Coordinated by the European Organisation for Research and Treatment of Cancer (EORTC) and run under the BIG/TRANSBIG networks, MINDACT aims to provide confirmatory evidence that patients with a low recurrence risk signature by Mammaprint® may be spared chemotherapy and its burdensome side effects, without negative repercussions on survival rate. MINDACT, which involved sites in the Netherlands, France, Germany, Belgium, Spain, Italy, UK, Slovenia, and Switzerland, began recruiting patients in 2007 and its first results are expected in approximately three years.
Ancillary research is led by TRANSBIG, a consortium launched by BIG (Breast International Group) in 2004 and supported by the European Union's 6th Framework Program to promote international collaboration in translational research. Further research grants have been received from the Breast Cancer Research Foundation, Novartis, F. Hoffman La Roche, Sanofi-Aventis, the National Cancer Institute (NCI), the EBCC-Breast Cancer Working Group, the Jacqueline Seroussi Memorial Foundation, Prix Mois du Cancer du Sein, Susan G. Komen for the Cure, Fondation Belge Contre le Cancer, Dutch Cancer Society (KWF), Association Le Cancer du Sein, Parlons-en!, Deutsche Krebshilfe and the Grant Simpson Trust and Cancer Research UK. Whole genome analysis is provided in kind by Agendia.
This trial would not have been possible without such support and the collaboration of hundreds of healthcare professionals across multiple disciplines, and above all without the trust and participation of all the patients.
For more information on MINDACT please visit:
|SOURCE Agendia B.V.|
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