Navigation Links
Elusys Releases New Data On Anthrax Anti-Toxin Administered Via Intramuscular Injection From Three Recent Animal Studies
Date:7/31/2013

bed to anthrax while the group treated with 16 mg/kg at that time point showed 50% (3/6) survival. All animals treated with placebo at 18 hours post-challenge succumbed to anthrax.

The second study was a randomized, four-arm, placebo-controlled, post-challenge, timed-treatment study. Animals were treated with a single dose of ETI-204 (16 mg/kg IM) at 24, 36 or 48 hours after challenge with aerosolized B. anthracis spores. The primary endpoint was survival at 28 days after spore challenge. The group treated with ETI-204 (16 mg/kg IM) 24 hours post-challenge demonstrated a survival rate of 93% (13/14) which was statistically significantly higher than the 10% (1/10) survival rate seen in the control group. The groups treated with ETI-204 at 36 or 48 hours post-challenge demonstrated survival rates of 43% (6/14) and 29% (4/14), respectively. 

A planned secondary analysis revealed that 100% (15/15) of animals dosed with ETI-204 before becoming bacteremic (having evidence of bacteria in the blood stream) survived, and 30% (8/27) of animals dosed with ETI-204 after becoming bacteremic survived. These results were presented, in part, at the recent ASM Biodefense and Emerging Diseases Research Meeting, Washington, DC, February 2013.

A third study examined the pre-challenge protection duration of ETI-204. The study was a randomized, blinded, four-arm, placebo-controlled study in animals dosed with ETI-204 prior to challenge with B. anthracis spores. Animals were administered a single dose of ETI-204 (16 mg/kg IM) at either 24, 48 or 72 hours prior to challenge with aerosolized B. anthracis spores. The primary endpoint was survival at 56 days after challenge. All animals receiving ETI-204 survived to 56 days post-challenge, regardless of the time ETI-204 was administered prior to challenge. Ninety percent (9/10) of animals dosed with placebo prior to challenge died within the first 14 days following
'/>"/>

SOURCE Elusys Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Elusys Awarded Additional $50.2 Million Under An Exisiting U.S. Government Contract To Support Final Stages Of Development Of ETI-204, For Treatment Of Inhalational Anthrax
2. HealthCare Institute of New Jersey Releases 2011 Biopharmaceutical and Medical Technology Economic Impact Data
3. HCCS Releases ICD-10 Countdown Clock With Integrated CMS Twitter Tweets
4. eCareSoft Releases eCS Cirrus™
5. AtheroNova Releases 2011 Financial Results
6. Atlanta LASIK Surgeon Dr. Ashraf Releases YouTube Videos Featuring Patient Testimonials and Discussion of Common Eye Treatments
7. ILVO-T&V Belgium Releases Validation Report of the Charm Sciences Beta-lactam and Tetracycline 2-minute Test for Raw Commingled Milk
8. ISPE Releases New Guidance for Designing and Constructing Packaging, Labeling and Warehousing Facilities
9. Happtique Releases Draft App Certification Program Standards For Public Comment
10. ClearCanvas Releases New Workstation Products Designed to Assist With Image Sharing
11. OneMedPlace Releases Update to Research Report on Amarantus Biosciences Focused on New Positive Ischemic Heart Disease Efficacy Data for MANF in Animals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... 22, 2014 The Board of Directors of BD ... declared a quarterly dividend of 54.5 cents per common share ... September 9, 2014. The indicated annual dividend rate is $2.18 ... is a leading medical technology company that partners with customers ... and evolving health needs. Our innovative solutions are focused on ...
(Date:7/22/2014)... within a phylum so full of mean little creatures, the ... its cruelty -- at least to crickets. Native to the ... most predatory sort of parasite. It swoops onto the back ... and leaves its wicked brood to invade, kill and consume ... would be possible without the fly,s ability to find a ...
(Date:7/22/2014)... Institute of Standards and Technology (NIST) and California ... design for an atomic clock that is based ... , The microcomb clock, featured on the cover ... Optica ,* is the first demonstration of ... conversion of optical frequencies to lower microwave frequencies. ...
(Date:7/22/2014)... in water with ultrasound and they,ll spin around their ... yet knows exactly. But researchers at the National Institute ... it,s fast. At up to 150,000 revolutions per minute, ... object submerged in liquid ever reported. , The discovery ... that they could be used not only for moving ...
Breaking Biology Technology:Fly-inspired sound detector 2Fly-inspired sound detector 3Fly-inspired sound detector 4'Comb on a chip' powers new NIST/Caltech atomic clock design 2NIST shows ultrasonically propelled nanorods spin dizzyingly fast 2
... Get Full-length cDNA , ... to improve production of full-length cDNA. This engineered reverse transcriptase, , ... href="http://www.ambion.com/catalog/CatNum.php?2048">ArrayScript , ... cDNA than wild type RTs, and rivals even ...
... Screening with small interfering RNAs , ... in biological pathways. This article analyzes ... of two strategies--transfection of individual , ... screening experiments. The increased effectiveness of testing , ...
... Isolate total RNA and protein from cultured cells or tissues , ... RNA and protein from cultured , cells , ... Ambion's new PARIS Kit uses a fast, simple procedure based ... native protein , from the same experimental sample. The kit ...
Cached Biology Technology:ArrayScript RT: Maximize Yields of Full-length cDNA 2ArrayScript RT: Maximize Yields of Full-length cDNA 3Are siRNA Pools Smart? 2Are siRNA Pools Smart? 3Are siRNA Pools Smart? 4Are siRNA Pools Smart? 5Are siRNA Pools Smart? 6Are siRNA Pools Smart? 7Are siRNA Pools Smart? 8Are siRNA Pools Smart? 9A Better Way to Isolate RNA AND Protein From the Same Sample 2A Better Way to Isolate RNA AND Protein From the Same Sample 3A Better Way to Isolate RNA AND Protein From the Same Sample 4A Better Way to Isolate RNA AND Protein From the Same Sample 5
(Date:7/22/2014)... July 14, 2014, by lightning from a weather system that ... four fires: Stokes Fire, Gold Hikes Fire, French Creek Fire ... are now one larger fire. The fires are burning in ... 243,000 acres in size. The present fire situation continues ... and firefighter safety is the priority on the Carlton Complex ...
(Date:7/22/2014)... MIAMI A new study that examined the survival ... as,unintentional bycatch in commercial longline fishing operations found ... with bigeye thresher, dusky, and scalloped hammerhead being ... the University of Miami (UM) Rosenstiel School of,Marine ... Ecosystem Science and Policy, provides,new information to consider ...
(Date:7/22/2014)... known as the ,1000 Bull Genomes Project, aims to ... cattle while also improving animal health and welfare. Results ... the whole genomes of 234 individual bulls whose direct ... reported in the journal Nature Genetics . , ... information to reduce or eliminate hereditary diseases and to ...
Breaking Biology News(10 mins):New study reveals vulnerability of sharks as collateral damage in commercial fishing 2Whole-genome sequencing of bulls in key beef and dairy breeds 2
... study comparing human walking and running motions and whether the ... these motions researchers at North Carolina State University show that ... the ankles generate more of the power when humans run. Knees ... The research could help inform ...
... Spain have used forensic mitochondrial DNA species identification techniques ... makes it possible to genetically differentiate between the fish, ... it easier to monitor the degree to which fisheries ... cell organelles is ideal for distinguishing between ...
... Beginning in June 2011, Springer will launch a ... Sciences ( HCIS ). As part of the ... Korea-based Future Technology Research Association International (FTRA). ... the official international journals of the FTRA. The journal ...
Cached Biology News:Hips take walking in stride; ankles put best foot forward in run 2Sardines and horse mackerel identified using forensic techniques 2Springer launches new open access journal with Korean research society 2
Borosilicate Glass. Certified for use with the Beacon 2000 Systems, 1,000 tubes/case...
... Engineered with new technology incorporating ... for unsurpassed flexibility, the new Varian ... advanced spectrometer available today., ,The Varian ... each transmitter and receiver channel, providing ...
Luminometers...
... Dr. P Set from different ... More organs maybe available upon ... two items from the whole set, ... set price. All Dr. P ...
Biology Products: