Navigation Links
Diagenode Introduces Innovative Bioruptor® Pico for Micro-Volume Chromatin and DNA Shearing

Denville, NJ (PRWEB) April 04, 2013

Diagenode, Inc., a leading global provider of complete solutions for epigenetics research today announced the launch of the Bioruptor® Pico, an innovative “all-in-one” sonication device for chromatin and DNA shearing. Diagenode’s Bioruptor® sonication devices use Adaptive Cavitation Technology (ACT) to create gentle, focused mechanical stress to shear biological samples in a temperature-controlled environment, highly effective for chromatin shearing, DNA & RNA shearing, cell lysis and tissue homogenization. The Bioruptor® is the most cited line of sonication devices with over 700 peer-reviewed publications.

The new Bioruptor® Pico represents a new breakthrough as an all-in-one shearing system optimized for shearing micro-volumes of 5 µl to larger volumes of up to 2 ml. This wide range enables a large variety of applications such as DNA shearing for next generation sequencing library preparation, RNA shearing, and chromatin shearing. It has been widely noted that shearing is a critical step in a number of applications. For example, the data accuracy from applications such as next generation sequencing library preparation, chromatin immunoprecipitation, and ChIP-seq depends on high-quality sample shearing and fragmentation.

"The Diagenode Bioruptor® Pico has been designed to provide the consistency, yields, and best range of fragment sizes, aspects that are critical for optimal sequencing library preparation such as in ChIP-seq and chromatin shearing” said Didier Allaer, CEO of Diagenode, “We remain committed to the epigenetics market, providing unique epigenetic solutions and innovating our line of shearing devices as the market requires increasingly smaller volumes for shearing.” In addition, the new instrument allows cost-effective shearing with sample multiplexing and simultaneous sonication of 6 to12 samples."

Manuela Saathoff, Ph.D., Product Manager for Bioruptor® stated, "The new system is smaller, lighter, and much faster than our previous models. Also the Bioruptor® Pico offers researchers flexibility for their shearing needs. Now, with just one device, you can shear chromatin and DNA in both small and large volumes.”

Regarding next generation sequencing, she also added, “for next generation sequencing library preparation, the Bioruptor® Pico achieves optimal fragmentation with the desired narrow size distribution and high quality and yields of double-stranded DNA crucial for sequencing accuracy and success.”

Diagenode has released data that can viewed at that exemplify the performance of the instrument for chromatin and DNA shearing. The company also offers a number of epigenetics products that can be used downstream in the ChIP and ChIP-seq workflow after shearing with the Bioruptor® Pico. These include highly-validated ChIP-seq antibodies, ChIP-seq kits for only 10,000 cells, and the IP-Star Compact, a unique epigenetics automation platform.

About Diagenode, Inc.:
Diagenode is a leading provider of complete solutions for epigenetic research. The company has developed a comprehensive approach to gain new insights into epigenetic studies, offering innovative shearing and automation instruments, reagent kits, and high quality antibodies to streamline DNA methylation, ChIP, and ChIP-seq workflows. The company’s latest innovations include a unique, full automation system, ChIP-seq kits for only 10,000 cells, and the industry’s most validated antibodies. For more information about Diagenode, please visit the company’s website at

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. Texas Fertility Center Introduces Oncofertility Education Program for Physicians and Patients
2. Finesse Solutions Introduces SmartParts for Intelligent Universal Controllers
3. Cearna Introduces Product Designed to Reduce Patient’s Recovery Time From Facial Plastic Surgery
4. Rigaku Introduces New Instruments at Pittcon 2013
5. GIN Introduces Advanced Robotics and Dispensing Technology at BVS La Jolla Biotech Day
6. FMC BioPolymer Introduces Its New Portfolio of Nature-Based Nutritional Solutions
7. Percival Scientific, Inc. Introduces an Affordable LED Lighting System for the Research Industry
8. Palomar Medical Center in San Diego County Introduces New Wrist-Worn Wireless Patient Vital Signs Device
9. Vista College Introduces Its New Medical Laboratory Technician Diploma Program At El Paso Campus
10. GLM Displays Introduces New Banner Stand – 10’ Tall “Giant Mosquito”
11. Rigaku introduces the world’s most comprehensive biological SAXS system for the home lab
Post Your Comments:
(Date:6/23/2016)... ... 23, 2016 , ... Charm Sciences, Inc. is pleased to ... AOAC Research Institute approval 061601. , “This is another AOAC-RI approval of the ... Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , ... secured $1 million in debt financing from Silicon Valley ... up automation and to advance its drug development efforts, ... new facility. "SVB has been an incredible ... the services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... ... 23, 2016 , ... In a new case report published today in STEM ... who developed lymphedema after being treated for breast cancer benefitted from an injection of ... dealing with this debilitating, frequent side effect of cancer treatment. , Lymphedema ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
Breaking Biology Technology:
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
(Date:4/15/2016)... 15, 2016  A new partnership announced today ... underwriting decisions in a fraction of the time ... and high-value life insurance policies to consumers without ... With Force Diagnostics, rapid testing (A1C, Cotinine and ... (blood pressure, weight, pulse, BMI, and activity data) ...
Breaking Biology News(10 mins):