Navigation Links
Dr. Victor Ambros and Dr. Gary Ruvkun Win 2012 Dr. Paul Janssen Award for Biomedical Research for Discovery of MicroRNAs
Date:6/19/2012

BOSTON, June 19, 2012 /PRNewswire/ -- Johnson & Johnson today named Dr. Victor Ambros and Dr. Gary Ruvkun the winners of the 2012 Dr. Paul Janssen Award for Biomedical Research during an event at the Biotechnology Industry Organization International Convention in Boston.  Drs. Ambros and Ruvkun won the Award for their co-discovery of microRNAs (miRNAs) as central regulators of gene expression and development. These regulatory molecules have been implicated in a wide range of normal and pathological activities, including embryonic development, blood-cell specialization, muscle function, heart disease and viral infections. Their discovery has opened new fields of research and has implications for the development of diagnostic tools and medicines.

The Dr. Paul Janssen Award for Biomedical Research was created by Johnson & Johnson to honor the legacy of one of the most passionate, creative and productive scientists of the 20th century, Dr. Paul Janssen (1926-2003).  The legacy of Dr. Paul – as he was known in the scientific community – continues to inspire the company's commitment to developing innovative solutions for unmet medical needs.  Dr. Paul's work led to breakthroughs in several fields, including pain management, psychiatry, infectious disease and gastroenterology.  Four of the drugs discovered by Dr. Paul and his team remain on the World Health Organization's list of essential medicines.

"The groundbreaking research of Dr. Ambros and Dr. Ruvkun has revolutionized the understanding of gene regulation, with significant implications for future developments in the medical field," said Dr. Paul Stoffels, Worldwide Chairman, Pharmaceuticals, Johnson & Johnson.  "Perhaps equally important is the spirit of collaboration exemplified by these researchers – exactly what Dr. Paul advocated in his own labs. Their success demonstrates that we can achieve so much more when we work together, rather than in silos."

Working independently, Dr. Ambros and Dr. Ruvkun led the groups that identified the first miRNA and the first miRNA target.  Dr. Ambros' lab yielded the discovery of the first miRNA and Dr. Ruvkun's lab identified how that miRNA regulates its target messenger.  Working together, they demonstrated that the miRNA inactivates its target through direct, base-pairing interactions.  MicroRNAs have been linked to cancer and identified as regulators of numerous other developmental events in both plants and animals.  As a result of this discovery, researchers are now exploring miRNAs for use in diagnosis and prognosis as well as potential therapies.

"Our research grew out of long-standing traditions in the field aiming to unearth molecular explanations for how biological systems work, with the hope that if an understanding was achieved, practical applications would likely emerge," said Gary Ruvkun, Ph.D., Massachusetts General Hospital and Harvard Medical School.  "We have seen the small RNA field grow from our first papers to thousands of papers, many focused on particular diseases and treatments of diseases.  The research has come full circle – from fundamental biology to medicine – just as we had hoped."

"We are honored to join the distinguished list of past awardees of the Dr. Paul Janssen Award for Biomedical Research," continued Victor Ambros, Ph.D., University of Massachusetts Medical School.  "It is a testament to the wisdom of private and government patrons that fundamental research such as ours was supported over the years, and that it is paying off in new understanding of disease processes…and possibly in cures for patients."

The winners of the Dr. Paul Janssen Award for Biomedical Research are chosen by an independent committee of renowned scientists, including Nobel Laureates and Lasker Prize winners.  The Award, which includes a $100,000 prize, will be presented to Drs. Ambros and Ruvkun in a ceremony followed by a scientific symposium at the New York Academy of Sciences in New York on September 7, 2012.  For more information on the award or to request additional detail on the scientific symposium, please visit www.pauljanssenaward.com.

About The Dr. Paul Janssen Award for Biomedical Research
Dr. Paul Janssen was one of the 20th century's most gifted and passionate researchers.  He helped save millions of lives through his contribution to the discovery and development of more than 80 medicines, four of which remain on the World Health Organization's list of essential medicines.  The Dr. Paul Janssen Award for Biomedical Research was established by Johnson & Johnson to honor the memory of Dr. Paul. Past winners include Craig Mello, Marc Feldmann, Sir Ravinder Maini, Axel Ullrich, Erik De Clercq, Anthony S. Fauci and Napoleone Ferrara.  Learn more at www.pauljanssenaward.com.

About Johnson & Johnson
Caring for the world, one person at a time, inspires and unites the people of Johnson & Johnson. We embrace research and science - bringing innovative ideas, products and services to advance the health and well-being of people. Our approximately 129,000 employees at more than 250 Johnson & Johnson operating companies work with partners in health care to touch the lives of over a billion people every day, throughout the world.

For more information, visit www.jnj.com.

Contact:
Seema Kumar
Janssen Global Services, LLC
908-218-6460 or skumar10@its.jnj.com

Diane Pressman
Janssen Global Services, LLC
908-927-6171 or dpressm1@its.jnj.com

Frederik Wittock
Janssen Global Services, LLC
+32 14 60 57 24 or fwittock@its.jnj.com  

 


'/>"/>
SOURCE Johnson & Johnson
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. BioPower Systems Awarded $5 Million from Victorian Government
2. Janssen Submits Additional Marketing Applications for ZYTIGA® in the U.S. and European Union
3. Charlie Wilson Teams Up With Janssen Biotech to Launch Making Awareness a Priority (M.A.P.)
4. Metamark Genetics Signs Collaboration Agreement on Novel Therapeutic Targets with Janssen Biotech
5. Janssen Biotech, Inc. Announces Collaborative Development and Worldwide License Agreement for Investigational Anti-Cancer Drug, PCI-32765
6. 2011-2012 Michael E. DeBakey Journalism Award Winners Announced
7. Innosight Board Member Honored With Lifetime Achievement Award
8. aTyr Pharma Receives Industry Innovation Awards from TiE and San Diego Venture Group
9. InVigor® Canola Supports the Michigan-Whitman Fire Department with More for Everyone Award
10. Produce Safety Researchers Awarded by ABC Research Laboratories
11. Cohera Medical Awarded Platform Patent on its Biodegradable Adhesive Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... discussions on a range of subjects including policies, debt and ... Poloz. Speaking at a lecture to the Canadian ... to the country,s inflation target, which is set by both ... "In certain areas there needs to be ... why not sit down and address strategy together?" ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... is pleased to announce the launch of their brand, UP4™ Probiotics, into Target ... over 35 years, is proud to add Target to its list of well-respected ...
(Date:6/23/2016)... ... 23, 2016 , ... Charm Sciences, Inc. is pleased to ... AOAC Research Institute approval 061601. , “This is another AOAC-RI approval of the ... Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample tracking software company, ... Crime Laboratory, has joined STACS DNA as a Field Application Specialist. , “I ... President and COO of STACS DNA. “In further expanding our capacity as a scientific ...
Breaking Biology Technology:
(Date:5/24/2016)... May 24, 2016 Ampronix facilitates superior patient care by providing unparalleled technology ... LCD display is the latest premium product recently added to the range of products ... ... ... 3d Imaging- LCD Medical Display- Ampronix News ...
(Date:5/16/2016)... 2016   EyeLock LLC , a market leader ... of an IoT Center of Excellence in ... development of embedded iris biometric applications. EyeLock,s ... and security with unmatched biometric accuracy, making it the ... DNA. EyeLock,s platform uses video technology to deliver a ...
(Date:5/9/2016)... UAE, May 9, 2016 Elevay ... comes to expanding freedom for high net worth professionals ... in today,s globally connected world, there is still no ... could ever duplicate sealing your deal with a firm ... passports by taking advantage of citizenship via investment programs ...
Breaking Biology News(10 mins):