Navigation Links
Elevation of Brain Magnesium Reverses Memory Deficits in Alzheimer Mice
Date:5/16/2013

HAYWARD, Calif., May 16, 2013 /PRNewswire/ -- Scientists at the Center for Learning and Memory, Tsinghua University, Beijing, and the California-based biopharmaceutical company Magceutics, Inc. (www.magceutics.com) have demonstrated a novel therapy for reversing memory decline in mice with Alzheimer's Disease. By increasing brain magnesium levels, they find significant cognitive improvement in advanced stage AD mice. The study is the first to demonstrate a mechanism for reversing cognitive decline for advanced stage AD mice, and is also the first to show an effective long term treatment for early stage AD mice.

"We found that the elevation of brain magnesium can prevent cognitive decline in Alzheimer's Disease model mice," explained Magceutics founder Guosong Liu , a professor at Tsinghua University and senior investigator on the study. The report, which appeared online May 8th in the Journal of Neuroscience, shows that a newly developed magnesium compound known as Magtein™ (Magnesium-L Threonate) can prevent cognitive impairment when administered to mice with early stage AD. The treatment was shown to remain effective for at least 16 months. Additionally, Magtein significantly improved memory and cognition when given to advanced stage AD mice.

Liu and colleagues believe that because the loss of neuronal connections in brain regions critical for memory function is major hallmark of Alzheimer's Disease, preventing those losses can lead to new treatment options. In earlier studies, they determined the principle for controlling the density and plasticity of connections (synapses) between neurons in the hippocampus, the brain region that processes memory. Those studies revealed that the elevation of brain magnesium can selectively reduce background calcium within synapses and thereby enhance sy
'/>"/>

SOURCE Magceutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Flexible Sensors Offer Unprecedented View of Brain Activity During Epileptic Seizures
2. Implanted neurons, grown in the lab, take charge of brain circuitry
3. Study finds chronic abnormal brain blood flow in Gulf War veterans
4. QIAGEN Gains Rights to Genomic Biomarkers for Lung, Brain and Other Cancers to Expand its Pipeline of Companion Diagnostics
5. Scientists decode brain waves to eavesdrop on what we hear
6. Accelerate Brain Cancer Cure and Exosome Diagnostics Collaborate to Advance Clinical Studies of Exosome Biofluid Molecular Diagnostics Technology in Brain Cancer
7. Novel compound halts tumor spread, improves brain cancer treatment in animal studies
8. Brain-activated muscle stimulation restores monkeys hand movement after paralysis
9. How selective hearing works in the brain
10. New Stem Cell Found in the Brain
11. People with paralysis control robotic arms to reach and grasp using brain computer interface
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... England , January 15, 2014 A ... win races on the Formula 1 track could help to ... McLaren Applied Technologies (MAT), Stowhealth (a GP surgery based in ... by healthcare provider Simplyhealth. Telemetry technology, which is ...
(Date:1/15/2014)... NY (PRWEB) January 15, 2014 The Microcompetition ... a major disease. One of these latent viruses is the ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory ... theory, a study found that RA patients have high concentrations ...
(Date:1/15/2014)... CA (PRWEB) January 15, 2014 ... research solutions, today announced that Lupin Limited, one of ... Freeslate’s CM Protégé PharmD System for high ... Mumbai, India, is focused on a wide range of ...
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: ... 1360 Almshouse Road, Warrington, Pa. , Details: The ... to finding a cure for hepatitis B and improving the ... annual Crystal Ball on Friday, April 11 at Warrington Country ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... tickles your feet or the red Bordeaux smacking on your ... special chemical markers. These markers, called isotopes, can tell scientists ... they traveled, and what happened to them along the way. ... Stanford chemists have developed a new method to make isotopic ...
... PROMOTIONAL SYSTEMS, INC. (Pink Sheets: VGPR) today announced it has ... to assist the Company in building a biomass production facility ... its intention to build a biomass plant in Georgia to ... State,s Bioenergy Corridor. Georgia ranks third in the nation ...
... Inc. (Nasdaq: NVAX ) announced today its ... vaccine technology to ROVI Pharmaceuticals (Madrid: ROVI) of Spain. ... a comprehensive influenza vaccine solution for the Spanish government ... by the Spanish Ministry of Health and other government ...
Cached Biology Technology:Stanford researchers find a quicker, cheaper way to sort isotopes 2Stanford researchers find a quicker, cheaper way to sort isotopes 3Vega Picks Tennessee Firm to Assist with Construction of Biomass Plant in Georgia 2Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 2Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 3Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 4Spanish Government Selects Novavax's VLP Technology for Comprehensive Flu Vaccine Solution in Spain 5
(Date:4/17/2014)... Our eyes not ... with a continuous stream of information about our own movements. ... a car the world glides by us and leaves ... our brain calculates self-motion from this "optic flow". This way, ... during our own movements. Together with biologists from the University ...
(Date:4/17/2014)... hydrogen sulfide in order to properly multiply and form ... Center for Craniofacial Molecular Biology at the Herman Ostrow ... principal investigator on the project, said the presence of ... of calcium ions. The essential ions activate a chain ... creation of new bone tissue, and keeps the breakdown ...
(Date:4/17/2014)... Rajendra Singh Thursday as a "Champion of Change" ... deployment in the residential, commercial and industrial sectors. ... Electrical and Computer Engineering and director of Clemson,s ... hero leading the charge across the country to ... and driving policy changes at the local level ...
Breaking Biology News(10 mins):How vision makes sure that little fish do not get carried away 2How vision makes sure that little fish do not get carried away 3How vision makes sure that little fish do not get carried away 4White House honors Clemson professor as 'Champion of Change' for solar deployment 2
... not the most hospitable place on Earth, but at least ... The bacteria -- Chryseobacterium and Paenisporosarcina ... the laboratory that was designed to simulate as closely as ... of Arctic and Antarctic glaciers, said Corien Bakermans, assistant professor ...
... in which a key cell of the immune system prepares ... processes that take place within these cells and could lead ... cancer. The research focused on the neutrophil, the most ... the immune system, its job is to seek out and ...
... canines were on a mission to sniff out trouble ... of an Office of Naval Research (ONR)-hosted "Top Dog ... by helping them move through the battle space," said ... Program, part of ONR,s Expeditionary Warfare and Combating Terrorism ...
Cached Biology News:Hardy bacteria help make case for life in the extreme 2UCSF team uncovers how immune cells move against invaders 2Marine's best friend shows explosive-detecting capabilities 2
CircuLex Anti-Human S100P Polyclonal Antibody Research Focus: proliferation Storage: -20C Shipping Temperature: 4C...
...
Raised to arginine vasopressin coupled to bovine thyroglobulin with carbodiimide ....
Anti-LC3 Polyclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Biology Products: