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Dr. John Mendlein Joins aTyr Pharma as Executive Chairman
Date:5/25/2010

tential of the new biology being elucidated with aminoacyl tRNA synthetase resectins."

Dr. Mendlein added, "The genomics efforts missed an important class of extracellular signaling proteins, resectins, which where hiding in the genes of aminoacyl tRNA synthetases, one of the most ancient and biochemically best understood enzyme families in biology. Thanks to aTyr and Dr. Schimmel a new fundamental biology related to intra- and inter-tissue extracellular communication in human physiology hereto unrecognized in medicine is rising up from these ancient, intracellular enzymes. Drug hunting doesn't get any more exciting than new therapeutic intervention points across multiple diseases."

Currently Chairman of Fate Therapeutics and Alevium Pharmaceuticals, Dr. Mendlein has extensive experience shepherding small molecules and biologics from discovery to humans and in building strong, entrepreneurial teams. Previously he was CEO of Adnexus Therapeutics, the leader in the development of a new class of targeted biologics (acquired by Bristol Myers Squibb, BMY). He has served in a variety of senior executive and board roles at both Aurora Biosciences (acquired by Vertex, VRTX) and Affinium Pharmaceuticals; and was a scientist at Smith Kline and French. He has been co-inventor or author of more than 40 issued patents and publications. In various board and executive roles he has been involved with biotech transactions totally over $3.5B in deal value. He received his Ph. D. from the University of California, Los Angeles and his J.D. from the University of California, Hastings.  

About aTyr Pharma

aTyr Pharma engages in the generation of innovative therapeutics based on a new class of naturally occurring human proteins. These proteins, called
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