Navigation Links
Dosing for RVX-208 Phase 1a Clinical Study Completed
Date:4/22/2008

Phase 1a study objectives were met

TSX Exchange Symbol: RVX

CALGARY, April 22 /PRNewswire-FirstCall/ - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that it has completed dosing of its Phase 1a safety, tolerability and pharmacokinetics study for its lead drug candidate, RVX-208, which addresses the dyslipidemia market. "Initial results from the emerging data are very good," declared Donald J. McCaffrey, President & CEO of Resverlogix. "As reported earlier this year the most remarkable results from this study continue to be the outstanding pharmacokinetics (drugability) of RVX-208. With these successful results in hand we are now planning for our Phase 1b/2a trial which, pending discussions and approval from the FDA, we expect to start later this year."

The primary objectives of the Phase 1a trial were to examine the safety, tolerability and pharmacokinetics of RVX-208. This study successfully met those objectives. In addition to the completed Phase 1a human clinical trial, RVX-208 has been the subject of 126 preclinical studies to date, comprising safety, toxicity, pharmacokinetics and pharmacology studies. The Company has selected the dosages to be used in the 28-day Phase 1b/2a study.

"We are very pleased with these promising results which indicate that RVX-208 is a safe and well tolerated drug," stated Dr. Jan Johansson, MD, PhD, Senior Vice President Medical Affairs of Resverlogix. "We are in the process of finalizing the tables, figures and legends for this past study." A review of the pharmacokinetic data was recently presented at the Arteriosclerosis, Thrombosis and Vascular Biology conference in Atlanta, GA.

About Cardiovascular Disease (CVD)

CVD can be generally defined as any abnormal condition characterized by dysfunction of the heart and blood vessels. CVD includes atherosclerosis (especially coronary heart disease which can lead to heart
'/>"/>

SOURCE Resverlogix Corp.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain
2. Nventa completes enrollment and initial dosing of second cohort in Phase 1 HspE7 safety trial
3. Cephalon Reinforces Important Prescribing and Dosing Information for FENTORA
4. FDA Grants Resverlogix Approval to Commence a Phase 1 Clinical Trial for RVX-208
5. Reverse Cholesterol Transport by RVX-208 a Small Molecule for ApoA-I Production Increase Presented at American Heart Association Scientific Meeting
6. Immucor CEOs Italian Trial Moves Toward Second Phase
7. Medarex Reports Phase 1/2 Clinical Data of MDX-060 in Lymphoma at American Association for Cancer Research Meeting
8. BioMS Medicals phase III U.S. multiple sclerosis trial receives positive safety review from Data Safety Monitoring Board
9. AEterna Zentaris Completes Patient Recruitment for First Phase 3 Efficacy Trial with Cetrorelix in Benign Prostatic Hyperplasia
10. Spectrals EAA(TM) to be used in Phase III study for a sepsis anti-endotoxin therapy
11. ThromboGenics Completes Patient Enrolment of MITI IV Trial, a Phase II Study Evaluating the Safety and Preliminary Efficacy of Microplasmin in the Treatment of Acute Stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Md., Sept. 30, 2014 BioHealth Innovation, ... commercializing market-relevant biohealth innovations and increasing access to early-stage ... today that venture capitalist, Tania Fernandez , Ph.D., ... Dr. Fernandez will be a member of the management ... provide up to $50 million in seed and early-stage ...
(Date:9/30/2014)... iLab Solutions announced the results of ... which focuses on core facility operations, growth and utilization ... today. , In its 4th year running, a number ... the year-over-year decrease in the percentage of revenue that ... feeling the constraints of this trend. When asked, “What ...
(Date:9/30/2014)... Springfield, Mo. (PRWEB) September 30, 2014 ... participate at ISPE Boston Product Show 2014. The Boston ... has booked the 23rd annual, day-long event for Wed., ... The show promises to be the largest in ISPE ... scheduled and upward of 3,000 attendees expected. , ...
(Date:9/30/2014)... MA (PRWEB) September 30, 2014 ... (UC) and collaboration company is dedicated to supporting ... connectivity needs. Julie Power, a carrier ... to ensure collaboration solutions stays connected and productive ... to the increased movement of businesses to cloud ...
Breaking Biology Technology:Seasoned Life Sciences Venture Capitalist Tania Fernandez Joins BHI to Help Manage New BioHealth Gap Fund 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 3HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 3SoundConnect Expands Carrier Services Division 2
... , July 23 Applications are now being accepted ... examination. Qualified candidates can take the three-hour exam during the ... globe. , , , ... order to earn the CMPP credential, candidates must meet a defined ...
... NEW YORK , July 22 Reportlinker.com announces that a new market research report ... Bioinformatics Market - Advanced Technologies, ... , , http://www.reportlinker.com/p0243111/Bioinformatics-Market---Advanced-Technologies-Global-Forecast-and-Winning-Imperatives-2009---2014.html ... Report description , ...
... of Nature , scientists from Empa and the Max ... for the first time to grow graphene ribbons that are ... method. Graphene ribbons are considered to be hot candidates for ... width and edge shape. Transistors on the basis of ...
Cached Biology Technology:Applications for the September ISMPP Certified Medical Publication Professional Exam Now Being Accepted 2Applications for the September ISMPP Certified Medical Publication Professional Exam Now Being Accepted 3Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 2Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 3Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 4Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 5Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 6Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 7Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 8Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 9Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 10Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 11Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 12Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 13Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 14Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 15Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 16Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 17Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 18Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 19Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 20Reportlinker Adds Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014) 21Nanoribbons for graphene transistors 2Nanoribbons for graphene transistors 3
(Date:9/29/2014)... PULLMAN, Wash. Scientists at Washington State University ... specifically, Granny Smith apples may help prevent ... be the first to assess these compounds in ... in October,s print edition of the journal ... apples are a good source of these nondigestible ...
(Date:9/29/2014)... online in Behavioral Brain Research provides novel ... a result of chronic alcohol exposure that can lead ... assessments and research indicate that individuals with alcohol use ... occur when people are actively drinking, when they are ... , "Sleep-wake disturbances can last for months, or even ...
(Date:9/29/2014)... years ago when the supercontinent of Pangea was starting to ... entirely different kinds of reptiles called phytosaurs and rauisuchids were ... widely believed the two top predators didn,t interact much as ... ruled the land. But those ideas are changing, thanks largely ... paper published online in September in the German journal ...
Breaking Biology News(10 mins):An apple a day could keep obesity away 2Tooth buried in bone shows prehistoric predators tangled across land, sea 2
... part of Biotesting Europe, a new 358,000 biometrics project, ... that future testing procedures and facilities meet the needs ... growing industry. Biometric recognition systems measure unique behavioural ... as varied as iris images, fingerprints, the structure of ...
... smoking can be harmful, if not deadly. While the desire ... factors also play an important role. The etiology of these ... the environment. Adoption and twin studies have shown that the ... studies have provided evidence that ones sex can influence the ...
... new imaging technique developed at MIT has allowed scientists to ... a method similar to the X-ray CT scans doctors use ... a paper published in the Aug. 12 online edition of ... images yet of what goes on inside a living cell ...
Cached Biology News:UK scientists working to help cut ID theft 2Does the desire to consume alcohol and tobacco come from our genetic makeup? 2Does the desire to consume alcohol and tobacco come from our genetic makeup? 3MIT creates 3-D images of living cell 2
...
HistoScan AP Universal Goat Kit...
Interact with both DNA and RNA; fluorescence green (Em=525 nm) bound to DNA; and fluorescence red (Em=~650 nm) bound to RNA....
One bottle containing 30 ml of protein solution and 0.1% sodium azide....
Biology Products: