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Dr. John Mendlein Joins aTyr Pharma as Executive Chairman
Date:5/25/2010

resectins, modulate extracellular signaling pathways in a variety of biological processes. Resectins, previously overlooked by genomic efforts due to their hidden intra-protein location in ancient aminoacyl tRNA synthetase genes, have recently been discovered by aTyr, which is leading to connections in human physiology and pathophysiology ranging from inflammation to metabolic disease to peripheral neuropathy to blood disorders. Resectin biology, distinct from currently known pathways and pharmaceutical targets, may represent breakthrough opportunities for novel therapeutic interventions. Tmax, aTyr's first program, is a preclinical replacement protein candidate with a novel thrombopoietic activity for the treatment of thrombocytopenia. aTyr Pharma has established a dominant intellectual property estate surrounding resectin based compositions and therapeutic applications.

The privately held biotech was founded by Dr. Paul Schimmel, a leading aminoacyl tRNA synthetase scientist and biotechnology entrepreneur who also founded Alkermes (ALKS), Cubist (CBST), and Alnylam (ALNY). aTyr Pharma is backed by leading life sciences investors Alta Partners, Cardinal Partners, and Polaris Ventures. For more information please visit www.atyrpharma.com


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