Navigation Links
Enabling Technologies Consortium (ETC) Issues Request for Information Regarding Technologies for the Enhancement of Process Understanding during Drying in Agitated Dryers
Date:3/7/2017

The Enabling Technologies Consortium™ (ETC), a consortium of pharmaceutical and biotechnology companies dedicated to collaboratively developing improved chemistry, manufacturing and control technologies for the pharmaceutical industry, is seeking information from companies on possible improvements to current drying technologies.

The drying unit operation is used extensively in the pharmaceutical industry and is a critical step in the synthesis of a drug product. Limitations in current technology constrain the development of an optimum drying protocol in the drug development process. The current state of real time data collection over the course of the drying process suffers from limitations of existing PAT tools, process measurements, and material sampling technologies. Current PAT tools cannot collect data at multiple points and suffer from equipment constraints that make it difficult to obtain a holistic picture of the heterogeneity in the drying process. Additionally, existing methodologies for scale-up or process transfer between different dryer types often result in issues with agglomeration or attrition and consequently batch failure. The current design of many dryers also does not allow for the collection of representative samples during the drying process without interrupting the process, making it difficult to discern how the powder quality attributes evolved over the course of the process.

Ultimately, the concern with the limitations in the current capabilities for real time data collection during drying is the inability to collect meaningful data for the development of closed loop control systems, model validation/verification or to pursue the design of effective scale-down equipment.

To address this need, ETC is seeking to work with companies interested in supplying equipment that can be used for PAT, process characterization, or sampling. PAT equipment should be capable of real time measurement of solvent composition, form, and particle size distribution; process measurement equipment should measure work and shear; and dryer equipment should enable automated sampling during drying in agitated dryers without breaking vacuum to allow for off-line testing. The goal of this collaborative project is joint development of instrument prototype(s) which could be used at lab and/or commercial scale and address one or more aspects in drying technology advancement. The hope is the prototype(s) will become commercial product(s) in the future.

As a first step in establishing this partnership, ETC has placed an open call to the vendor community by means of a “Request for Information” (RFI) through the ETC website, http://www.etconsortium.org. The purposes of this RFI are to: (1) solicit information and interest from the vendor community in collaborating on this project and (2) allow vendors to learn more about the technology requirements sought by ETC members. This RFI provides collective hardware and software requirements and performance criteria collected from a cross-pharmaceutical group of drying technology users. The information collected during the RFI process will be used by ETC members as part of the selection process to identify a collaborator or collaborators to develop drying technologies.

We invite any vendor who may be interested in this project to participate by downloading the RFI from the ETC website and submitting a response by the April 3, 2017 deadline.

About Enabling Technologies Consortium™: (http://www.etconsortium.org)
The Enabling Technologies Consortium™ (ETC) is comprised of pharmaceutical and biotechnology companies collaborating on issues related to pharmaceutical chemistry, manufacturing, and control with the goal of identifying, evaluating, developing, and improving scientific tools and techniques that support the efficient development, and manufacturing of pharmaceuticals. The purpose of this consortium is to identify pro-actively high-value opportunities to deliver innovative technologies where the business case is compelling and collaboration with the broader external community is required. For more information please contact the Secretariat at info@etconsortium.org.

Read the full story at http://www.prweb.com/releases/etc/dryingrfi/prweb14123163.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related biology technology :

1. Digital Solutions Partnership Between Cisco & RoviSys; Enabling Informed Decisions Based on Reliable Manufacturing Data
2. Benchling Announces First Of Its Kind Molecular Biology 2.0 Software Enabling Scientists To Run Thousands Of Experiments At Once
3. Enabling Technologies and CallTower Partner to Provide Enhanced Enterprise Voice in the Cloud
4. Enabling Technologies Consortium (ETC) Issues Request for Information (RFI) Regarding Online Ultra-High Performance Liquid Chromatography and Probe-Based Sampling
5. Enabling Technologies Consortium (ETC) Issues Request for Information (RFI) Regarding Development of Medium Throughput Personal Reactor Platform
6. Norgen Biotek Corp. Announces Supply Agreement with Biodesix Enabling the First EML4-ALK Liquid Biopsy Test with Results in 72-Hours
7. Elsevier to Showcase Solutions for Empowering Knowledge, Enabling Action at HIMSS16
8. ‘Wonder of Nanotechnology’ Details Research Enabling Nanoscale Optoelectronic Devices
9. New Equipment Installed: Enabling Continuous Processing Services at GEA Pharma Systems
10. Glowing Plant Releases Maker Kit, Enabling Anyone to Make a Glowing Plant at Home
11. Life Technologies Launches New Bioinformatics Software Platform Enabling Bio-Design and Gene Synthesis from Next Generation Sequencing Data
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2019)... , ... March 05, 2019 , ... San Fransisko, or ... Deborah, purchased him at four years old to pursue a career in dressage. ... was the most talented horse that she’d ever worked with. Unfortunately, Sisko suffered ...
(Date:2/27/2019)... ... February 26, 2019 , ... Superior Controls, Inc., a leading ... 140 employees on both the east and west coasts, today announced that employee ... New Hampshire. Sandmaier, a senior project engineer, joins Taggart McCormick, P.E., Anthony Whitesell, ...
(Date:2/22/2019)... ... February 20, 2019 , ... Ocean Tomo ... Systems. , The patents in lot 92 relate to ... used to distinguish between human users and computers through exploiting the fundamental differences ...
(Date:2/12/2019)... ... February 12, 2019 , ... Innovaderm Research, Inc., an ... extend their use of Medrio, the leading provider of eClinical technology for early-phase ... a regular Medrio customer for over nine years, primarily using the software in ...
Breaking Biology Technology:
(Date:3/14/2019)... ... 2019 , ... Bode Technology (Bode), a leading provider of forensic DNA analysis products ... assault kits. As thousands of untested kits are identified across the country, Bode continues ... Bode has tested more than 50,000 kits in the last three years alone. ...
(Date:3/13/2019)... ... March 13, 2019 , ... Leak Detection Associates , the ... Medical Device Industries, is excited to announce that it will be returning to ... the newly installed and highly experienced management team immediately marked Interphex as ...
(Date:3/9/2019)... ... March 07, 2019 , ... AESKU.GROUP – a ... – is pleased to announce the launch of the AESQC.com web ... lot-specific information, including pattern images for AESQC quality controls. , In July this ...
Breaking Biology News(10 mins):