Navigation Links
Differing structures underlie differing brain rhythms in healthy and ill
Date:10/14/2011

r airports and a large number of smaller airports with only a few connections." In the brain model, the airports are called nodes and in the healthy model, about 10 percent of nodes are hubs.

In the real brain, the prefrontal cortex, which is a center for complex thought, social behavior and more, is a hub. "It is thus reasonable to think that the functional connectivity of the prefrontal cortex is altered in pathologies like schizophrenia", said Galn.

Indeed, the network in the epileptic brain model is less complex than the healthy model and the network in the schizophrenia model is even less so. The result is that the dominance of the hubs falls off, which may be indicative of a neuropathology or mental illness, the researchers say.

Their analysis reveals that oscillating brain activity in the virtual models appear to emerge from interactions among neurons and not from so-called pacemakers, which some researchers hypothesize are specialized neurons generating different rhythms of activity in the brain.

This information, combined with finding that healthy brain rhythms are not homogeneously distributed across all virtual brain nodes, supports the idea that oscillations may be a mechanism linking perceptual information across sensory and associative areas of the brain, the researchers say.

Galn and Steinke also discovered that nodes receiving the greatest input produced the smallest fluctuations in activity in the healthy and epileptic brain models. But the inverse relationship was not seen in the schizophrenic model.

The researchers have made the computer programs that run their algorithms and simulations available free to clinicians and other investigators who want to test the predictions made by the models or to expand their own studies. They are included in the supplemental materials, along with technical instructions supplied with the paper or at http
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Carbon nanotube structures changed by attack from within, researchers discover
2. Heated AFM tip allows direct fabrication of ferroelectric nanostructures on plastic
3. UBC researchers develop new model to predict the optical properties of nano-structures
4. Trapping a rainbow: Lehigh researchers slow broadband light waves with nanoplasmonic structures
5. Intricate, curving 3-D nanostructures created using capillary action forces
6. High-speed filter uses electrified nanostructures to purify water at low cost
7. Unprecedented look at oxide interfaces reveals unexpected structures on atomic scale
8. Empa grows sea urchin-shaped structures
9. Depth charge: Using atomic force microscopy to study subsurface structures
10. Biomedical Structures Receives Growth Capital from Ampersand Ventures to Fund Ongoing Expansion
11. Light twists rigid structures in unexpected nanotech finding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2013 was a banner year of continued innovation ... continued independent research led by the team at Wake ... million grant from the Susanne Marcus Collins Foundation, had ... reviewed journal, Amy Grant highlighted Brainwave Optimization® in First ...
(Date:1/14/2014)... PA (PRWEB) January 14, 2014 Date: Friday, ... , Location: Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... national nonprofit organization solely dedicated to finding a cure for ... affected worldwide, will host its annual Crystal Ball on Friday, ...
(Date:1/14/2014)... owners drew up their lists of New Year,s resolutions for 2014, ... my furry companion." Nowadays there are pet salons, dog and cat ... the little canine or feline darlings along wherever mommy or daddy ... toys at the pet store. But anyone who has ever lived ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility management software, today ... In this role, Michelle will work with current and potential ... development of iLab products. Her main goal will be to ... scientific community by offering the most advanced, user-friendly, and high-impact ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... ARBOR, Mich., Sept. 13 MichBio, the ... its 2007/8 Michigan Life,Sciences Directory and Resources ... sciences companies. The guide includes editorial pages ... the University,Research Corridor, the Michigan Universities Commercialization ...
... Mo. and FREDERICK, Md., Sept. 13 /PRNewswire-USNewswire/,-- To ... services,Midwest Research Institute (MRI) announced today the launch ... -- a center staffed by an,internationally recognized team ... to provide a diverse range of specialized,laboratory consulting ...
... Multiplexing Technology Symposium Brings Together Thought Leaders,in Life ... Best Practices, OOSTERHOUT, Netherlands, Sept. 13 ... in multiplexed solutions,today announced the agenda for Planet ... symposium. The two-day event will be,held 2-3 October ...
Cached Biology Technology:Midwest Research Institute Launches Center for Biological Safety and Security (CBS2) 2Luminex Corporation Hosts the Fifth Annual Planet xMAP Europe 2007 Symposium 2Luminex Corporation Hosts the Fifth Annual Planet xMAP Europe 2007 Symposium 3
(Date:4/24/2014)... has been published in the Scientific Reports journal. ... Biology (a joint centre of CSIC and Pompeu Fabra University-UPF), ... decoded and we saw that it did not match with ... to sequence the complete genome and to make a functional ... belong to Louis XVI". , The functional genome analysis ...
(Date:4/24/2014)... representing the largest study of animal intelligence to-date finds that ... , Published this week in the journal Proceedings of ... of a long history of research aimed at understanding the ... things like make and use tools, read social cues, or ... now, most studies of animal intelligence have focused on only ...
(Date:4/24/2014)... WASHINGTON, April 24A droplet of clear liquid can bend ... well-known phenomenon, researchers have developed a new process to ... than a penny apiece. , Because they,re so ... of applications, including tools to detect diseases in the ... and microscopes for education in classrooms. , "What ...
Breaking Biology News(10 mins):The blood preserved in the pumpkin did not belong to Louis XVI 2Animals with bigger brains, broader diets have better self control 2Animals with bigger brains, broader diets have better self control 3Bake your own droplet lens 2Bake your own droplet lens 3
... An Arizona State University research team has developed a ... renewable biofuels. The team has programmed a photosynthetic ... their biofuel byproducts--easier and potentially less costly. ... harvesting the goodies and turning them into fuel," said ...
... diffraction is a step closer to fulfilling its ... biological samples. In the Proceedings of the ... in applying an approach to "lensless" X-ray microscopy ... produced the first images, using this technique, of ...
... For more than 400 years, scientists have studied ... how these creatures routinely repair injuries that would usually ... Now, fueled by a highly competitive National Institutes ... multi-institutional team of researchers associated with the University of ...
Cached Biology News:Self-destructing bacteria improve renewable biofuel production 2Self-destructing bacteria improve renewable biofuel production 3Researchers demonstrate nanoscale X-ray imaging of bacterial cells 2$2.4 million stimulus fuels effort to regenerate injured spinal cords 2$2.4 million stimulus fuels effort to regenerate injured spinal cords 3$2.4 million stimulus fuels effort to regenerate injured spinal cords 4
... Multipeptide Kit, designed for use with ... variety of amyloid peptides more straightforward ... Clinical neuroscience proteomics applications - Monitor ... Correlate beta-amyloid peptide levels with disease ...
... hybridization chamber assembly (1 each) Components ... chamber user guide plastic tweezersChambers are ... cleaned and reused. The chamber is designed ... kits and all custom oligo microarrays, in ...
... Formula variant: With the ... described by Hoagland and ... Equivalency: Formulated to contain ... powder per liter of ...
... For separation and fractionation of ... of nuclei from cytosolic proteins ... complexity, greatly facilitating study of ... nucleic acid binding proteins (e.g., ...
Biology Products: