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ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials
Date:5/21/2013

ferior in the first study), with the two groups being comparable at the end of the study.

(9) Floege, J et al. "EFFECT OF CINACALCET USE ON ALL-CAUSE MORTALITY: PARALLEL ANALYSES IN ARO INCIDENT OBSERVATIONAL EUROPEAN HEMODIALYSIS POPULATION AND IN EVOLVE TRIAL"

This analysis in a cohort of the prospective observational ARO study (the design of the EVOLVE study was "reconstructed" in this analysis) showed a treatment effect comparable to that in EVOLVE. The authors concluded that the results of the randomized EVOLVE study can be transposed to a broader population.

(10) Wang, A et al. "ORAL PARICALCITOL TREATMENT ON LEFT VENTRICULAR MASS AND FUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS WITH CARDIAC HYPERTROPHY (OPERA STUDY): A RANDOMIZED CONTROLLED TRIAL"

The study investigated the effect of oral paricalcitol on left-ventricular mass after 52 weeks of therapy. The result revealed no significant difference from placebo in terms of left-ventricular mass index and also of the other cardiac endpoints. However, during treatment there was a significant improvement in the biochemical parameters of CKD-MBD (PTH and alkaline phosphatase).

Background information and the study abstracts can be downloaded:

http://www.era-edta2013.org/en-US/press

Contact
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D-99423 Weimar
E-Mail: press@era-edta.org
Fon: +49-(0)36-43 / 77-64-23
Mobile: +49-(0)174 / 21-65-629


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SOURCE European Renal Association - European Dialysis and Transplant Association (ERA-EDTA)
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