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Empire Genomics and Reprogenetics Join Forces to Improve Preimplantation Genetic Diagnosis (PGD)
Date:10/15/2007

- Data on Successful Use of New PGD Technique to be Presented at American

Society for Reproductive Medicine (ASRM) Annual Meeting - - Improved Techniques Could Lead to Improved Overall Pre-natal Screening for Spontaneous Pregnancies as well as PGD with In Vitro Fertilization -

BUFFALO, N.Y., and LIVINGSTON, N.J., Oct. 15 /PRNewswire/ -- Empire Genomics, developing high throughput technologies that enable genome-wide analyses, and Reprogenetics, a genetics laboratory specializing in Preimplantation Genetic Diagnosis (PGD), announce data supporting a new technique to significantly improve the identification of genetic and chromosomal abnormalities from just a single or small group of embryonic cell(s). The microarray-based technology from Empire Genomics, tested and developed for in vitro fertilization in partnership with Reprogenetics, has multiple advantages when applied to PGD:

-- The test has the ability to screen all chromosomes - conventional

techniques typically selectively screen approximately half.

-- The test can be performed during the standard timeline of IVF with a

one day turnaround time.

-- It can successfully be performed with the genetic material of a single

cell sample.

-- It works rapidly and efficiently for preimplantation use with in vitro

fertilization.

The data will be presented jointly by Empire Genomics and Reprogenetics at the 63rd Annual Meeting of the ASRM in Washington, D.C. on Wednesday, October 17, 2007.

"We are convinced this new technology will enable us to improve screening for genetic defects as well as improve the pregnancy outcome for patients undergoing IVF by reducing spontaneous abortions and genetically affected conceptions," said Santiago Munne, Ph.D., Reprogenetics director. "Currently PGD requires highly skilled and experienced embryologists to process the cells for the current technology. This new technology simplifies this ste
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SOURCE Reprogenetics
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