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EMBL-EBI researchers make DNA storage a reality
Date:1/23/2013

longs in the overall code, and make a coding scheme that doesn't allow repeats. That way, you would have to have the same error on four different fragments for it to fail and that would be very rare," says Ewan Birney.

The new method requires synthesising DNA from the encoded information: enter Agilent Technologies, Inc, a California-based company that volunteered its services. Ewan Birney and Nick Goldman sent them encoded versions of: an .mp3 of Martin Luther King's speech, "I Have a Dream"; a .jpg photo of EMBL-EBI; a .pdf of Watson and Crick's seminal paper, "Molecular structure of nucleic acids"; a .txt file of all of Shakespeare's sonnets; and a file that describes the encoding.

"We downloaded the files from the Web and used them to synthesise hundreds of thousands of pieces of DNA the result looks like a tiny piece of dust," explains Emily Leproust of Agilent. Agilent mailed the sample to EMBL-EBI, where the researchers were able to sequence the DNA and decode the files without errors.

"We've created a code that's error tolerant using a molecular form we know will last in the right conditions for 10 000 years, or possibly longer," says Nick Goldman. "As long as someone knows what the code is, you will be able to read it back if you have a machine that can read DNA."

Although there are many practical aspects to solve, the inherent density and longevity of DNA makes it an attractive storage medium. The next step for the researchers is to perfect the coding scheme and explore practical aspects, paving the way for a commercially viable DNA storage model.


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Contact: Mary Todd-Bergman
contactpress@ebi.ac.uk
44-122-349-4665
European Molecular Biology Laboratory
Source:Eurekalert

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