Navigation Links
Diagenode Releases Two New Epigenetic Monoclonal 5-hmC Antibodies for Quantifying Global Hydroxymethylation
Date:9/22/2010

LIEGE, Belgium, Sept. 22 /PRNewswire/ -- Diagenode announced today that it has released two additional 5-hmC antibodies to complement its original 5-hmC (rat) monoclonal antibody. The two new 5-hmC monoclonal antibody (mouse) and polyclonal antibody (rabbit) antibodies give researchers additional choices for enriching and analyzing 5-hmC in their methylation studies.

(Photo: http://photos.prnewswire.com/prnh/20100922/NY69887 )

(Photo: http://www.newscom.com/cgi-bin/prnh/20100922/NY69887 )

The importance of 5-hmC to the epigenetic field was highlighted in a recent Epigenie review: "A year after 5-hydroxymethylcytosine's (5-hmC) dramatic entrance into the epigenetics research scene, the research community has a long list of questions to ask about the 6th base. Investigations into 5-hmC were sidelined for most of the year due to the absence of methods to analyze it. Thankfully those helpless days are history as Diagenode just launched the first 5-hmC monoclonal antibody, an innovation that makes enriching and analyzing 5-hmC a reality." (www.epigenie.com, May 11, 2010) 

These latest additions make available the broadest range of validated methylation products to the research community. Prior to this, there were no other validated antibodies available in the market for routinely identifying 5-hmC and discriminating this base from 5-mC. Diagenode and collaborators have extended validation of the 5-hmC antibody from the standard Dot Blot and Immunofluorescence approaches to hMeDIP, and hMeDIP-Seq profiling.

What is truly exciting for researchers is they will now be able to perform Dual MeDIP Assays with multiple choices of 5-hmC antibodies (Diagenode's hMeDIP kit), first by utilizing the 5-hmC monoclonal or polyclonal antibody in hMeDIP, and then the Diagenode monoclonal 33D3 MeDIP Assay (Diagenode's MeDIP kit). This approach will allow researchers to profile both types of cytosine marks in one experiment.  

Diagenode was founded in 2003. Its research and development division is continually improving its technical knowledge of DNA methylation as evident in Diagenode's Methylated DNA Immunoprecipitation (MeDIP), Bi-Sulfite, Methyl binding domain (MBD) protein (also known as MethylCap) and the gold standard 33D3 5-methylcytosine antibody (5-mC) offerings.

About Diagenode

Diagenode is a multinational life science company that develops and commercializes innovative instruments and reagents for epigenetic research. Major product lines include; IP-Star ® Automation, Bioruptor® Sonication, epigenetic targeted antibodies & kits, and methylation. Founded in 2003 in Liege (Belgium), Diagenode has offices in Liege, Belgium and Denville, New Jersey.

www.Diagenode.com


'/>"/>
SOURCE Diagenode
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Health Robotics Releases Results of First 20 i.v.STATIONs Return On Investment (ROI) Studies in the USA and Canada
2. Promega Releases 2009 Corporate Sustainability Report
3. Arrowhead Releases New Report Assessing State of Personalized Medicine Market
4. Hayes, Inc. Releases Guide to BRCA1 and BRCA2 Genetic Testing
5. MD Bioproducts Releases a New Mouse T1/ST2 ELISA
6. Centrifuge Releases New Data Visualization Software
7. Sunlight Research(TM), Releases its Osiris Therapeutics Stem Cell Patent Report
8. VKernel Releases Optimization Pack 1.2
9. Datafarm Releases New Desktop-based Application for Multi-region Viewing of eCTD Submissions: Datafarm VUE
10. SCDM Releases Best Practices for Automated Data Cleaning
11. Signatec Releases PX1500-4, Its 4-Channel, 1.5 GHz Per Channel / 2-Channel, 3 GHz Per Channel PCI-Express Digitizer with Two Virtex-5 FPGAs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... May 24, 2016 , ... Cell therapies ... will be accelerated by research at Worcester Polytechnic Institute (WPI) that yielded a ... and tissue regeneration. , The novel method, developed by WPI faculty members Raymond ...
(Date:5/23/2016)... ... May 23, 2016 , ... PrecisionAg® Media has ... 2017 and Beyond. The paper outlines the key trends that are creating both ... “We’ve witnessed a lot of highs and lows as the precision agriculture market ...
(Date:5/23/2016)... ... May 23, 2016 , ... ... focused on molecular nanotechnology, announced the winners for the 2015 Foresight Institute Feynman ... Feynman, are given in two categories, one for experiment and the other for ...
(Date:5/20/2016)... ... ... The recent recall by Costco and Trader Joes of 47 million pounds of ... demonstrates the need for faster and more cost effective bio-threat detection to ensure food ... , PathSensor’s latest solution uses a biosensor technology called CANARY®. CANARY®, an ...
Breaking Biology Technology:
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... of Infosys (NYSE: INFY ), and Samsung SDS, ... partnership that will provide end customers with a more ... payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) ... financial services, but it also plays a fundamental part in ...
(Date:4/15/2016)... 15, 2016  A new partnership announced today ... underwriting decisions in a fraction of the time ... and high-value life insurance policies to consumers without ... With Force Diagnostics, rapid testing (A1C, Cotinine and ... (blood pressure, weight, pulse, BMI, and activity data) ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys has ... CEO, Barrett Bready , M.D., who returned to ... the original technical leadership team, including Chief Technology Officer, ... Product Development, Steve Nurnberg and Vice President of Software ... the company. Dr. Bready served as CEO ...
Breaking Biology News(10 mins):