Navigation Links
Diagenode Releases Two New Epigenetic Monoclonal 5-hmC Antibodies for Quantifying Global Hydroxymethylation
Date:9/22/2010

LIEGE, Belgium, Sept. 22 /PRNewswire/ -- Diagenode announced today that it has released two additional 5-hmC antibodies to complement its original 5-hmC (rat) monoclonal antibody. The two new 5-hmC monoclonal antibody (mouse) and polyclonal antibody (rabbit) antibodies give researchers additional choices for enriching and analyzing 5-hmC in their methylation studies.

(Photo: http://photos.prnewswire.com/prnh/20100922/NY69887 )

(Photo: http://www.newscom.com/cgi-bin/prnh/20100922/NY69887 )

The importance of 5-hmC to the epigenetic field was highlighted in a recent Epigenie review: "A year after 5-hydroxymethylcytosine's (5-hmC) dramatic entrance into the epigenetics research scene, the research community has a long list of questions to ask about the 6th base. Investigations into 5-hmC were sidelined for most of the year due to the absence of methods to analyze it. Thankfully those helpless days are history as Diagenode just launched the first 5-hmC monoclonal antibody, an innovation that makes enriching and analyzing 5-hmC a reality." (www.epigenie.com, May 11, 2010) 

These latest additions make available the broadest range of validated methylation products to the research community. Prior to this, there were no other validated antibodies available in the market for routinely identifying 5-hmC and discriminating this base from 5-mC. Diagenode and collaborators have extended validation of the 5-hmC antibody from the standard Dot Blot and Immunofluorescence approaches to hMeDIP, and hMeDIP-Seq profiling.

What is truly exciting for researchers is they will now be able to perform Dual MeDIP Assays with multiple choices of 5-hmC antibodies (Diagenode's hMeDIP kit), first by utilizing the 5-hmC monoclonal or polyclonal antibody in hMeDIP, and then the Diagenode monoclonal 33D3 MeDIP Assay (Diagenode's MeDIP kit). This approach will allow researchers to profile both types of cytosine marks in one experiment.  

Diagenode was founded in 2003. Its research and development division is continually improving its technical knowledge of DNA methylation as evident in Diagenode's Methylated DNA Immunoprecipitation (MeDIP), Bi-Sulfite, Methyl binding domain (MBD) protein (also known as MethylCap) and the gold standard 33D3 5-methylcytosine antibody (5-mC) offerings.

About Diagenode

Diagenode is a multinational life science company that develops and commercializes innovative instruments and reagents for epigenetic research. Major product lines include; IP-Star ® Automation, Bioruptor® Sonication, epigenetic targeted antibodies & kits, and methylation. Founded in 2003 in Liege (Belgium), Diagenode has offices in Liege, Belgium and Denville, New Jersey.

www.Diagenode.com


'/>"/>
SOURCE Diagenode
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Health Robotics Releases Results of First 20 i.v.STATIONs Return On Investment (ROI) Studies in the USA and Canada
2. Promega Releases 2009 Corporate Sustainability Report
3. Arrowhead Releases New Report Assessing State of Personalized Medicine Market
4. Hayes, Inc. Releases Guide to BRCA1 and BRCA2 Genetic Testing
5. MD Bioproducts Releases a New Mouse T1/ST2 ELISA
6. Centrifuge Releases New Data Visualization Software
7. Sunlight Research(TM), Releases its Osiris Therapeutics Stem Cell Patent Report
8. VKernel Releases Optimization Pack 1.2
9. Datafarm Releases New Desktop-based Application for Multi-region Viewing of eCTD Submissions: Datafarm VUE
10. SCDM Releases Best Practices for Automated Data Cleaning
11. Signatec Releases PX1500-4, Its 4-Channel, 1.5 GHz Per Channel / 2-Channel, 3 GHz Per Channel PCI-Express Digitizer with Two Virtex-5 FPGAs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... MENLO PARK, Calif., March 23, 2017  BioPharmX ... developing products for the dermatology market, today reported ... Jan. 31, 2017, and will provide an update ... from the year. "We are pleased ... productive year for BioPharmX," said President Anja Krammer. ...
(Date:3/23/2017)... -- NetworkNewsWire Editorial Coverage  ... Cancer remains one of the ... care systems, in terms of costs and resources. However, as ... development of innovative and efficient therapies that demonstrate higher chances ... of cancer treatments, a growing number of patients receiving immuno-oncology ...
(Date:3/23/2017)... YORK , March 23, 2017 ... look at four equities in the Biotech industry: Sangamo ... Synthetic Biologics Inc. (NYSE MKT: SYN), and Regulus Therapeutics ... 21 st , 2017, Credit Suisse upgraded its rating on ... by downloading their free report at: ...
(Date:3/22/2017)... ... March 22, 2017 , ... ... regeneration from small lab samples to full-size tissues, bones, even whole organs to ... vascular system that delivers blood deep into the developing tissue. , Current ...
Breaking Biology Technology:
(Date:3/16/2017)... -- CeBIT 2017 - Against identity fraud with DERMALOG solutions "Made in ... ... Used combined in one project, multi-biometric solutions provide a crucial contribution against identity fraud. (PRNewsFoto/Dermalog ... Used combined in one project, multi-biometric solutions provide ... ...
(Date:3/7/2017)... Brandwatch , the leading social intelligence company, today announces that ... uncover insights to support its reporting, help direct future campaigns, and ... youth charity will be using Brandwatch Analytics social listening and analytics ... of the topics and issues that are a priority for its ... "Until recently ...
(Date:3/2/2017)... -- Summary This report provides all the ... its partnering interests and activities since 2010. Download ... Partnering Deals and Alliance since 2010 report provides an ... the world,s leading life sciences companies. On ... inclusion of the most up to date deal and ...
Breaking Biology News(10 mins):