11/24/2009)...to understanding how sounds associated with Navy s...or if they hear it at all. , The same type of la... to detect flaws in the space shuttle,s behemoth s...ek inside the giant head of a whale. The scans are...a whale,s hearing anatomy using a breakthrough met...
Breaking Biology News(10 mins):Magic box for mission impossible 2Magic box for mission impossible 3Kent State University professors focus research on the environment with grants totaling $890,000 2Rocket science leads to new whale discovery 2Ex NFL Players Hold Their Own Health Wise 59259 1Ex NFL Players Hold Their Own Health Wise 59259 2Locate a Male Menopause Physician with reNEW MAN 59257 1Locate a Male Menopause Physician with reNEW MAN 59257 2Locate a Male Menopause Physician with reNEW MAN 59257 3Locate a Male Menopause Physician with reNEW MAN 59257 4Discrete Reportable Transcription to Populate the EHR EMR With Physician Dictated Reports 59255 1Discrete Reportable Transcription to Populate the EHR EMR With Physician Dictated Reports 59255 2Discrete Reportable Transcription to Populate the EHR EMR With Physician Dictated Reports 59255 3
...ASHINGTON -- A new NASA-led study shows human-caus...ge of Earth,s natural systems, including permafros...and lakes declining in productivity in Africa. , ...r Space Science in New York and scientists at 10 o...cal impacts since 1970 with rises in temperatures ...
...ore than 1,400 of the world,s top experts on evolu...or "Evolution 2008," the world,s largest annual ga..., the premier international event for scientists t...d by the University of Minnesota,s Bell Museum of ...gical Sciences and Minnesota Citizens for Science ...
...This release is available in Spanish . , A sci...), Georgia (USA), Hawaii (USA) and Nakai (China), ...ruit genomic sequence, in this case papaya (Carica... of the prestigious journal Nature . One of the r... Molecular Genetics of the Department of Genetics...
Other Biology News:NASA study links Earth impacts to human-caused climate change 2University of Minnesota to host world's largest conference on evolution 2Scientists decipher fruit tree genome for the first time 2Scientists decipher fruit tree genome for the first time 3
...reparation contains a unique β-agarose digest...titative recovery of intact DNA and RNA from low m...horesis in TAE, TBE, MOPS, or phosphate buffers. T...OPS, and phosphate electrophoresis buffers or GELa...
...e (TdT) is an intracellular marker normally presen...subpopulation of bone marrow prelymphocytes. Eleva...TdT cells are found to be associated with some lym...dT thus provides a useful adjunct in the different...
Ovine IFN Tau from PBL InterferonSource
...in the forefront of chemical peptide synthesis - b...olution. , Our Functional Peptides are controlle...xtra cost, thus we can provide products that meet ...xpert peptide scientists will support you starting...
Biology Products: