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Edwards Lifesciences Celebrates 50 Years of Life-Saving Innovations
Date:4/3/2008

me today and the more than 5,600 employees worldwide who carry on his mission to provide treatments and hope for patients with advanced cardiovascular disease."

"It brings me tremendous joy that the replacement heart valves Lowell Edwards and I co-developed 50 years ago began a company that today continues to pioneer live-saving cardiovascular devices and procedures," said Dr. Albert Starr, medical director of the Providence Heart and Vascular Institute and co-recipient of a 2007 Lasker Award for the development of artificial heart valves. "I'm proud of my enduring association with Edwards Lifesciences and look forward to the company's continued success helping millions of patients worldwide."

In 1958, Lowell Edwards was a 60-year-old recently retired engineer with 63 patents in an array of industries, an entrepreneurial spirit and dreams of helping patients with heart disease. With a background in hydraulics and fuel pump operations, he believed the human heart could be mechanized. He presented the concept to Dr. Starr, a young surgeon at the University of Oregon Medical School, who encouraged Lowell Edwards to focus first on developing an artificial heart valve, for which there was an immediate need. After only two years, the first Starr-Edwards mitral valve was designed, developed, tested and successfully placed in a patient.

About Edwards Lifesciences

Edwards Lifesciences is the global leader in the science of heart valves and hemodynamic monitoring. Headquartered in Irvine, Calif., Edwards treats advanced cardiovascular disease with its market-leading heart valve therapies, and critical care and vascular technologies. In 2008, Edwards celebrates 50 years of partnering with clinicians to develop life-saving innovations. The company's global brands, which are sold in approximately 100 countries, include CardioVations, Carpentier-Edwards, Cosgrove-Edwards, FloTrac, Fogarty, PERIMOUNT Magna and Swan-Ganz. Additional company information c
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5. Edwards Lifesciences to Host Earnings Conference Call on February 5, 2008
6. Edwards Lifesciences Receives FDA Approval to Add Transapical Delivery System to U.S. Clinical Trial of Transcatheter Heart Valve
7. Edwards Lifesciences Completes Acquisition of CardioVations Product Line
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9. Marshall Edwards, Inc. to Present at BIO Investor Forum 2007
10. Medarex to Present at the A.G. Edwards 2nd Annual Emerging Growth Conference
11. Edwards Lifesciences Grants UC Irvine $5 Million to Establish the Edwards Lifesciences Center for Advanced Cardiovascular Technology
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