Navigation Links
Differing structures underlie differing brain rhythms in healthy and ill
Date:10/14/2011

r airports and a large number of smaller airports with only a few connections." In the brain model, the airports are called nodes and in the healthy model, about 10 percent of nodes are hubs.

In the real brain, the prefrontal cortex, which is a center for complex thought, social behavior and more, is a hub. "It is thus reasonable to think that the functional connectivity of the prefrontal cortex is altered in pathologies like schizophrenia", said Galn.

Indeed, the network in the epileptic brain model is less complex than the healthy model and the network in the schizophrenia model is even less so. The result is that the dominance of the hubs falls off, which may be indicative of a neuropathology or mental illness, the researchers say.

Their analysis reveals that oscillating brain activity in the virtual models appear to emerge from interactions among neurons and not from so-called pacemakers, which some researchers hypothesize are specialized neurons generating different rhythms of activity in the brain.

This information, combined with finding that healthy brain rhythms are not homogeneously distributed across all virtual brain nodes, supports the idea that oscillations may be a mechanism linking perceptual information across sensory and associative areas of the brain, the researchers say.

Galn and Steinke also discovered that nodes receiving the greatest input produced the smallest fluctuations in activity in the healthy and epileptic brain models. But the inverse relationship was not seen in the schizophrenic model.

The researchers have made the computer programs that run their algorithms and simulations available free to clinicians and other investigators who want to test the predictions made by the models or to expand their own studies. They are included in the supplemental materials, along with technical instructions supplied with the paper or at http
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Carbon nanotube structures changed by attack from within, researchers discover
2. Heated AFM tip allows direct fabrication of ferroelectric nanostructures on plastic
3. UBC researchers develop new model to predict the optical properties of nano-structures
4. Trapping a rainbow: Lehigh researchers slow broadband light waves with nanoplasmonic structures
5. Intricate, curving 3-D nanostructures created using capillary action forces
6. High-speed filter uses electrified nanostructures to purify water at low cost
7. Unprecedented look at oxide interfaces reveals unexpected structures on atomic scale
8. Empa grows sea urchin-shaped structures
9. Depth charge: Using atomic force microscopy to study subsurface structures
10. Biomedical Structures Receives Growth Capital from Ampersand Ventures to Fund Ongoing Expansion
11. Light twists rigid structures in unexpected nanotech finding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... and NEW YORK , ... PTBI, PTBIW), a biopharmaceutical company advancing patient care in ... offering of 3,500,000 shares of common stock, and warrants ... common stock, at an offering price of $4.00 per ... per share exercise price of $5.00, are exercisable immediately, ...
(Date:12/24/2014)... Earlier this year in a June 24 international ... Adult Stem Cell Technology Center, LLC ( ASCTC ) ... unique property of adult tissue stem cells. His ... the Past, Important for the Future,” embodied the essence ... the address at the 4th World Congress on Cell ...
(Date:12/24/2014)... Nashville Fertility Center announced that Dr. George ... Society for Reproductive Medicine (ASRM), a leading professional organization ... In his new role as treasurer, Dr. Hill ... will have a voice in furthering the mission of ... since 1984 when he joined while conducting fellowship training ...
(Date:12/24/2014)... PharmaBoardroom,s new report, , Healthcare and ... free download , digs deep into this vibrant market, ... sector today. One area where Algeria ... a homegrown pharmaceutical manufacturing base, even if the government,s ambitious ... off. A cursory comparison with neighboring Morocco ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3
... Inc. launched Tinidazole 500, the first generic version of ... oral antimicrobial drug approved by the FDA for the ... BioComp Pharma will begin shipping the generic version ... active ingredients and efficacy as branded drugs but, on ...
... Key Secondary Endpoints -- CAPACITY 1 Misses Primary Endpoint, ... and MAA -BRISBANE, Calif., Feb. 3 InterMune, Inc. ... the two Phase 3 CAPACITY studies evaluating pirfenidone in ... endpoint of change in percent predicted Forced Vital Capacity ...
... feat for any company. Last year, Alkemists Labs reaped the benefit ... at the right time" and showed year over year sales growth of ... ... Sudberg, Founder, CEO and Chief Scientific Officer of Alkemists Labs proudly announces ...
Cached Biology Technology:BioComp Pharma Launches First Generic Drug for Tindamax(R) 2BioComp Pharma Launches First Generic Drug for Tindamax(R) 3InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 2InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 3InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 4InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 5InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 6InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 7InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 8InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 9InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 10InterMune Reports Results of Two Phase 3 CAPACITY Studies of Pirfenidone in IPF 11Alkemists Labs Wins Nutrition Business Journal's 2008 Industry Growth Award 2Alkemists Labs Wins Nutrition Business Journal's 2008 Industry Growth Award 3
(Date:12/22/2014)... 22, 2014 Research and Markets ... addition of the "The Global Watermarking ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... overview of the global digital media watermarking ... and monitor piracy by securely and invisibly ...
(Date:12/19/2014)... and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced ... America Perimeter Security Systems Market" report to their ... The North American perimeter security market is estimated ... to 2019. Although the U.S. market holds a larger ... is expected to grow at a higher CAGR of ...
(Date:12/17/2014)... Research and Markets ( http://www.researchandmarkets.com/research/s6qzt5/samsung_galaxy_s5 ... "Samsung Galaxy S5 - Home Button Synaptics Fingerprint ... http://photos.prnewswire.com/prnh/20130307/600769 ... than the iPhone 5S, Samsung introduces for the ... The Galaxy S5 home button presents ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2
... ranging from medical devices such as MRIs to surveillance balloons ... 1996, Congress directed the government to sell essentially all of ... for its investment in the helium and its storage. ... the National Research Council, assesses whether selling off the reserve ...
... performance on a video game simply by measuring the volume ... this week. The new study, in the journal ... variability in achievement seen among men and women trained on ... volume of three structures in their brains. The study ...
... the exploration of the human mind in the hope ... origin of thought to the nature of knowledge. Today ... emerging fields of research in various areas, an approach ... project from Wiley-Blackwell. The content of this journal will ...
Cached Biology News:Video gamers: Size of brain structures predicts success 2Video gamers: Size of brain structures predicts success 3
... years of expertise in the field of ... the most powerful systems on the market. ... 000 in-microplate tests requiring incubation and washing ... modules (such as worktable shaker incubators, reader,washer), ...
... pre-validated SNP sequencing services ... within 93 genes including ... more than 80 tyrosine ... were developed and validated ...
... Mouse anti-Yersinia pestis F1 antigen, ... Applications: ELISA: Use at ... at an assay dependent dilution. WB: ... Predicted molecular weight: 18 kDa. Not ...
... Fixation medium Reagent B - Permeabilisation medium ... cells in suspension with Reagent A and ... This procedure gives antibodies access to intracellular ... of the cells intact. Specific formulations reduce ...
Biology Products: