Navigation Links
Ectopic eyes function without connection to brain
Date:2/27/2013

MEDFORD/SOMERVILLE, Mass. (February 27, 2013) For the first time, scientists have shown that transplanted eyes located far outside the head in a vertebrate animal model can confer vision without a direct neural connection to the brain.

Biologists at Tufts University School of Arts and Sciences used a frog model to shed new light literally on one of the major questions in regenerative medicine, bioengineering, and sensory augmentation research.

"One of the big challenges is to understand how the brain and body adapt to large changes in organization," says Douglas J. Blackiston, Ph.D., first author of the paper "Ectopic Eyes Outside the Head in Xenopus Tadpoles Provide Sensory Data For Light-Mediated Learning," in the February 27 issue of the Journal of Experimental Biology. "Here, our research reveals the brain's remarkable ability, or plasticity, to process visual data coming from misplaced eyes, even when they are located far from the head."

Blackiston is a post-doctoral associate in the laboratory of co-author Michael Levin, Ph.D., professor of biology and director of the Center for Regenerative and Developmental Biology at Tufts University.

Levin notes, "A primary goal in medicine is to one day be able to restore the function of damaged or missing sensory structures through the use of biological or artificial replacement components. There are many implications of this study, but the primary one from a medical standpoint is that we may not need to make specific connections to the brain when treating sensory disorders such as blindness."

In this experiment, the team surgically removed donor embryo eye primordia, marked with fluorescent proteins, and grafted them into the posterior region of recipient embryos. This induced the growth of ectopic eyes. The recipients' natural eyes were removed, leaving only the ectopic eyes.

Fluorescence microscopy revealed various innervation patterns but no
'/>"/>

Contact: Alex Reid
alexander.reid@tufts.edu
617-627-4173
Tufts University
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Theravalues Confirms Beneficial Effects of Theracurmin™ on Diastolic Function in Hypertensive Patients
2. Functionalized graphene oxide plays part in next-generation oil-well drilling fluids
3. Nanowiggles: Scientists discover graphene nanomaterials with tunable functionality in electronics
4. REVIVE Trial Results for Avanafil Published in JSM Demonstrate Significant Improvement in Erectile Function
5. Adeona Announces Initiation of Phase II Clinical Trial of Trimesta™ for Cognitive Dysfunction in Multiple Sclerosis
6. Functional oxide thin films create new field of oxide electronics
7. Interim Clinical Trial Results Confirm Safety of Renadyl™, a Probiotic Dietary Supplement for the Support of Healthy Kidney Function
8. Aged hematopoietic stem cells rejuvenated to be functionally younger
9. Functional Circulation LLC Receives Grand Challenges Explorations Grant for Groundbreaking Research in Global Health and Development
10. Seahorse Launches Reagent to Make Functional Fatty Acid Oxidation (FAO) Assays Easy
11. RURO Adds Critical Level Monitoring Functionality to its Inventory Management Software FreezerPro.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Ectopic eyes function without connection to brain
(Date:12/19/2014)... --  ISN has released its third annual U.S. ... publication series. With data aggregated from over eight billion ... its online contractor management platform, ISNetworld, this three-part series ... statistics. The Contractor Performance ... available in two industry specific volumes: Oil & ...
(Date:12/17/2014)... Bellingham, Washington, USA (PRWEB) December 16, 2014 ... Kirstin Baum, manager at Philipps- Universität Marburg’s Department ... optics and photonics, in the newly released ... 2015-2016. “And never be too shy to ask ... STEM (science, technology, engineering, and mathematics) occupations ranging ...
(Date:12/17/2014)... 2014 This report is a ... industry. For an overview analysis, the report introduces ... chain structure, industry overview, policy analysis, and news ... has witnessed rapid development with key manufacturers ... This report mentions quartz tubing upstream raw materials ...
(Date:12/17/2014)...  Vermillion, Inc. (NASDAQ: VRML ), a ... the next step in its expanded strategy to rebuild ... the naming of current Chief Operating Officer, Valerie ... current Chairman of the Board and CEO James ... changes are effective January 1, 2015. "Jim ...
Breaking Biology Technology:ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 32020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4
... June 2, 2011 Morphotek®, Inc., a subsidiary of ... multi-center, phase II study of MORAb-004 for the treatment ... potentially first-in-class monoclonal antibody that specifically binds to endosialin/tumor ... its safety and therapeutic activity at two dosages. ...
... Calif., June 2, 2011 Life Technologies Corporation ... performed in cooperation with the University Hospital Muenster, Germany, on ... bacterium at the root of the deadly outbreak in Germany ... strains. The data obtained from the DNA ...
... electrodes have been coated with a drug-loaded polymer in ... a number of neurological symptoms, such as those associated ... In a study published today, 2 June 2011, ... researchers have developed a novel technology to precisely modulate ...
Cached Biology Technology:Morphotek®, Inc. Announces Initiation of MORAb-004 Phase II Study in Melanoma 2Morphotek®, Inc. Announces Initiation of MORAb-004 Phase II Study in Melanoma 3DNA Sequencing Data Reveals New Hybrid E. coli Strain is Cause of German Outbreak 2DNA Sequencing Data Reveals New Hybrid E. coli Strain is Cause of German Outbreak 3DNA Sequencing Data Reveals New Hybrid E. coli Strain is Cause of German Outbreak 4New technology could inspire brain implant for detecting and treating seizures 2
(Date:12/19/2014)... 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ... its team and bring LaunchKey to market in 2015. ...
(Date:12/17/2014)... 16, 2014 Valencell, a leader in performance ... technology to industry leaders such as Intel, Jabra, Atlas, ... biometric wearable products. These products will be showcased at ... Las Vegas . "Our partners ... and robust – with the clinical data to back ...
(Date:12/11/2014)... 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition ... Region 2015-2019"  report to their offering. ... is advances in technology. With continuous advances in ... to the latest standard that meets the needs ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... , The bottled water, soda pop, or micro brew-beer that ... cities contains a natural chemical imprint related to geographic location. ... imprint in your hair that could be used to track ... believed to be the first concerted effort to describe the ...
... looking for new antibiotics: A new research published in the ... ( http://www.fasebj.org ) explains for the first time how honey ... protein that they add to the honey, called defensin-1, which ... infections and to develop new drugs that could combat antibiotic-resistant ...
... WEST LAFAYETTE, Ind. - Fast-food restaurants can supersize French ... to supersize a type of apple. Peter Hirst, a ... in some Gala apple trees causes some apples to grow ... reported in the current issue of the Journal of ...
Cached Biology News:Beverages leave 'geographic signatures' that can track people's movements 2Honey as an antibiotic: Scientists identify a secret ingredient in honey that kills bacteria 2Apples grow larger when cells don't divide, study shows 2
This antibody detects an ~25 kDa band, corresponding to the expected molecular mass of Rab3A, on immunoblots. The antibody specificity is confirmed in peptide inhibition immunoblotting studies....
... antibody reactive against the complex IV assembly factor ... growing cultured cells. SURF1 is an important assembly ... to participate in the folding of subunit II ... of SURF1, particularly ones that result in an ...
100 g monoclonal antibody which can immunocapture ~10 g of Complex IV from heart mitochondria. Also included are 2 mg of bovine heart mitochondria for control immunocapture....
Rabbit polyclonal to GPR56 ( Abpromise for all tested applications). entrezGeneID: 9289 SwissProtID: Q9Y653...
Biology Products: