Navigation Links
EORTC, BIG, and Agendia Announce Completion of Patient Recruitment for International MINDACT Study
Date:10/18/2011

BRUSSELS, IRVINE, California, and AMSTERDAM, October 18, 2011 /PRNewswire/ --

The EORTC, BIG, and Agendia, a commercial-stage molecular cancer diagnostics company, today announced the completion of patient registration for the EORTC 10041/BIG3-04 MINDACT (Microarray In Node negative and 1-3 positive lymph node Disease may Avoid Chemotherapy Trial) study. More than 6,600 patients in 111 institutions across nine countries were enrolled from February 2007 to July 2011 in this trial.

Genomic risk profiling lies at the heart of personalized management of cancer.  MINDACT is investigating the added clinical value of MammaprintTM to standard clinicopathological criteria for the accurate selection of breast cancer patients for adjuvant chemotherapy. The study aims to provide further evidence that early breast cancer patients with a low recurrence risk genomic profile by Mammaprint® may not need chemotherapy.  This would spare patients from burdensome side effects without increasing the risk of metastasis or reducing survival. The study is also designed to show whether MammaPrint® can predict patient response to specific therapies.

Commercialized by Agendia, MammaPrint® has been cleared by the FDA as a prognostic tool identifying patients at low risk of metastasis, and can already be used across the spectrum of breast cancer cases for this purpose (including ER positive and negative, and lymph node negative and positive). It is being tested in MINDACT to provide large-scale prospective validation of its clinical utility.

"The completion of patient recruitment is a major milestone for this groundbreaking trial. If MammaPrint® is ultimately shown to predict individual patient response to the trial specific cancer therapies currently on the market, it will likely create significant and valuable synergies for the manufacturers
'/>"/>

SOURCE Agendia B.V.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Agendia Successfully Completes Bi-Annual FDA Inspection
2. Agendia Presents Broad Array of Predictive and Prognostic Studies on Breast and Colorectal Cancers at ASCO 2010 Annual Meeting
3. Agendia Receives New York State Laboratory Permit and Laboratory Accreditation by College of American Pathologists
4. Medicare Administrator Establishes Reimbursement Coding Policy for Agendias Breast Cancer Recurrence Test MammaPrint(R)
5. Agendia Raises US $23 Million in Series E Financing
6. Agendia Supports Genentechs Citizens Petition Urging FDA to Hold In-Vitro Diagnostic Tests to One Set of Scientific and Regulatory Standards
7. Agendia Opens CLIA-Registered U.S. Genomics Laboratory
8. Agendia to Present Multiple Predictive and Prognostic Studies on Breast and Colorectal Cancers at ASCO Annual Meeting
9. Agendia to Present at BioCenturys Future Leaders in the Biotech Industry Conference
10. Agendia Presents Data Supporting MammaPrints Predictive and Prognostic Power at 2009 St. Gallen Breast Cancer Conference
11. Agendia Appoints Seasoned Diagnostics Executive Albert A. Luderer to Supervisory Board
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... Dec. 22, 2014  ( www.competitivehealth.com ) — Competitive ... medical bill review and advocacy service, has signed an ... WellCard Savings discount health services marketplace. 63% ... more than they expected to pay. As part of ... costs, WellCard Savings is pleased to offer medical bill ...
(Date:12/22/2014)... 22, 2014 Fertility Associates of Memphis ... Bank USA , a network of more than 20 ... partnership, patients have fast access to a national pool ... IVF . Fertility Associates of Memphis is the only ... treatment option. , Dr. William Kutteh , director ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one ... of Nick Maroulis, Pharm.D. to the newly created position ... In this position, Dr. Maroulis will continue to manage ... of our multi-site pharmacies as the company expands. Dr. ... that time he has served in many different capacities ...
(Date:12/19/2014)... Dec. 19, 2014 Bina Technologies, Inc. (Bina, ... that they have been acquired by Roche (SIX: RO, ... privately held company that provides a big data platform ... (NGS) data for the academic and translational research markets. ... and will continue to focus on development of their ...
Breaking Biology Technology:WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... ... to provide online tutorial suite, Quick Reference Cards, and other training and outreach programs. ... Seattle, WA (PRWEB) April 13, ... has partnered with OpenHelixTM to provide comprehensive training and outreach programs for its ...
... Researchers at Uppsala University have developed a new method ... Hopes are strong that the method represents an important ... new diagnostic tests. The new method, which ... should enable studies of the effects of genetic variation ...
... ... Deliver Results Faster with New User Interface and Improved Support for Complex Experiments. ... (PRWEB) April 12, ... life science research, today announced Genedata Screener® 8. Developed over the past year to ...
Cached Biology Technology:RCSB PDB Teams with OpenHelix to Announce Free Tutorial and Training Materials 2RCSB PDB Teams with OpenHelix to Announce Free Tutorial and Training Materials 3Mutations directly identifiable in active genes 2Genedata Screener 8 Advancing Analysis of HCS, HTS and Time Series Data Debuts at SBS 16th Annual Conference 2Genedata Screener 8 Advancing Analysis of HCS, HTS and Time Series Data Debuts at SBS 16th Annual Conference 3Genedata Screener 8 Advancing Analysis of HCS, HTS and Time Series Data Debuts at SBS 16th Annual Conference 4
(Date:12/24/2014)...  Since its launch in December 2014, the ... eliminate the pain of trying to remember their usernames ... own biometrics fused to their smartphones. To assist people ... Hoyos Labs , the company that created 1U and ... offering the app for free. 1U is ...
(Date:12/22/2014)... Conn. , Dec. 22, 2014  NXT-ID, Inc. ... the "Company"), a biometric authentication company focused on the ... pickpocket, entertainer and security consultant, Apollo Robbins ... biometric smart wallet.  Apollo Robbins ... and 7 th , 2015, demonstrating some of his ...
(Date:12/22/2014)... 2014 Research and Markets ... of the "The Global Watermarking and ... http://photos.prnewswire.com/prnh/20130307/600769 ... of the global digital media watermarking and ... monitor piracy by securely and invisibly embedding ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4The Global Watermarking and Fingerprinting Markets 2
... Calif. Each year, dengue fever infects as many as ... 30,000 deaths worldwide. Both diseases are spread by infected ... to produce eggs. The blood feeding and the egg development ... virus. Now a team of entomologists at the University ...
... a jetliner act and feel one way when crammed together ... different mindset when the middle seat is empty and they ... that exists among the proteins involved in health and disease ... of Chemical & Engineering News (C&EN), ACS, weekly newsmagazine, focuses ...
... 2, 2010) SAGE has extended its suite of ... two titles: Therapeutic Advances in Drug Safety , ... Therapeutic Advances in Drug Safety covers novel ... drugs in different age and ethnic patient groups, drug ...
Cached Biology News:Discovery by UC Riverside entomologists could shrink dengue-spreading mosquito population 2