Navigation Links
Drug developed by Hebrew U. and others holds promise for treatment of wounds
Date:2/16/2011

Jerusalem, February 7, 2011 -- A low cost, nanometer-sized drug to treat chronic wounds, such as diabetic foot ulcers or burns, has been developed by a group of scientists from the Hebrew University of Jerusalem, Harvard Medical School and others in the U.S. and Japan.

Diabetes is a rapidly growing medical problem affecting close to 3 percent of the world's population. Poor blood circulation arising from diabetes often results in skin wounds which do not heal, causing pain, infection and at times amputation of limbs.

Several proteins, called growth factors, have been found to speed up the healing process, however purifying these growth factor proteins is very expensive, and they do not last long on the injured site.

Now, scientists at the Hebrew University and Harvard involved in the project have used genetic engineering to produce a "robotic" growth factor protein that responds to temperature. Increasing the temperature causes dozens of these proteins to fold together into a nanoparticle that is more than 200 times smaller than a single hair.

This behavior greatly simplifies protein purification, making it very inexpensive to produce. It also enables the growth factor to be confined and to remain at the burn or wound site. The scientists refer to their discovery as robotic, since just as robots are machines that respond to their environment by carrying out a specific activity, so too this protein they have developed responds and reacts to heat.

The experimental drug, which ha been developed by the research group as a topical ointment, has been patented and thus far has been used to treat chronic wounds in diabetic mice, dramatically increasing the healing rate. The goal is to proceed to human clinical trials at some future date after future tests and refinements.


'/>"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
Source:Eurekalert  

Page: 1

Related biology technology :

1. Human Trial Results Show Plant Extract Tops Drug at Regulating Blood Sugar Levels; Huge Market Seen for Newly Developed Food Additive Emulin™
2. FDA Approves Clinical Studies of a Novel Anti-Cancer Drug Developed by Italian Researchers
3. Designer molecules being developed to fight disease
4. SAFC Supply Solutions(R) Announces Raw Materials Line Developed Specifically to Meet Molecular Diagnostics Manufacturing Requirements
5. New Sigma Advanced Genetic Engineering Labs Offers Research Community Unique Rodent Models Developed Using Exclusive Gene-Editing Technology
6. QIAGENs New Product Line, QIAsafe(R) DNA Blood, has Been Co-Developed With Biomatrica and is Based on Biomatricas SampleMatrix(R) Technology
7. NovaBay(R) Presents Data Confirming Its Aganocide(R) Compounds Are Effective In Killing Bacteria That Have Developed Multidrug-Resistance
8. New lab-on-a-chip technique developed at U of T
9. New nanotech sensor developed with medical, chemistry applications
10. New Program Developed in the Fight Against Feline Aids
11. DuPont Leader: Drought-Tolerant Crops Developed Through Modern Breeding are Key to Sustainably Increasing Grain Production
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Drug developed by Hebrew U. and others holds promise for treatment of wounds
(Date:12/7/2016)... , December 7, 2016 Regen ... the International Journal of Molecular Sciences a team of scientists ... ] have demonstrated that expression of NR2F6 in ... scientists tested for NR2F6 in patient,s cervical cancer tissue as ... tumors. "This is an interesting study and the ...
(Date:12/7/2016)... ... 07, 2016 , ... Proscia Inc., the provider of the ... rapid migration of large pathology data sets to the Proscia Pathology Cloud platform. ... of digital pathology. Proscia’s free massive dataset migrator makes the secure, HIPAA-compliant upload ...
(Date:12/7/2016)... San Francisco, CA (PRWEB) , ... ... ... genomics leader uBiome is opening applications to an early access program for ... power of metagenomic deep-sequencing with the simultaneous specific enrichment and detection of ...
(Date:12/6/2016)... 2016 The American Botanical Council (ABC) ... arnica ( Arnica montana ) through ABC,s Adopt-an-Herb ... HerbMedPro database, a comprehensive, interactive online tool ... research data on the uses and health effects ... Naturopathica, a wellness company with healing arts centers, ...
Breaking Biology Technology:
(Date:12/7/2016)... BOSTON , Dec. 7, 2016   ... today announced the appointment of new CEO ... industry executive with decades of experience, has served ... and Cisco, where he specialized in expanding a ... emerging technology portfolios. He most recently served as ...
(Date:12/2/2016)... India , December 1, 2016 ... Authentication type (Fingerprint, Voice), Future Technology (Iris Recognition ... and Region - Global Forecast to 2021", published ... USD 442.7 Million in 2016, and is projected ... at a CAGR of 14.06%.      ...
(Date:11/29/2016)... , Nov. 29, 2016   ... identification and object recognition technologies, today released ... for fingerprint recognition solutions that run on ... fingerprint template using less than 128KB of ... compact devices that have limited on-board resources, ...
Breaking Biology News(10 mins):