Oakland, CA (PRWEB) May 25, 2013
Dennis R. HIll M.D. Radiation Oncologist at the Alta Bates Summit Medical Center in Oakland, CA reports that recently there has been a promotion of the idea that a newer isotope Cesium 131 has markedly improved the permanent seed, or low dose rate, brachytherapy for prostate cancer. The claim is that this newer isotope has a higher energy, a shorter half life, and gives a higher biologically effective dose to the tumor. It is true that Cesium 131 has a higher average energy than the other commonly used prostate cancer permanent seed isotopes on the market. The more commonly used isotopes used are Palladium 103 and Iodine 125. Cesium 131 delivers 90% of the prescribed dose to the prostate gland in 33 days compared to 58 days for Palladium 103 and 204 days for Iodine 125. Another claimed benefit to the short half-life of Cesium 131 is what is known as the “biological effective dose” against cancers exhibiting different characteristics – for instance, slow versus fast growing tumors. This all sounds good and it is an improvement over conventional low dose rate permanent seed brachytherapy with Palladium 103 or Iodine 125.
Dr. Hill answers the question, how does Cesium 131 compares to temporary high dose rate brachytherapy, one of the newest prostate cancer treatment options? High dose rate brachytherapy delivers the entire dose in two treatments over eight days compared to 33 days with Cesium 131. Prostate cancer, unlike some other cancers can have a slower growth rate which can be closer to normal tissue than the more virulent cancers. Research has shown that larger doses of radiation over a shorter period of time as delivered by high dose rate brachytherapy may be radiobiologically superior to the protracted low doses over a long time that permanent seeds delivers, including Cesium 131.
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