The Phase 2b study, GOLDEN-1 (Glycopyrrolate for Obstructive Lung Disease via Electronic Nebulizer), is a randomized, double-blind, placebo-controlled, multi-center, seven arm, four-period cross-over, incomplete block, 7-day dosing study to assess the dose-response, safety, and efficacy of EP-101 in subjects with moderate to severe COPD.
The ERS annual meeting is taking place September 24-28 in the Amsterdam Convention Center in the Netherlands. Information regarding the ERS presentation is below and a full abstract is available through the ERS website at www.erscongress2011.org.
Poster Title: Efficacy and safety of nebulized glycopyrrolate (EP-101) for administration using high efficiency nebulizer in patients with COPD. D. Singh, B. Leaker, A. Tutuncu.
Abstract Number: P869, Session: 96, Sept 25, 12:50 – 14:40, Amsterdam Convention Center
COPD is a slow progressive disease comprising chronic bronchitis and emphysema caused largely by smoking. Despite anti-smoking campaigns, COPD is the fastest growing major disease in the U.S. and around the world. COPD is now the third leading cause of death in the U.S. and is expected to be the third leading cause in the world by 2020. The disease is largely managed with inhaled bronchodilators and corticosteroids to improve lung function and reduce the frequency of exacerbations. Longer-acting agents and combinations have proven successful for treating many COPD patients, but the sicker and older segment of the COPD population (15-20%) who require nebulizer therapy are limited to shorter-acting agents and long treatment times resulting in reduced compliance and outcomes.
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|SOURCE Elevation Pharmaceuticals, Inc.|
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