Navigation Links
DioGenix' MSPrecise Identifies Early-Stage Patients with Multiple Sclerosis
Date:11/8/2012

GAITHERSBURG, Md., Nov. 8, 2012 /PRNewswire/ -- DioGenix, Inc., a company developing molecular diagnostics for the early diagnosis and monitoring of immune-mediated neurological diseases, today announced its lead product MSPrecise™ outperformed the specificity of the current standard of care for cerebral spinal fluid (CSF) analysis in patients suspected of having multiple sclerosis (MS) by almost two to one with no loss of sensitivity. MSPrecise is a proprietary next-generation sequencing assay that analyzes changes in key genes involved in the adaptive immune system of patients being evaluated for MS. The results of this clinical study are consistent with two prior DioGenix studies, all of which compared MSPrecise results both to published performance data for the oligoclonal banding test and experimental controls.

Patients that present with clinical symptoms and evidence of inflammation and damage to the myelin sheath that surrounds and protects nerve fibers in the CNS undergo a battery of tests in a diagnostic process that can take months to years to complete. The diagnostic standard of care for MS includes CSF analysis using the oligoclonal banding test, which detects immunoglobin G proteins that indicate an immune response within the CNS. Because the oligoclonal banding test yields a high rate of false positive results, confident diagnosis also requires a comprehensive set of clinical tests including magnetic resonance imaging and, in certain cases, visual evoked potentials. Due to the variability of symptoms between patients and the lack of a definitive test, it has been estimated that the misdiagnosis rate for MS is higher than any other immune-mediated neurological disease.

"The results of our most recent study continue to support our belief that MSPrecise will be an important new tool in the management of patients suffering with MS. We have clearly demonstrated, in a series of clinical studies, the pow
'/>"/>

SOURCE DioGenix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. From lectures to explosives detection: Laser pointer identifies dangerous chemicals in real-time
2. Parthenon Identifies Emerging Opportunities in Targeted Payload Cancer Therapeutics
3. Corporate Venturing and Early-Stage Financing in the Spotlight at BioTrinity
4. Access BridgeGap Ventures to Focus on Early-Stage Therapeutic Opportunities
5. Multimodal Treatment of Peritoneal Metastases Offers Hope for Many Patients With Colorectal Cancer
6. Stem Cells Bring New Hope for Parry-Romberg Syndrome Patients
7. Sosei Group Corporation QVA149 Phase III Study Meets Primary Endpoint in Reducing Exacerbations in COPD Patients and Filings in EU and Japan by End of Year
8. Study of Cell Therapeutics Tosedostat for Elderly Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome Now Enrolling
9. Acute Lymphocytic Leukemia: Impressive Results With the Monoclonal Antibody Blinatumomab in Patients With Refractory Disease
10. How Malignant Cells in Patients With Chronic Lymphocytic Leukemia Escape T Cell Recognition and Attack
11. Sangart Raises Additional $50M Series G Funding Following Interim Safety Analysis Of Phase 2b Study Of MP4OX In Severe Trauma Patients With Hemorrhagic Shock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... Biotech companies make announcements illustrating ... systems and advanced Laboratory Instrumentation. Companies in focus today ... BDX ), Thermo Fisher Scientific Inc. (NYSE: ... RGDO ), Sangamo Biosciences Inc. (NASDAQ: SGMO ... BioSciences, Inc. (OTCQB: PBIO) ("PBI" or the "Company") today ...
(Date:9/19/2014)... Pfenex Inc. (NYSE MKT: PFNX), a clinical-stage ... difficult to manufacture proteins including biosimilar therapeutics, today announced ... Annual NewsMakers in the Biotech Industry conference in ... , chief executive officer of Pfenex, will provide an ... on Friday, September 26, 2014 at 10:00 a.m. EDT/7:00 ...
(Date:9/19/2014)... NC (PRWEB) September 19, 2014 ... Biobased Product Label for its Organic Cotton . ... product’s amount of renewable biobased ingredients meets or exceeds ... intermediate materials composed in whole or in significant part ... logo/label will allow our Organic cotton to be immediately ...
(Date:9/19/2014)... September 19, 2014 ... http://www.researchandmarkets.com/research/b2jxhs/micro_market ) has announced the addition of the  ...  report to their offering.       (Logo: ... one of the fastest-growing segments in the chromatography ... in 2013, and expected to reach $2.0 billion ...
Breaking Biology Technology:Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 2Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 3Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 4Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 5Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 6Medical Instrumentation Automation Advances for Biological Sample Preparation - Company Expects Q4 Revenue Impact from Newest Instrument Systems 7Pfenex to Present at Upcoming Industry Conference on September 26 2Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2Micro Market Monitor : Global Pre-packed Chromatography Columns 2
... , , ... , , , ... analysis.,By comparing the separated bands,of an unknown sample to a ... fragment,can be estimated. The Agilent,2100 bioanalyzer is an instrument,which utilizes ...
... , , ... , , , Whereas in ... molecules, the development of soft ionization methods,such as matrix-assisted laser desorption/ionization ... the analysis of proteins up to 300 kDa using MS has,become ...
... , , , ... , , , , ... studying functional,assays requiring the transfection of small interfering RNA (siRNA),into a cell, ... given cell lines would be of great value.,Three to four siRNA sequences ...
Cached Biology Technology:High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 2High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 3High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 4High resolution DNA analysis with the,DNA 500 and DNA 1000 LabChip kits 5Using the Agilent 2100 bioanalyzer for,quality control of protein samples prior to,MS-analysis 2Using the Agilent 2100 bioanalyzer for,quality control of protein samples prior to,MS-analysis 3Using the Agilent 2100 bioanalyzer for,quality control of protein samples prior to,MS-analysis 4Using the Agilent 2100 bioanalyzer for,quality control of protein samples prior to,MS-analysis 5siRNA transfection optimization,with the Agilent 2100 bioanalyzer 2siRNA transfection optimization,with the Agilent 2100 bioanalyzer 3siRNA transfection optimization,with the Agilent 2100 bioanalyzer 4siRNA transfection optimization,with the Agilent 2100 bioanalyzer 5siRNA transfection optimization,with the Agilent 2100 bioanalyzer 6siRNA transfection optimization,with the Agilent 2100 bioanalyzer 7
(Date:9/18/2014)... are too stressed they are often grouchy, grumpy, nasty, ... (BMI) at EPFL have just highlighted a fundamental synaptic ... the loss of social skills and cognitive impairment. When ... molecule in the brain. This was revealed by a ... Carmen Sandi,s team went to look for answers in ...
(Date:9/18/2014)... can swim up to 400 kilometres in search of a ... change. , Clownfish spend their entire adult lives under the ... wander the open ocean, says study co-author, Dr Hugo Harrison ... (Coral CoE) at James Cook University. , "In the past ... given a rare glimpse into how far they can swim, ...
(Date:9/17/2014)... the creation of the Santa Ana Wildfire Threat Index ... potential of the powerful, hot, dry Santa Ana wind, ... index was introduced Sept. 17 by the U.S. Forest ... and Electric. , The index includes four classification levels ... to help fire agencies and other emergency responders, the ...
Breaking Biology News(10 mins):How stress tears us apart 2Nemo's epic journey to find a new home 2UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2
... obtained the first detailed molecular structure of a member of ... for the field of epigenetics because Tet enzymes chemically modify ... is shut off" into other signs that say "ready for ... only in the last five years; they are needed for ...
... have completed a comprehensive genomic analysis of cervical cancer ... mutations not previously found in cervical cancer, including at ... for other forms of cancer. The findings also shed ... the development of cervical cancer. The study, ...
... the largest international study to date into the genetic basis ... disease and provide evidence that large-scale genetic studies can assist ... as rheumatoid arthritis. The study, conducted by Dr. Robert ... Institute in the USA and Dr. Yukinori Okada from the ...
Cached Biology News:Epigenetics enigma resolved 2International team completes systematic, genomic study of cervical cancer 2International team completes systematic, genomic study of cervical cancer 3International team completes systematic, genomic study of cervical cancer 4International team completes systematic, genomic study of cervical cancer 5Rheumatoid arthritis research shows the potential of large-scale genetic studies for drug discovery 2
... for ambient HPLC. Contains connections and ... two external devices such as RI ... analog output from the 90 detector ... Includes an input for synchronization with ...
...
...
... Experion StdSens reagents and supplies, for ... supplies sufficient to perform standard-sensitivity RNA ... on the Experion automated electrophoresis system. ... 20 microliters RNA StdSens stain, 20 ...
Biology Products: