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Dr. Jeff Jonas Appointed President of Shire Regenerative Medicine Business and Joins Shire Leadership Team
Date:11/15/2012

o obtain and maintain government and other third-party reimbursement for its products; and other risks and uncertainties detailed from time to time in the Company's filings with the Securities and Exchange Commission.

For further information please contact:

Investor Relations      
Eric Rojas    
erojas@shire.com    
+1-781-482-0999

Sarah Elton-Farr    
seltonfarr@shire.com    
+44-1256-894157

Media      
Jessica Mann (Corporate)    
jmann@shire.com    
+44-1256-894-280

Lindsey Hart (Regenerative Medicine)    
lhart@shire.com
+1-615-250-3311



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