Navigation Links
Differing structures underlie differing brain rhythms in healthy and ill
Date:10/14/2011

Virtual brains modeling epilepsy and schizophrenia display less complexity among functional connections, and other differences compared to healthy brain models, researchers at Case Western Reserve University School of Medicine report.

The researchers worked backward from brain rhythms the oscillating patterns of electrical activity in the brain recorded on electroencephalograms - from both healthy and ill individuals.

These oscillations relate to the state of awareness. But, instead of seeking answers to how the rhythms emerge, the investigators built models that, when they reproduced the different neural activity patterns seen in real brains, revealed underlying structural differences among the healthy and ill.

Their work is published in the online journal PLoS Computational Biology.

"Our hypothesis is that healthy brains share features with the virtual healthy brains and unhealthy brains share features with virtual unhealthy brains," said Roberto Fernndez Galn, a professor of neurosciences at Case Western Reserve School of Medicine. Galn has a background in physics, electrophysiology and computational neuroscience.

Galn worked with G. Karl Steinke, a former graduate student in Biomedical Engineering at Case School of Engineering, and now a researcher at Boston Scientific Neroumodulation.

After breaking down the oscillating patterns of brain activity collected from real EEGs and MEGs into a usable form, the researchers applied inverse calculations and reverse engineering to develop brain models they refer to as virtual brains.

The most striking difference they found is in the hierarchical networks of brain connections among the models of healthy and unhealthy brains, Galn said. "The more complex the network, the more normal the EEG pattern."

"A healthy brain network is similar to the airport network," he explained. "There are a small number of hubs with many connections to othe
'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Carbon nanotube structures changed by attack from within, researchers discover
2. Heated AFM tip allows direct fabrication of ferroelectric nanostructures on plastic
3. UBC researchers develop new model to predict the optical properties of nano-structures
4. Trapping a rainbow: Lehigh researchers slow broadband light waves with nanoplasmonic structures
5. Intricate, curving 3-D nanostructures created using capillary action forces
6. High-speed filter uses electrified nanostructures to purify water at low cost
7. Unprecedented look at oxide interfaces reveals unexpected structures on atomic scale
8. Empa grows sea urchin-shaped structures
9. Depth charge: Using atomic force microscopy to study subsurface structures
10. Biomedical Structures Receives Growth Capital from Ampersand Ventures to Fund Ongoing Expansion
11. Light twists rigid structures in unexpected nanotech finding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... computers have yet to materialise. Yet, scientists are ... such computers faster. One such approach relies on ... by applying an electric field. A new study ... coupled quantum dots (TQDs) with electrical impulses can ... example, should TQDs be used as quantum information ...
(Date:7/24/2014)... to settle into equilibriuma state of unchanging balance ... of non-equilibrium conditions where new possibilities lie. Non-equilibrium ... such as temperature fluctuations, freezing and melting, or ... body temperature, airplanes to fly, and the Earth ... even though these conditions exist naturally and are ...
(Date:7/24/2014)... , July 24, 2014 Research and ... "Global Genomics and Proteomics Analytical Instruments Market 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 Genomics is the study of ... study of the structure and functions of proteomes or ... tools and technology. Genomics involves the mapping of genes ...
(Date:7/24/2014)... SRI International has been awarded a new ... Allergy and Infectious Diseases (NIAID), part of the National ... therapies for HIV infection and AIDS. The contract supports ... and the complications and opportunistic infections associated with the ... of HIV. According to the World ...
Breaking Biology Technology:New approach to form non-equilibrium structures 2Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3
... Inc. (NASDAQ: VVUS ) today announced that Timothy ... company at the 2011 BioCentury NewsMakers in the Biotech Industry ... the Millennium Broadway Hotel in New York, NY on Friday, ... and 30-day archive of the presentation will be available at ...
... that twist like the trunk of an elephant, but provide ... Oct. 13 for a publication in Science magazine ... at Dallas, The University of Wollongong in Australia, The University ... These muscles, based on carbon nanotubes yarns, accelerate a ...
... Calif., Oct. 13, 2011 Amgen (NASDAQ: AMGN ... Robert A. Bradway to the Company,s Board.  Bradway, 48, is ... brings the number of Amgen board members to 13. ... Strategy and served as executive vice president and chief financial ...
Cached Biology Technology:Carbon nanotube muscles generate giant twist for novel motors 2Carbon nanotube muscles generate giant twist for novel motors 3Amgen Appoints Robert A. Bradway to the Company's Board of Directors 2
(Date:7/25/2014)... Ravi Birla, associate professor of biomedical engineering at ... textbook on tissue engineering and artificial organ development., ... a comprehensive guide to entering into the field ... and professor of biomedical engineering at UH, served ... said that while there are other published books ...
(Date:7/25/2014)... which is derived from diffusion tensor imaging (DTI), ... such as the corticospinal tract, the rubrospinal tract, ... tract is known to be a major neural ... Several studies have reported on injury of the ... studies have demonstrated recovery of a corticospinal tract ...
(Date:7/25/2014)... Biometrics industry expands and becomes ... technology for online & commerce payments while seeking security ... GOOG ), LifeLock Inc. (NYSE: LOCK ... Inc. (NASDAQ: AAPL ) and Fortinet Inc. ... biometric authentication company focused on the growing m-commerce market, ...
Breaking Biology News(10 mins):University of Houston researcher publishes textbook on tissue engineering 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 3Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 4Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 5Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 6
... two of the hottest fields in research, investment, ... Next Industrial Revolution." , But how ... U.S. public feel that the potential benefits of ... trust to monitor the safety of new technologies? ...
... (NIH) has selected the first projects to be ... Health Initiative (GEI), a unique collaboration between geneticists ... research in understanding the complex factors that contribute ... and Human Services Secretary Mike Leavitt. "Researchers have ...
... REDWOOD SHORES, Calif., Aug. 14 Communication,Intelligence Corporation ... leading supplier of electronic signature solutions for,business process ... in biometric signature verification, announced today its financial,results ... 30, 2007. Total revenue of $555,000 for ...
Cached Biology News:Nanotechnology: What's that? 2Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 2Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 3Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 4Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 5Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 6Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 7Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 8Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring 9Communication Intelligence Corporation Reports Second Quarter 2007 Financial Results 2Communication Intelligence Corporation Reports Second Quarter 2007 Financial Results 3Communication Intelligence Corporation Reports Second Quarter 2007 Financial Results 4Communication Intelligence Corporation Reports Second Quarter 2007 Financial Results 5
activating transcription factor 4 (tax-responsive enhancer element B67),...
Request Info...
2-min, single-step add-mix-measure assay for luciferase expression and HTS in mammalian cells. Linear detection range: 2 fg to 46 ng luciferase....
Trop-2 Purified Anti-Human clone 162-46, Isotype Mouse IgG 1 , 100 µg Consult technical datasheet for details....
Biology Products: