New Study Published in the Journal of Rheumatology Examines Quality of Life and Disability in Treatment Failure Gout Patients
EAST BRUNSWICK, N.J., May 5 /PRNewswire-FirstCall/ -- Savient Pharmaceuticals, Inc. (Nasdaq: SVNT) announced today the print publication of the Savient-supported longitudinal observational (non-interventional) study of patients with treatment failure gout (TFG). The objective of the study was to determine the baseline characteristics and natural history of the disease in these patients, who are without treatment options, when under the care of a Board Certified Rheumatologist.
The study is the first to evaluate the quality of life in patients with treatment failure gout and appears in the May issue of the Journal of Rheumatology. TFG is defined as advanced gout in patients where conventional therapy is contraindicated or has been ineffective.
"Our study examined some of the most difficult to treat gout patients, many of whom regularly experience excruciating pain and struggle with co-morbid health disorders like metabolic and cardiovascular disease," said John S. Sundy, MD, PhD, Division of Rheumatology at
Treatment failure gout was shown to be associated with poor health-related quality of life and significant disability. Validated survey instruments for the assessment of patient-reported quality of life were used in this study which included Health Assessment Questionnaire-Disability Index and the SF-36. The TFG patients that were studied averaged 59 years in age. However, due to the poor quality of life associated with the disease, the reported results were more typical of Americans 74 years or older without TFG. Additionally, patient-reported perceptions of their gout-related pain and functioning were even more severe and more consistent than assessments of these same metrics reported by physicians.
About Savient Pharmaceuticals, Inc.
Savient Pharmaceuticals, Inc. is a specialty biopharmaceutical company focused on developing and marketing pharmaceutical products that target unmet medical needs in both niche and broader specialty markets. Savient's product development candidate, KRYSTEXXA(TM) (pegloticase) for treatment failure gout, has reported positive Phase 1, 2 and 3 clinical data. Patient dosing in the Phase 3 clinical studies began in June 2006; patient enrollment was completed in March 2007; and the Phase 3 clinical studies were completed in October 2007. The BLA was filed with the FDA in October 2008; granted priority review status in December 2008; and the review period was extended by three months in February 2009. Savient has exclusively licensed worldwide rights to the technology related to KRYSTEXXA, formerly referred to as Puricase(R), from
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Contact: Mary Coleman Savient Pharmaceuticals, Inc. email@example.com (732) 418-9300 Christina Gibson Euro RSCG Life Worldwide firstname.lastname@example.org (212) 367-6818
|SOURCE Savient Pharmaceuticals, Inc.|
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