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Dr. Audrey F. Jakubowski of SuperGen Retires as Chief Regulatory and Quality Officer

Dr. David S. Smith to Head Regulatory and Quality Affairs

DUBLIN, Calif., Aug. 17 /PRNewswire-FirstCall/ -- SuperGen Inc. (Nasdaq: SUPG), a pharmaceutical company dedicated to the discovery, rapid development and commercialization of therapies for solid tumors and hematological malignancies, today announced that Audrey F. Jakubowski, Ph.D., Chief Regulatory and Quality Officer will retire effective today. Dr. Jakubowski's primary responsibilities have been transitioned to David S. Smith, Ph.D., who earlier this year joined SuperGen as Vice President, Regulatory and Quality Affairs.

"Dr. Jakubowski has been extremely instrumental in guiding and growing SuperGen's regulatory and quality efforts over the years," said Dr. James Manuso, President and CEO. "A valued colleague, Audrey created and nurtured a highly effective organization and approach to regulatory affairs and quality management that the Company will continue under Dr. David Smith's leadership."

Dr. Smith, 52, joined SuperGen in March 2007. Prior to joining SuperGen, Dr. Smith was Senior Director, Regulatory Strategy at Wyeth Consumer Healthcare. His responsibilities included obtaining new product registrations on a global level, US marketed product support, and providing scientific and regulatory guidance to business development initiatives. From 1996 to 2000, Dr. Smith served as Regulatory Affairs Program Director at Roche Pharma. Dr. Smith began his regulatory career in 1987 at Schering-Plough, where he focused on the development and registration of oncology and biotechnology products. During his tenure at Schering-Plough, he concentrated on European Union activities and major markets outside of the U.S. Dr. Smith's training includes a post-doctoral fellowship and research in biochemical genetics at the Roche Institute of Molecular Biology. He received a Ph.D. in pharmacology from Wayne State University School of Medicine, and a B.S. in Biophysics, also from Wayne State University.

About SuperGen

Based in Dublin, Calif., SuperGen, Inc. is a pharmaceutical company dedicated to the discovery, rapid development and commercialization of therapies for solid tumors and hematological malignancies. SuperGen is developing a number of therapeutic anticancer products focused on kinase and cell signaling inhibitors and DNA methyltransferase inhibitors. For more information about SuperGen, please visit


Timothy L. Enns Mary M. Vegh

SuperGen, Inc. SuperGen, Inc.

SVP, Corporate Communications Manager, Investor Relations

& Business Development Tel: (925) 560-2845

Tel: (925) 560-0100

E-mail: E-mail:

SOURCE SuperGen Inc.

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